LEADER 05158nam 2200661Ia 450 001 9910782116903321 005 20230617040912.0 010 $a1-281-93570-0 010 $a9786611935702 010 $a981-279-529-4 035 $a(CKB)1000000000537838 035 $a(EBL)1679330 035 $a(OCoLC)879023478 035 $a(SSID)ssj0000113723 035 $a(PQKBManifestationID)11140588 035 $a(PQKBTitleCode)TC0000113723 035 $a(PQKBWorkID)10100352 035 $a(PQKB)11258515 035 $a(MiAaPQ)EBC1679330 035 $a(WSP)00005233 035 $a(Au-PeEL)EBL1679330 035 $a(CaPaEBR)ebr10255790 035 $a(CaONFJC)MIL193570 035 $a(EXLCZ)991000000000537838 100 $a20040427d2003 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aBone morphogenetic protein and collagen$b[electronic resource] $ean advances in tissue banking specialist publication /$feditor, Glyn O. Phillips 210 $aRiver Edge, NJ $cWorld Scientific$dc2003 215 $a1 online resource (169 p.) 225 1 $aSeries in allografts in bone healing ;$vv. 2 300 $a"An Advances in tissue banking specialist publication." 311 $a981-238-318-2 320 $aIncludes bibliographical references. 327 $aCONTENTS ; Introduction to the Series ; Preface ; List of Contributors ; Chapter 1 From Bone Allografts to Synthetic Bone Grafts: Bone Morphogenetic Proteins and Osteoinduction ; 1. Introduction ; 2. Bone Morphogenesis is a Cascade 327 $a3. Purification Cloning and Expression of Recombinant BMPs 4. BMPs and Chondrogenesis and Cartilage Maintenance ; 5. BMPs: Pleiotropy and Thresholds ; 6. BMP Receptors and Smads ; 7. BMPs: Clinical Applications ; 8. Acknowledgements ; 9. References 327 $aChapter 2 The Osteoinductive Properties of Demineralised Bone Matrix Grafts 1. Introduction ; 2. Factors Affecting the Osteoinductivity of DBM Grafts ; 3. Cellular Effects of DBM Grafts ; 4. The BMPs ; 5. DBM Grafts in Clinical Use ; 6. Assays For DBM Activity ; 7. References 327 $aChapter 3 Processing Factors Contributing To Production Of Maximally Osteoinductive Demineralised Ground Bone For Use In Orthopaedic Or Periodontal Applications 1. Introduction ; 2. Cleaning of Bone ; 3. Demineralization of Bone ; 4. Determination of Osteoinductive Potential of Bone 327 $a5. Summary and Conclusions 6. References ; Chapter 4 Clinical Effectiveness of Demineralised Bone Matrix Assayed in Human Cell Culture ; 1. Introduction ; 2. Material and Methods ; 3. Results ; 4. Discussion ; 5. Acknowledgement ; 6. References 327 $aChapter 5 The Influence of Sterilisation on the Osteoinductive Properties of Bone in Rat Bone Marrow Cell Culture 330 $aWhat are bone morphogenetic proteins (BMPs) and how can they be used in orthopaedic practice? Ever since Urist proposed in 1976 that protein factors from cortical bone appeared to modulate bone healing in animals, there has been a search for these mysterious osteoinductive components. Now that their structure has been elucidated, they have been purified and cloned, and are now available for the improvement of bone healing. The best source of BMPs is demineralised bone. This bone allograft is used to achieve greater osteoinductive capacity. But are the actions of procurement, processing, demi 410 0$aAllografts in bone healing ;$vv. 2. 606 $aBone morphogenetic proteins 606 $aCollagen 615 0$aBone morphogenetic proteins. 615 0$aCollagen. 676 $a612.75 701 $aPhillips$b Glyn O$022968 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910782116903321 996 $aBone morphogenetic protein and collagen$93692682 997 $aUNINA