LEADER 03130nam 2200649Ia 450 001 9910781197603321 005 20230721005643.0 010 $a1-282-05804-5 010 $a9786612058042 010 $a92-4-068747-5 035 $a(CKB)2550000000004596 035 $a(EBL)753786 035 $a(OCoLC)787842453 035 $a(SSID)ssj0000300504 035 $a(PQKBManifestationID)11196186 035 $a(PQKBTitleCode)TC0000300504 035 $a(PQKBWorkID)10252680 035 $a(PQKB)10574004 035 $a(MiAaPQ)EBC753786 035 $a(Au-PeEL)EBL753786 035 $a(CaPaEBR)ebr10277796 035 $a(CaONFJC)MIL205804 035 $a(EXLCZ)992550000000004596 100 $a20081120d2007 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aIPCS mode of action framework$b[electronic resource] /$fIPCS 210 $aGeneva, Switzerland $cWorld Health Organization$dc2007 215 $a1 online resource (130 p.) 225 1 $aHarmonization Project document ;$vno. 4 300 $a"IPCS International Programme on Chemical Safety." 300 $a"This project was conducted within the IPCS project on the Harmonization of Approaches to the Assessment of Risk from Exposure to Chemicals"--P. [i]. 300 $a"Published under the joint sponsorship of the World Health Organization, the International Labour Organization and the United Nations Environment Programme, and produced within the framework of the Inter-Oganization Programme for the Sound Management of Chemicals"--P. [i]. 311 $a92-4-156349-4 320 $aIncludes bibliographical references. 327 $aBOOK COVER; TITLE; COPYRIGHT; TABLE OF CONTENTS; FOREWORD; PART 1 IPCS FRAMEWORK FOR ANALYSING THE RELEVANCE OF A CANCER MODE OF ACTION FOR HUMANS AND CASE-STUDIES; PART 2 IPCS FRAMEWORK FOR ANALYSING THE RELEVANCE OF A NON-CANCER MODE OF ACTION FOR HUMANS 330 $aThe use of structured frameworks in chemical risk assessment promotes transparent harmonized approaches. This book presents two IPCS frameworks originally published in Critical Reviews in Toxicology in a user-friendly large format. Part 1 contains the IPCS Framework for Analysing the Relevance of a Cancer Mode of Action for Humans along with three case studies illustrating its application. Part 2 contains the IPCS Framework for Analysing the Relevance of a Non-Cancer Mode of Action for Humans. The output of a framework analysis is a clear statement of conclusions together with the confidence a 410 0$aHarmonization Project document ;?vno. 4. 606 $aHazardous substances 606 $aCarcinogens 606 $aCarcinogenicity testing 606 $aHealth risk assessment 615 0$aHazardous substances. 615 0$aCarcinogens. 615 0$aCarcinogenicity testing. 615 0$aHealth risk assessment. 676 $a616.994071 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910781197603321 996 $aIPCS mode of action framework$93689603 997 $aUNINA