LEADER 05014nam 22006134a 450 001 9910144557503321 005 20170810191435.0 010 $a1-280-51954-1 010 $a9786610519545 010 $a3-527-60466-9 010 $a3-527-60407-3 035 $a(CKB)1000000000377165 035 $a(EBL)482362 035 $a(OCoLC)68571538 035 $a(SSID)ssj0000119183 035 $a(PQKBManifestationID)11129652 035 $a(PQKBTitleCode)TC0000119183 035 $a(PQKBWorkID)10058034 035 $a(PQKB)10264845 035 $a(MiAaPQ)EBC482362 035 $a(EXLCZ)991000000000377165 100 $a20060808d2005 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aCell migration in development and disease$b[electronic resource] /$fedited by Doris Wedlich 210 $aWeinheim $cWiley-VCH$dc2005 215 $a1 online resource (399 p.) 300 $aDescription based upon print version of record. 311 $a3-527-30587-4 320 $aIncludes bibliographical references and index. 327 $aCell Migrationin Development and Disease; Contents; Preface; List of Contributors; Color Plates; I Cell Shape Modulations and Cell Surface-Nucleus Connections: Prerequisites for Cell Migration; 1 Functional Phases in Cell Attachment and Spreading; 1.1 Introduction; 1.2 Fibroblast Spreading on Matrices; 1.3 Summary of Spreading Process; 1.3.1 Steps in Cell Spreading; 1.3.1.1 Basal Motility Phase (Cells in Suspension); 1.3.1.2 Adhesion to the Surface; 1.3.1.3 Initiation of Actin Assembly and Spreading (Rate-limiting Step); 1.3.1.4 Continued Spreading; 1.3.1.5 Transition to Fully Spread State 327 $a1.3.2 Binding to Rigid Matrices Causes Strengthening of Cytoskeleton-Integrin Linkages1.3.2.1 Initial Binding of Fibronectin Multimers at the Leading Edge and Over Actin Cables; 1.3.2.2 Force-dependent Activation of the ECM-Integrin Complexes; 1.3.2.3 Additional Steps in the Spreading Process; 1.3.3 MTs and Motility; 1.3.4 Conclusion; 1.4 References; 2 Polarized Cell Motility: Microtubules Show the Way; 2.1 Introduction; 2.1.1 The Vasiliev Conundrum; 2.1.2 Cell Polarity and Adhesion; 2.2 Microtubules Meet the Actin Cytoskeleton at Focal Adhesions 327 $a2.3 Microtubule Targeting Promotes Focal Adhesion Turnover2.4 Contractility, the Functional Link; 2.5 Kinesin and Signal Transmission; 2.6 Tip Complexes Meet Adhesion Complexes; 2.7 Focal Adhesions Influence Microtubule Dynamics; 2.8 Actin Talks Back: Tension and Microtubule Guidance; 2.9 Conclusions and Perspectives; 2.10 Acknowledgments; 2.11 References; 3 Mechanisms of Eukaryotic Chemotaxis; 3.1 Chemotaxis is a Fundamental Cellular Response; 3.2 Directional Sensing Occurs Downstream of G Protein Activation and Upstream of the Accumulation of PI(3,4,5)P(3) 327 $a3.3 Input-Output Relationships Reveal Gradient Amplification in Polarized and Unpolarized Cells3.4 Increase in Local PI(3,4,5)P(3) Precedes Actin Polymerization Responses; 3.5 Positive Feedback and the Actin Cytoskeleton May Stabilize Directional Sensing and Establish Polarity; 3.6 References; 4 Dual Location Proteins: Communication Between Cell Adhesions and the Nucleus; 4.1 Introduction; 4.2 LIM Protein Family; 4.2.1 Zyxin Subfamily; 4.2.1.1 Zyxin; 4.2.1.2 LPP (Lipoma-Prefered Partner); 4.2.1.3 Trip6; 4.2.1.4 WTIP (Wilms Tumor protein 1 Interaction Protein); 4.2.1.5 Ajuba 327 $a4.2.2 Paxillin Subfamily4.2.2.1 Paxillin; 4.2.2.2 Hic-5; 4.3 MAGUK Protein Family; 4.3.1 ZO-1; 4.3.2 ZO-2; 4.3.3 CASK; 4.4 Armadillo Repeat Protein Family; 4.4.1 ?-catenin Armadillo Repeat Subfamily; 4.4.1.1 ?-catenin; 4.4.1.2 Plakoglobin; 4.4.2 p120 Armadillo Repeat Subfamily; 4.4.2.1 p120; 4.4.2.2 ARVCF; 4.4.2.3 Plakophilins; 4.5 Other Proteins - Symplekin; 4.6 Dual Location; 4.6.1 Sequestration of Transcriptional Regulators; 4.6.2 mRNA Localization; 4.6.3 Scaffolding; 4.7 Conclusion; 4.8 Acknowledgments; 4.9 References; II Classical Examples of Cell Migration in Development 327 $a5 Cell Migration During Zebrafish Gastrulation 330 $aCell Migration matches nearly all research areas in cell and developmental biology, genetics, and biomedicine. The field shows radical progress powered by the combination of new genomic tools, cell labeling techniques and the incorporation of new model systems. This is the first book to comprehensively cover cell migration from the identification of molecular mechanisms to the understanding of certain pathological disorders and cancer development. 606 $aCell migration$xDiseases 608 $aElectronic books. 615 0$aCell migration$xDiseases. 676 $a571.6 676 $a571.8 676 $a571.835 701 $aWedlich$b Doris$0935717 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910144557503321 996 $aCell migration in development and disease$92107752 997 $aUNINA LEADER 02615nam 2200589Ia 450 001 9910781805003321 005 20230207225629.0 010 $a0-8166-5667-3 035 $a(CKB)1000000000488208 035 $a(EBL)340776 035 $a(OCoLC)476156660 035 $a(SSID)ssj0000152824 035 $a(PQKBManifestationID)11162356 035 $a(PQKBTitleCode)TC0000152824 035 $a(PQKBWorkID)10391552 035 $a(PQKB)10842835 035 $a(MiAaPQ)EBC340776 035 $a(OCoLC)229041256 035 $a(MdBmJHUP)muse39050 035 $a(Au-PeEL)EBL340776 035 $a(CaPaEBR)ebr10225516 035 $a(CaONFJC)MIL522459 035 $a(EXLCZ)991000000000488208 100 $a20070921d2008 ub 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aFacing north$b[electronic resource] $eportraits of Ely, Minnesota /$fphotographs by Andrew Goldman ; essays by Ann Goldman ; foreword by Jim Brandenburg 210 $aMinneapolis, MN $cUniversity of Minnesota Press$dc2008 215 $a1 online resource (193 p.) 300 $aDescription based upon print version of record. 