LEADER 06202nam 22009973u 450 001 9910781762303321 005 20210208175852.0 010 $a1-119-97695-2 010 $a1-283-24044-0 010 $a9786613240446 010 $a1-119-97696-0 035 $a(CKB)2550000000045694 035 $a(EBL)819268 035 $a(OCoLC)759006603 035 $a(SSID)ssj0000536969 035 $a(PQKBManifestationID)11359162 035 $a(PQKBTitleCode)TC0000536969 035 $a(PQKBWorkID)10552494 035 $a(PQKB)10945511 035 $a(MiAaPQ)EBC819268 035 $a(PPN)156614448 035 $a(EXLCZ)992550000000045694 100 $a20131223d2011|||| u|| | 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aFungi$b[electronic resource] $eBiology and Applications 205 $a2nd ed. 210 $aHoboken $cWiley$d2011 215 $a1 online resource (386 p.) 300 $aDescription based upon print version of record. 311 $a0-470-97709-4 311 $a0-470-97710-8 327 $aFungi; Contents; List of Contributors; 1 Introduction to Fungal Physiology; 1.1 Introduction; 1.2 Morphology of Yeasts and Fungi; 1.3 Ultrastructure and Function of Fungal Cells; 1.4 Fungal Nutrition and Cellular Biosyntheses; 1.5 Fungal Metabolism; 1.6 Fungal Growth and Reproduction; 1.7 Conclusions; Revision Questions; References; Further Reading; 2 Fungal Genetics; 2.1 Introduction; 2.2 Fungal Life Cycles; 2.3 Sexual Analysis: Regulation of Mating; 2.4 Unique Characteristics of Filamentous Fungi that are Advantageous for Genetic Analysis; 2.5 Genetics as a Tool; 2.6 Conclusion 327 $aAcknowledgementRevision Questions; References; Further Reading; 3 Fungal Genomics; 3.1 Introduction; 3.2 Genome Sequencing; 3.3 Bioinformatics Tools; 3.4 Comparative Genomics; 3.5 Genomics and the Fungal Tree of Life; 3.6 Online Fungal Genomic Resources; 3.7 Conclusion; Revision Questions; Further Reading; 4 Fungal Genetics: A Post-Genomic Perspective; 4.1 Introduction; 4.2 Genomics; 4.3 Transcriptomics and Proteomics; 4.4 Proteomics; 4.5 Systems Biology; 4.6 Conclusion; Revision Questions; References; Further Reading; 5 Fungal Fermentations Systems and Products; 5.1 Introduction 327 $a5.2 Fungal Fermentation Systems5.3 Commercial Fungal Products; 5.4 Conclusion; Revision Questions; Reference; Further Reading; 6 Pharmaceutical and Chemical Commodities from Fungi; 6.1 Introduction to Pharmaceutical and Chemical Commodities; 6.2 Fungal Metabolism; 6.3 Antibiotic Production; 6.4 Pharmacologically Active Products; 6.5 Chemical Commodities; 6.6 Yeast Extracts; 6.7 Enriched Yeast; 6.8 Conclusions; Revision Questions; References; Further Reading; 7 Biotechnological Use of Fungal Enzymes; 7.1 Introduction to Enzymes; 7.2 Enzymes in Industry; 7.3 Current Enzyme Applications 327 $a7.4 Future Direction of Industrial Enzymes7.5 Specific Enzymes; 7.6 Enzyme Production Strategies; 7.7 Conclusions; Revision Questions; References; Further Reading; 8 The Biotechnological Exploitation of Heterologous Protein Production in Fungi; 8.1 Introduction; 8.2 Heterologous Protein Expression in Fungi; 8.3 Case Study: Hepatitis B Vaccine: A Billion Dollar Heterologous Protein from Yeast; 8.4 Further Biotechnological Applications of Expression Technology; 8.5 Conclusions; Revision Questions; Further Reading; 9 Fungal Proteomics; 9.1 Introduction; 9.2 Protein Isolation and Purification 327 $a9.3 Electrophoretic Techniques9.4 Protein Mass Spectrometry; 9.5 Fungal Proteomics; 9.6 Specialized Proteomics Applications in Fungal Research; 9.7 Conclusion; Revision Questions; Further Reading; 10 Fungal Infections of Humans; 10.1 Introduction; 10.2 Superficial Mycoses; 10.3 Opportunistic Mycoses; 10.4 Endemic Systemic Mycoses; 10.5 Mycotoxicoses; 10.6 Concluding Remarks; Revision Questions; Further Reading; 11 Antifungal Agents for Use in Human Therapy; 11.1 Introduction; 11.2 Drugs Targeting the Plasma Membrane; 11.3 Drugs Targeting the Cell Wall 327 $a11.4 Drugs Targeting Nucleic Acid and Protein Synthesis 330 $aFungi: Biology and Applications, Second Edition provides a comprehensive treatment of fungi, covering biochemistry, genetics and the medical and economic significance of these organisms at introductory level. With no prior knowledge of the subject assumed, the opening chapters offer a broad overview of the basics of fungal biology, in particular the physiology and genetics of fungi and also a new chapter on the application of genomics to fungi. 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