LEADER 03690nam 2200637Ia 450 001 9910782655103321 005 20230721004539.0 010 $a0-309-17865-7 010 $a1-281-80023-6 010 $a9786611800239 010 $a0-309-10743-1 035 $a(CKB)1000000000705282 035 $a(EBL)3378407 035 $a(SSID)ssj0000097237 035 $a(PQKBManifestationID)11122248 035 $a(PQKBTitleCode)TC0000097237 035 $a(PQKBWorkID)10113248 035 $a(PQKB)11492283 035 $a(MiAaPQ)EBC3378407 035 $a(Au-PeEL)EBL3378407 035 $a(CaPaEBR)ebr10255035 035 $a(CaONFJC)MIL180023 035 $a(OCoLC)923279359 035 $a(EXLCZ)991000000000705282 100 $a20080917d2008 ua 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aAddressing the barriers to pediatric drug development$b[electronic resource] $eworkshop summary /$fCori Vanchieri, Adrienne Stith Butler, and Andrea Knutsen, rapporteurs ; Forum on Drug Discovery, Development, and Translation, Board on Health Sciences Policy, Institute of Medicine of the National Academies 210 $aWashington, D.C. $cNational Academies Press$dc2008 215 $a1 online resource (65 p.) 300 $aDescription based upon print version of record. 311 $a0-309-10742-3 320 $aIncludes bibliographical references (p. 41-42). 327 $a""Reviewers""; ""Contents""; ""Summary""; ""1 Introduction""; ""2 Regulatory Framework""; ""3 Current Challenges in Developing and Prescribing Drugs for Children""; ""4 Models for Enhancing Pediatric Drug Development""; ""5 Challenges and Opportunities for the Future""; ""References""; ""Appendixes""; ""Appendix A: Workshop Agenda""; ""Appendix B: Speaker Biographies"" 330 $aDecades of research have demonstrated that children do not respond to medications in the same way as adults. Differences between children and adults in the overall response to medications are due to profound anatomical, physiological, and developmental differences. Although few would argue that children should receive medications that have not been adequately tested for safety and efficacy, the majority of drugs prescribed for children--50 to 75 percent-- have not been tested in pediatric populations. Without adequate data from such testing, prescribing drugs appropriately becomes challenging for clinicians treating children, from infancy through adolescence. Addressing the Barriers to Pediatric Drug Development is the summary of a workshop, held in Washington, D.C. on June 13, 2006, that was organized to identify barriers to the development and testing of drugs for pediatric populations, as well as ways in which the system can be improved to facilitate better treatments for children. 606 $aDrugs$xTesting$xLaw and legislation$zUnited States 606 $aPediatric pharmacology$xLaw and legislation$zUnited States 606 $aPediatric pharmacology$xResearch$zUnited States 615 0$aDrugs$xTesting$xLaw and legislation 615 0$aPediatric pharmacology$xLaw and legislation 615 0$aPediatric pharmacology$xResearch 676 $a615.58083 701 $aButler$b Adrienne Stith$01470578 701 $aKnutsen$b Andrea$01578442 701 $aVanchieri$b Cori$01546613 712 02$aInstitute of Medicine (U.S.).$bForum on Drug Discovery, Development, and Translation. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910782655103321 996 $aAddressing the barriers to pediatric drug development$93857766 997 $aUNINA LEADER 01878nam0 2200349 i 450 001 CFI0009035 005 20251003044107.0 010 $a882450194X 020 $aIT$b87-3878 100 $a20071004d1984 ||||0itac50 ba 101 | $aita 102 $ait 181 1$6z01$ai $bxxxe 182 1$6z01$an 200 1 $aInflazione, aspettative e prezzi relativi$fAlex Cukierman 210 $aMilano$cEdizioni di Comunità$d1984 215 $a203 p.$d23 cm 225 | $aSaggi brevi di economia$fa cura della Banca commerciale italiana$v7 300 $aTrad. dall'inglese di Alberto Alesina, Gian Luigi Costanzo. 410 0$1001CFI0005778$12001 $aSaggi brevi di economia$fa cura della Banca commerciale italiana$v7$171202$aBanca commerciale italiana$3CFIV001866 606 $aInflazione$2FIR$3CFIC001034$9E 676 $a332.4$9Moneta$v12 676 $a332.41$9MONETA. VALORE$v23 700 1$aCukierman$b, Alex$3CFIV015336$4070$0119785 801 3$aIT$bIT-000000$c20071004 850 $aIT-BN0095 901 $bNAP 01$cPOZZO LIB.$nVi sono collocati fondi di economia, periodici di ingegneria e scienze, periodici di economia e statistica e altri fondi comprendenti documenti di economia pervenuti in dono. 912 $aCFI0009035 950 0$aBiblioteca Centralizzata di Ateneo$c1 v.$d 01POZZO LIB.DONI DEMM 76$e 01 0000093195E VMA 1 v.$fB $h20221205$i20221205$c1 v.$d 01POZZO LIB.F. ASSANTE 330$e 0101 0060016715E VMA 1 v. (Precedente collocazione A 540)$fB $h20220923$i20220923$c1 v.$d 01POZZO LIB.F. PARRAVICINI 414$e 0101 0600162755E VMA 1 v. (Precedente collocazione P 419)$fB $h20221102$i20221102 977 $a 01 996 $aInflation, stagflation, the Phillips curve and relative prices$934334 997 $aUNISANNIO