LEADER 05207nam 2200601Ia 450 001 9910784598403321 005 20230828175514.0 010 $a1-280-64180-0 010 $a9786610641802 010 $a0-08-046212-X 035 $a(CKB)1000000000357846 035 $a(EBL)270363 035 $a(OCoLC)271306479 035 $a(SSID)ssj0000254828 035 $a(PQKBManifestationID)12048214 035 $a(PQKBTitleCode)TC0000254828 035 $a(PQKBWorkID)10208835 035 $a(PQKB)11120592 035 $a(MiAaPQ)EBC270363 035 $a(PPN)132410583 035 $a(EXLCZ)991000000000357846 100 $a20050826d2006 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aSynthesis of essential drugs /$fR?. S. Vardanyan, V. J. Hruby 210 1$aAmsterdam ;$aLondon :$cElsevier,$d2006. 215 $a1 online resource (xvi, 617 pages) $cillustrations 311 0 $a0-444-52166-6 320 $aIncludes bibliographical references and index. 327 $afront cover; copyright; front matter; Preface; table of contents; body; General Anesthetics; Inhalation Anesthetics; Noninhalation Anesthetics; Local Anesthetics; Local Anesthetics of the Aminoether Series; Local Anesthetics of the Aminoamide Series; Topical Anesthetics; Analgesics; Opioid Analgesics; Agonists; Mixed agonists/antagonists; Opioid antagonists; Nonsteroid Anti-Inflammatory Drugs and Anti-Fever Analgesics; Salicylic acid derivatives; Pyrazolonees; p-Aminophenol derivatives; Anthranylic acid derivatives; Propionic acid derivatives; Acetic acid derivatives 327 $aIndolyl/indeneacetic acids; Oxicames; Soporific Agents (Hypnotics and Sedative Drugs); Barbiturates; Long-acting barbiturates; Intermediate-acting barbiturates; Short-action barbiturates; Ultrashort-action barbiturates; Benzodiazepines; Other Hypnotics and Sedative Drugs; Anxiolytics (Tranquilizers); Benzodiazepines; Anxiolytic of Nonbenzodiazepine Structures; Antipsychotics (Neuroleptics); Phenothiazine Derivatives; Thioxanthene Derivatives; Butyrophenone Derivatives; Dihydroindolone Derivatives; Dibenzoxazepine and Dibenzdiazepine Derivatives; Diphenylbutylpiperidine Derivatives 327 $aOther Neuroleptics; Lithium Derivatives; Antidepressants; Tricyclic Antidepressants; Tertiary amines-representatives of tricyclic antidepressants; Secondary amines-representatives of tricyclic antidepressants; Monoaminooxidase Inhibitors; Second-Generation Antidepressants (Atypical Antidepressants); Amphetamines and Other CNS Stimulators; Central Nervous System Stimulants; Psychomotor Stimulants; Methylxanthines; Amphetamines, methylphenidate, and pemoline; Respiratory Stimulants or Analeptics; Appetite Suppressants or Anorectics; Antiepileptic Drugs; Hydantoin Derivatives; Barbiturates 327 $aSuccinimides; Valproic Acid; Carbamazepine; Benzodiazepines; Acetazolamide; Oxazolidines; Antiparkinsonian Drugs; Drugs Affecting the Dopaminergic Systems of the Brain; Anticholinergic Drugs (Central Cholinoblockers); Adrenergic (Sympathomimetic) Drugs; Direct-Acting Agonists; Drugs stimulating ?- and ?-adrenoreceptors; Drugs stimulating predominantly ?-adrenoreceptors; Drugs stimulating predominantly ?-adrenoreceptors; Antiedema sympathomimetics; Indirect-Acting Agonists; Agonists of Mixed Action; Adrenoblocking Drugs; ?-Adrenoblockers; ?-Adrenoblockers; Long-lasting noncompetitive antagonists 327 $aNonselective, reversible competitive adrenoblockers; Reversible, competitive ?1-selective adrenoblockers; Ergot alkaloids (alkaloids of ergot); Selective ?2-adrenoblockers; Adrenergic Neuron Blockers; Cholinomimetics; Direct-Acting Cholinomimetics; Choline esters; Natural muscarinic alkaloids; Natural nicotinic alkaloids; Indirect-Acting Cholinomimetics; Reversible cholinesterase inhibitors; Carbamates; Quaternary amines; Irreversible cholinesterase inhibitors; Other organophosphorous cholinesterase inhibitors; Anticholinergic Drugs; Antimuscarinic Drugs; Alkaloids; Anticholinergics of the quaternary amine series 330 $aThis book represents an effort to express a long overdue need of compiling information which has been accumulated over the course of more than 30 years of our work in the area of the synthesis of medicinal drugs. Our effort fills obvious gaps that exist in the literature of drug synthesis. The synthesis of various groups of drugs are presented in an order similar to that traditionally presented in a pharmacology curriculum. This was done with a very specific goal in mind - to harmonize the chemical aspects with the pharmacology curriculum in a manner useful to chemists. 606 $aPharmaceutical chemistry 606 $aDrugs$xDesign 615 0$aPharmaceutical chemistry. 615 0$aDrugs$xDesign. 676 $a615.19 676 $a615.7 700 $aVardanyan$b R?uben$0722711 701 $aHruby$b Victor J.$f1938-$094130 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910784598403321 996 $aSynthesis of essential drugs$91409491 997 $aUNINA