LEADER 05064nam 2200673Ia 450 001 9910782391703321 005 20230607222124.0 010 $a1-281-96066-7 010 $a9786611960667 010 $a981-281-164-8 035 $a(CKB)1000000000538060 035 $a(EBL)1681686 035 $a(OCoLC)815756561 035 $a(SSID)ssj0000229740 035 $a(PQKBManifestationID)11176060 035 $a(PQKBTitleCode)TC0000229740 035 $a(PQKBWorkID)10173156 035 $a(PQKB)10145897 035 $a(MiAaPQ)EBC1681686 035 $a(WSP)00004617 035 $a(Au-PeEL)EBL1681686 035 $a(CaPaEBR)ebr10255870 035 $a(CaONFJC)MIL196066 035 $a(EXLCZ)991000000000538060 100 $a20011221d2001 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aProton radiotherapy accelerators$b[electronic resource] /$fWioletta Wieszczycka, Waldemar H. Scharf 210 $aRiver Edge, NJ $cWorld Scientific$dc2001 215 $a1 online resource (342 p.) 300 $aDescription based upon print version of record. 311 $a981-02-4528-9 320 $aIncludes bibliographical references (p. 307-317) and index. 327 $aCONTENTS ; PREFACE ; CHAPTER 1 INTRODUCTION ; 1.1 Cancer and Radiation Therapy ; 1.2 Historical Development of Radiation Therapy ; 1.3 Modern Tools for Conventional Radiotherapy ; 1.3.1 Main Parameters of Conventional Therapy Beams ; 1.3.2 Elements of Conventional Accelerator System 327 $a1.3.3 Reasons for Development of Non-conventional Radiotherapies1.4 Glossary ; 1.4.1 Beam Intensity ; 1.4.2 Beam Range in an Absorbing Medium ; 1.4.3 Bragg Peak Modulation ; 1.4.4 Range Adjustment ; 1.4.5 Radiation Field ; 1.4.6 Field Homogeneity on a Transverse Section 327 $a1.4.7 Homogeneity Region in a Plane Orthogonal to the Beam Direction 1.4.8 Field Homogeneity along the Beam Axis ; 1.4.9 Field Symmetry ; 1.4.10 Lateral Penumbra ; 1.4.11 Distal Dose Fall-off ; CHAPTER 2 PHYSICAL AND RADIOBIOLOGICAL PROPERTIES OF HADRONS 327 $a2.1 Basic Facts in Radiotherapy 2.1.1 Dose-Effects Curves ; 2.1.2 RBE Dependence on LET and OER ; 2.2 An Introduction to Hadrontherapy ; 2.3 Energy Loss ; 2.3.1 Nuclear Energy Loss ; 2.3.2 Electronic Energy Loss ; 2.3.3 Range and Bragg Curves 327 $a2.3.4 Track Formation and Radial Dose Distribution 2.4 Interaction of Hadrons with Biological Matter ; 2.4.1 Cellular Organization and the Target of Radiation Action ; 2.4.2 Hadrons' Track in Biological Matter ; 2.4.3 RBE of Hadrons ; 2.4.4 Fractionation and Oxygen Effect 327 $aCHAPTER 3 STATUS OF CLINICAL RESEARCH IN PROTONTHERAPY 330 $a Hadronic radiotherapy uses particle beams to treat tumors located near critical body structures and tumors that respond poorly to conventional photon and electron beam radiotherapy. Initial research in hadronic radiotherapy was performed using accelerators built for physics research. The good results of the proton and ion therapy programs have enhanced the tendency to use protontherapy as a routine method. There are about 20 working protontherapy facilities (first, second and third generation) and more than 30 centers are planned. This book presents the first comprehensive overview of the fi 606 $aProton accelerators 606 $aRadiotherapy, High energy$xEquipment and supplies 606 $aParticles (Nuclear physics) 615 0$aProton accelerators. 615 0$aRadiotherapy, High energy$xEquipment and supplies. 615 0$aParticles (Nuclear physics) 676 $a615.842 700 $aWieszczycka$b Wioletta$0770624 701 $aScharf$b Waldemar$051451 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910782391703321 996 $aProton radiotherapy accelerators$91572526 997 $aUNINA