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101 0 $aeng
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181   $ctxt$2rdacontent
182   $cc$2rdamedia
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200 10$aFacilitative Glucose Transporters in Articular Chondrocytes$b[electronic resource] $eExpression, Distribution and Functional Regulation of GLUT Isoforms by Hypoxia, Hypoxia Mimetics, Growth Factors and Pro-Inflammatory Cytokines /$fby Ali Mobasheri, Carolyn A. Bondy, Kelle Moley, Alexandrina Ferreira Mendes, Susana Carvalho Rosa, Stephen Richardson, Judith A Hoyland, Richard Barrett-Jolley, Mehdi Shakibaei
205   $a1st ed. 2008.
210  1$aBerlin, Heidelberg :$cSpringer Berlin Heidelberg :$cImprint: Springer,$d2008.
215   $a1 online resource  (vi, 88 pages) $cillustrations
225 1 $aAdvances in Anatomy, Embryology and Cell Biology,$x2192-7065 ;$v200
300   $aDescription based upon print version of record.
311 0 $a3-540-78898-0 
320   $aIncludes bibliographical references and index.
327   $aArticular Cartilage: Structure, Function, and Pathophysiology -- Does Arthritis Have a Nutritional Etiology? -- Metabolic Dysfunction in Arthritis -- Glucose: An Essential Metabolite and Structural Precursor for Articular Cartilage -- Mammalian Sugar Transporter Families: GLUT and SGLT -- Molecular Diversity of Facilitative Glucose Transporters in Articular Chondrocytes -- Regulation of Glucose Transport by Nonsteroidal Anti-inflammatory Drugs -- Glucose Transporters in the Intervertebral Disc -- Glucose Transporter Expression and Regulation in Embryonic and Mesenchymal Stem Cells -- Concluding Remarks.
330   $aArticular cartilage is a unique and highly specialized avascular connective tissue in which the availability of oxygen and glucose is significantly lower than synovial fluid and plasma. Glucose is an essential source of energy during embryonic growth and fetal development and is vital for mesenchymal cell differentiation, chondrogenesis and skeletal morphogenesis. Glucose is an important metabolic fuel for differentiated chondrocytes during post-natal development and in adult articular cartilage and is a common structural precursor for the synthesis of extracellular matrix glycosaminoglycans.
410  0$aAdvances in Anatomy, Embryology and Cell Biology,$x2192-7065 ;$v200
606   $aMedicine$xResearch
606   $aBiology$xResearch
606   $aOrthopedics
606   $aEndocrinology
606   $aBiomedical Research
606   $aOrthopaedics
606   $aEndocrinology
615  0$aMedicine$xResearch.
615  0$aBiology$xResearch.
615  0$aOrthopedics.
615  0$aEndocrinology.
615 14$aBiomedical Research.
615 24$aOrthopaedics.
615 24$aEndocrinology.
676   $a612.75
676   $a613.283
701   $aMobasheri$b A$g(Ali)$01469261
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906   $aBOOK
912   $a9910782093903321
996   $aFacilitative Glucose Transporters in Articular Chondrocytes$93680687
997   $aUNINA