LEADER 04995nam 22007932 450 001 9910783285903321 005 20151005020622.0 010 $a1-107-13084-0 010 $a1-280-16081-0 010 $a9786610160815 010 $a0-511-11960-7 010 $a1-139-14725-0 010 $a0-511-06360-1 010 $a0-511-05727-X 010 $a0-511-33094-4 010 $a0-511-54586-X 010 $a0-511-07206-6 035 $a(CKB)1000000000018459 035 $a(EBL)217765 035 $a(OCoLC)70730136 035 $a(SSID)ssj0000153202 035 $a(PQKBManifestationID)11158738 035 $a(PQKBTitleCode)TC0000153202 035 $a(PQKBWorkID)10392536 035 $a(PQKB)11059675 035 $a(UkCbUP)CR9780511545863 035 $a(Au-PeEL)EBL217765 035 $a(CaPaEBR)ebr10069971 035 $a(CaONFJC)MIL16081 035 $a(MiAaPQ)EBC217765 035 $a(PPN)26135373X 035 $a(EXLCZ)991000000000018459 100 $a20090507d2002|||| uy| 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aFamilial breast and ovarian cancer $egenetics, screening, and management /$fedited by Patrick J. Morrison, Shirley V. Hodgson, and Neva E. Haites$b[electronic resource] 210 1$aCambridge :$cCambridge University Press,$d2002. 215 $a1 online resource (xv, 401 pages) $cdigital, PDF file(s) 300 $aTitle from publisher's bibliographic system (viewed on 05 Oct 2015). 311 $a0-521-01777-7 311 $a0-521-80373-X 320 $aIncludes bibliographical references and index. 327 $aCh. 1. Introduction -- Ch. 2. Overview of the clinical genetics of breast cancer -- Ch. 3. Cowden syndrome and related disorders -- Ch. 4. Overview of the clinical genetics of ovarian cancer -- Ch. 5. Ovarian and breast cancer as part of hereditary non-polyposis colorectal cancer (HNPCC) and other hereditary colorectal cancer syndromes -- Ch. 6. The natural history of hereditary breast cancer -- Ch. 7. Pathology of the breast and ovary in mutation carriers -- Ch. 8. Risk estimation for familial breast and ovarian cancer -- Ch. 9. Developing a cancer genetics service: a Welsh model -- Ch. 10. Referral criteria for cancer genetics clinics -- Ch. 11. Guidelines for the development of cancer genetics services -- Ch. 12. Cultural and educational aspects influencing the development of cancer genetics services in different European countries -- Ch. 13. Screening, detection and survival patterns of breast and other cancers in high-risk families -- Ch. 14. Screening for familial ovarian cancer -- Ch. 15. Management of BRCA1/2 mutation carriers -- Ch. 16. Management of familial ovarian cancer -- Ch. 17. Prophylactic mastectomy in mutation carriers -- Ch. 18. Psychosocial aspects of genetic counselling for breast and ovarian cancer -- Ch. 19. BRCA1/2 testing: uptake and its measurement -- Ch. 20. Breast cancer genetics: ethical, social and insurance issues -- Ch. 21. Gene therapy for breast and ovarian cancer -- Ch. 22. Future directions. 330 $aThis publication surveys the profound and far-reaching ramifications that have arisen from the very significant advances in our understanding of the genetic basis of familial breast and ovarian cancer. Written by international experts from Europe and North America, this book provides the busy clinician with a contemporary and wide-ranging guide to the latest developments in the diagnosis, genetics, screening, prevention and management of familial breast cancer. This area has advanced in knowledge so rapidly that this publication provides an unrivalled source of information including sections on ethical and insurance issues and the different cultural differences in breast cancer. The use of recently devised cancer genetics clinics and different referral criteria and patterns to these clinics are detailed. The volume will be of immense value to all clinical geneticists, oncologists, and healthcare professionals involved in screening and counselling programmes. 517 3 $aFamilial Breast & Ovarian Cancer 606 $aBreast$xCancer 606 $aBreast$xCancer$xGenetic aspects 606 $aOvaries$xCancer 606 $aOvaries$xCancer$xGenetic aspects 615 0$aBreast$xCancer. 615 0$aBreast$xCancer$xGenetic aspects. 615 0$aOvaries$xCancer. 615 0$aOvaries$xCancer$xGenetic aspects. 676 $a616.99/449 702 $aMorrison$b Patrick J$g(Patrick John),$f1963- 702 $aHodgson$b S. V. 702 $aHaites$b Neva E$g(Neva Elizabeth),$f1947- 702 $aMorrison$b Patrick J$g(Patrick John),$f1963- 702 $aHodgson$b S. V. 702 $aHaites$b Neva E$g(Neva Elizabeth),$f1947- 801 0$bUkCbUP 801 1$bUkCbUP 906 $aBOOK 912 $a9910783285903321 996 $aFamilial breast and ovarian cancer$93738559 997 $aUNINA