LEADER 05715nam 2200745Ia 450 001 9910784549503321 005 20230120004821.0 010 $a1-281-03695-1 010 $a9786611036959 010 $a0-08-054310-3 035 $a(CKB)1000000000364685 035 $a(EBL)299439 035 $a(OCoLC)476077139 035 $a(SSID)ssj0000914321 035 $a(PQKBManifestationID)11561940 035 $a(PQKBTitleCode)TC0000914321 035 $a(PQKBWorkID)10878851 035 $a(PQKB)10980884 035 $a(SSID)ssj0000167934 035 $a(PQKBManifestationID)12036692 035 $a(PQKBTitleCode)TC0000167934 035 $a(PQKBWorkID)10178807 035 $a(PQKB)11589178 035 $a(MiAaPQ)EBC299439 035 $a(EXLCZ)991000000000364685 100 $a20060124d2006 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aToxicology of organophosphate and carbamate compounds$b[electronic resource] /$fedited by Ramesh C. Gupta 210 $aAmsterdam ;$aBoston $cElsevier Academic Press$dc2006 215 $a1 online resource (781 p.) 300 $aDescription based upon print version of record. 311 $a0-12-088523-9 320 $aIncludes bibliographical references and index. 327 $aFront Cover; Toxicology of Organophosphate and Carbamate Compounds; Copyright Page; Contents; Contributors; Foreword; Section I: Uses, Abuses, & Epidemiology; Chapter 1. Introduction; Chapter 2. Classification and Uses of Organophosphates and Carbamates; Chapter 3. Therapeutic Uses of Cholinesterase Inhibitors in Neurodegenerative Diseases; Chapter 4. Coadministration of Memantine with Acetylcholinesterase Inhibitors: Preclinical and Clinical Evidence; Chapter 5. Cholinesterase Inhibitors as Chemical Warfare Agents: Community Preparedness Guidelines 327 $aChapter 6. Organophosphates and the Gulf War SyndromeChapter 7. The Bhopal Accident and Methyl Isocyanate Toxicity; Chapter 8. Global Epidemiology of Organophosphate and Carbamate Poisonings; Section II: Pharmacokinetics & Metabolism; Chapter 9. Physiologically Based Pharmacokinetic Modeling of Organophosphorus and Carbamate Pesticides; Chapter 10. Metabolism of Organophosphorus and Carbamate Pesticides; Chapter 11. Interspecies Variation in Toxicity of Cholinesterase Inhibitors; Section III: Esterases, Receptors, Mechanisms, & Tolerance Development 327 $aChapter 12. Structure and Function of CholinesterasesChapter 13. Cholinesterase Pharmacogenetics; Chapter 14. Methods for Measuring Cholinesterase Activities in Human Blood; Chapter 15. Interactions of Organophosphorus and Carbamate Compounds with Cholinesterases; Chapter 16. Structure, Function, and Regulation of Carboxylesterases; Chapter 17. Noncholinesterase Mechanisms of Central and Peripheral Neurotoxicity: Muscarinic Receptors and Other Targets; Chapter 18. Paraoxonase Polymorphisms and Toxicity of Organophosphates 327 $aChapter 19. Tolerance Development to Toxicity of Cholinesterase InhibitorsSection IV: Organ Toxicity; Chapter 20. Central Nervous System Effects and Neurotoxicity; Chapter 21. Developmental Neurotoxicity of Organophosphates: A Case Study of Chlorpyrifos; Chapter 22. In Vitro Models for Testing Organophosphate-lnduced Neurotoxicity and Remediation; Chapter 23. Electrophysiological Mechanisms in Neurotoxicity of Organophosphates and Carbamates; Chapter 24. Behavioral Toxicity of Cholinesterase Inhibitors; Chapter 25. Peripheral Nervous System Effects and Delayed Neuropathy 327 $aChapter 26. Intermediate Syndrome in Organophosphate PoisoningChapter 27. Cardiovascular Toxicity of Cholinesterase lnhibitors; Chapter 28. Pulmonary Toxicity of Cholinesterase Inhibitors; Chapter 29. Approaches to Defining and Evaluating the Inhalation Pharmacology and Toxicology Hazards of Anticholinesterases; Chapter 30. Dermal Absorption/Toxicity of Organophosphates and Carbamates; Chapter 31. Local and Systemic Ophthalmic Pharmacology and Toxicology of Organophosphate and Carbamate Anticholinesterases; Chapter 32. Reproductive Toxicity of Organophosphate and Carbamate Pesticides 327 $aChapter 33. Placental Toxicity of Organophosphate and Carbamate Pesticides 330 $aThis text/reference book provides the most comprehensive coverage of anticholinesterase compounds (Organophosphates and Carbamates), which constitute the largest number of chemicals that are primarily used as insecticides in agriculture, industry, and around the home/garden. Some OPs (nerve agents) have been used in chemical warfare and terrorist attacks, while some OPs and CMs have been recommended as therapeutic agents in human medicine as well as in veterinary medicine. Many chemicals of both classes are extremely toxic and lack selectivity, thus their inadvertent/accidental use continues t 606 $aOrganophosphorus compounds$xToxicology 606 $aCarbamates$xToxicology 606 $aCholinesterase inhibitors$xToxicology 606 $aPesticides$xToxicology 606 $aInsecticides$xToxicology 615 0$aOrganophosphorus compounds$xToxicology. 615 0$aCarbamates$xToxicology. 615 0$aCholinesterase inhibitors$xToxicology. 615 0$aPesticides$xToxicology. 615 0$aInsecticides$xToxicology. 676 $a615.9/02 22 676 $a615.902 676 $a616.80461 701 $aGupta$b Ramesh C$g(Ramesh Chandra),$f1949-$0866223 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910784549503321 996 $aToxicology of organophosphate and carbamate compounds$93765925 997 $aUNINA