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100   $a20090508d2002||||  uy|            0
101 0 $aeng
135   $aur|||||||||||
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aPathway analysis and optimization in metabolic engineering /$fNe?stor V. Torres, Eberhard O. Voit$b[electronic resource]
210  1$aCambridge :$cCambridge University Press,$d2002.
215   $a1 online resource (xiv, 305 pages) $cdigital, PDF file(s)
300   $aTitle from publisher's bibliographic system (viewed on 05 Oct 2015).
311   $a0-511-06322-9 
311   $a0-521-80038-2 
320   $aIncludes bibliographical references and index.
327   $aCover; Half-title; Title; Copyright; Dedication; Contents; Preface; CHAPTER ONE Target: A Useful Model; CHAPTER TWO Methods of Biochemical Systems Theory; CHAPTER THREE A Model of Citric Acid Production in the Mold Aspergillus niger; CHAPTER FOUR Optimization Methods; CHAPTER FIVE Optimization of Biochemical Systems; CHAPTER SIX Optimization of Citric Acid Production in Aspergillus niger; CHAPTER SEVEN Maximization of Ethanol Production in Saccharomyces cerevisiae; CHAPTER EIGHT Conclusions; Author Index; Subject Index
330   $aFacility in the targeted manipulation of the genetic and metabolic composition of organisms, combined with unprecedented computational power, is forging a niche for a new subspecialty of biotechnology called metabolic engineering. First published in 2002, this book introduces researchers and advanced students in biology and engineering to methods of optimizing biochemical systems of biotechnological relevance. It examines the development of strategies for manipulating metabolic pathways, demonstrates the need for effective systems models, and discusses their design and analysis, while placing special emphasis on optimization. The authors propose power-law models and methods of biochemical systems theory toward these ends. All concepts are derived from first principles, and the text is richly illustrated with numerous graphs and examples throughout. Special features include: nontechnical and technical introductions to models of biochemical systems; a review of basic methods of model design and analysis; concepts of optimization; and detailed case studies.
517 3 $aPathway Analysis & Optimization in Metabolic Engineering
606   $aBiochemical engineering$xMathematical models
606   $aMathematical optimization
606   $aSystem theory
615  0$aBiochemical engineering$xMathematical models.
615  0$aMathematical optimization.
615  0$aSystem theory.
676   $a660.6/3
700   $aTorres$b Ne?stor V.$f1958-$01566487
702   $aVoit$b Eberhard O.
801  0$bUkCbUP
801  1$bUkCbUP
906   $aBOOK
912   $a9910783229603321
996   $aPathway analysis and optimization in metabolic engineering$93837022
997   $aUNINA