311 $a0-8166-5147-7 320 $aIncludes bibliographical references. 327 $aContents; Foreword; Photographer's Preface; Acknowledgments; A Northwoods Story: Ely, Minnesota; Facing North; Green Ice; The Tinder Box; What Is in My Heart; Wild Neighbors; The Magic of It All; Notes on the Portraits 330 $aPerched on the edge of the northern woods at the gateway to the Boundary Waters Canoe Area Wilderness, Ely, Minnesota, holds special meaning for hundreds of thousands of visitors each year. But what is it like for the people who live there year-round? Ann and Andrew Goldman offer a revealing portrayal of the unique people who call Ely home. Featuring more than one hundred portraits as well as vivid essays, Facing North tells the story of life in this Northwoods community: its breathtaking beauty, surprisingly diverse character, and complex history. 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Setchell and Deborah J. Curtis$b[electronic resource] 205 $aSecond edition. 210 1$aCambridge :$cCambridge University Press,$d2011. 215 $a1 online resource (xxx, 425 pages) $cdigital, PDF file(s) 300 $aTitle from publisher's bibliographic system (viewed on 05 Oct 2015). 311 $a0-521-14213-X 311 $a0-521-19409-1 320 $aIncludes bibliographical references and index. 327 $aAn ethnoprimatological approach to interactions between human and non-human primates / Lisa Jones-Engel, Gregory A. Engel and Agustin Fuentes -- Habituating primates : processes, techniques, variables and ethics / Elizabeth A. Williamson and Anna T.C. Feistner -- Habitat description and phenology / Jo?rg U. Ganzhorn, S. Jacques Rakotondranary and Yedidya R. Ratovonamana -- Geographical information systems and remote sensing / Patrick E. Osborne and Louise Glew -- Monitoring local weather and climate / Julian C. Mayes and Nicholas Pepin -- Survey and census methods : population distribution and density / Caroline Ross and Nigel Reeve -- Trapping primates / Clifford J. Jolly, Jane E. Phillips-Conroy and Alexandra E. Mu?ller -- Handling, anaesthesia, health evaluation and biological sampling / Steve Unwin, Marc Ancrenaz and Wendi Bailey -- Morphology, morphometrics and taxonomy / Colin Groves and Joanne Harding -- Marking and radio-tracking primates / Paul E. Honess and David W. MacDonald -- Field experiments with non-human primates : a tutorial / Klaus Zuberbu?hler and Roman M. Wittig -- Feeding ecology, frugivory and seed dispersal / J. Lawrence Dew -- Dietary analysis I : food physics / Peter W. Lucas, ... [et al.] -- Dietary analysis II : food chemistry / Peter W. Lucas, ... [et al.] -- Collecting arthropods and arthropod remains for primate studies / Claire M.P. Ozanne, James R. Bell and Daniel G. Weaver -- Recording primate vocalizations / Thomas Geissmann and Stuart Parsons -- Photography and video for field researchers / Noel Rowe and Marc Myers -- Chronobiological aspects of primate research / Hans G. Erkert -- Thermoregulation and energetics / Jutta Schmid -- Field endocrinology : monitoring hormonal changes in free-ranging primates / J. Keith Hodges and Michael Heistermann -- Collection, storage and analysis of non-invasive genetic material in primate biology / Benoi?t Goossens, ... [et al.] -- Tips from the bush : and A-Z of suggestions for successful fieldwork / Simon K. Bearder and K. Anne I. Nekaris 330 $aBuilding on the success of the first edition and bringing together contributions from a range of experts in the field, the second edition of this guide to research on wild primates covers the latest advances in the field, including new information on field experiments and measuring behaviour. It provides essential information and advice on the technical and practical aspects of both field and laboratory methods, covering topics such as ethnoprimatology; remote sensing; GPS and radio-tracking; trapping and handling; dietary ecology; and non-invasive genetics and endocrinology. This integrated approach opens up new opportunities to study the behavioural ecology of some of the most endangered primates and to collect information on previously studied populations. Chapters include methodological techniques; instructions on collecting, processing and preserving samples/data for later analysis; ethical considerations; comparative costs; and further reading, making this an invaluable tool for postgraduate students and researchers in primatology, behavioural ecology and zoology. 517 3 $aField & Laboratory Methods in Primatology 606 $aPrimates$xResearch$xMethodology 606 $aPrimatology 615 0$aPrimates$xResearch$xMethodology. 615 0$aPrimatology. 676 $a599.80728 702 $aSetchell$b Joanna M.$f1973- 702 $aCurtis$b Deborah J.$f1964- 801 0$bUkCbUP 801 1$bUkCbUP 906 $aBOOK 912 $a9910785692103321 996 $aField and laboratory methods in primatology$93761062 997 $aUNINA