LEADER 04741nam 2200661Ia 450 001 9910781086103321 005 20230721005628.0 010 $a1-282-44086-1 010 $a9786612440861 010 $a1-84816-257-X 035 $a(CKB)2550000000003540 035 $a(EBL)477135 035 $a(OCoLC)647850790 035 $a(SSID)ssj0000338410 035 $a(PQKBManifestationID)11284920 035 $a(PQKBTitleCode)TC0000338410 035 $a(PQKBWorkID)10295802 035 $a(PQKB)10082258 035 $a(MiAaPQ)EBC477135 035 $a(WSP)00000710 035 $a(Au-PeEL)EBL477135 035 $a(CaPaEBR)ebr10361671 035 $a(CaONFJC)MIL244086 035 $a(EXLCZ)992550000000003540 100 $a20080718d2009 uy 0 101 0 $aeng 135 $aurcuu|||uu||| 181 $ctxt 182 $cc 183 $acr 200 00$aHandbook of cardiac stem cell therapy$b[electronic resource] /$fedited by Ioannis Dimarakis ... [et al.] 210 $aLondon $cImperial College Press$dc2009 215 $a1 online resource (306 p.) 300 $aDescription based upon print version of record. 311 $a1-84816-256-1 320 $aIncludes bibliographical references and index. 327 $a3. Embryonic Stem Cells and Their Therapeutic Potential Tomo S?ari ?c, Shuhua Chen, Naidu Kamisseti, Marcel Halbach, Michael Xavier Doss, Johannes Winkler, Ju?rgen Hescheler and Agapios Sachinidis Embryonic Stem Cells; ES Cell-Derived Cardiomyocytes; Generation of cardiomyocytes from ES cells; Functional characteristics of ES cell-derived cardiomyocytes; Animal models of cardiomyocytes derived from ES cells; Other Animal Models for ES Cell-Based Therapeutics; Models for neural diseases; Models for therapy for type I diabetes mellitus; Animal models for liver and kidney regeneration 327 $aCell replacement therapy for other organ systems Barriers to Successful Use of ES Cell-Based Therapies; Ethical concerns; Safety concerns and purity; Rejection of allogeneic cells; Conclusions; References; 4. Umbilical Cord Blood Cells for Cardiac Repair Elad Maor, Arnon Nagler and Jonathan Leor; Introduction; Myocardial Infarction and Heart Failure; Myocardial Regeneration and Cell-Based Therapy; Problems with the Available Cell Sources; The Rationale for Using UCB Progenitor Cells for Myocardial Repair; Data from Animal Models; How Do Cord Blood Cells Repair Ischemic Tissue? 327 $aEx vivo Expansion Immunosuppression and Graft versus Host Disease; Summary; References; 5. Amniotic Stem Cells Paolo De Coppi, Anthony Atala and Saverio Sartore; Introduction; Amniocentesis; Differentiated Cells from Amniotic Fluid; Mesenchymal Stem Cells from Amniotic Fluid; Amniotic Fluid Stem Cells; Cell preparation and culture methods; Cell cloning; Telomerase activity; Differentiation potential induction of osteogenic phenotype; Induction of adipogenic lineage; Induction of myogenic phenotype; Induction of endothelial phenotype; Induction of hepatocytes phenotype 327 $aInduction of neurogenic phenotype Clonal and proliferative analyses; Conclusion; References; 6. Stem Cell Homing to Injury in Cellular Cardiomyoplasty Adil Al Kindi, Dominique Shum-Tim and Ray Chu-Jeng Chiu; Introduction; The Prelude: Insights from Bone Marrow Transplantation; Animal Studies; The Signaling Molecules; Summary and Conclusions; References; 7. A Molecular Imaging Perspective on Cardiac Repair with Stem Cells Kishore Bhakoo; Introduction; Radionuclide Imaging; Optical Imaging; Ultrasound; MRI Imaging; Intracellular MRI Contrast Agents; MRI Tracking of Stem Cells in the Heart 327 $aMultimodality 330 $aThis book is an impressive compilation of contributions on the hot topic of cardiac stem cell therapy from leading groups all over the world. In the assembly of chapters, a structured approach is adopted; starting from the clinician's perspective, all developments in both the experimental and clinical research areas are covered. This journey will take the reader from the bench-top to the bedside, with all chapters written by leading authorities in their respective fields, including data still in press with medical journals. 606 $aHeart$xDiseases$xTreatment 606 $aStem cells$xTransplantation 606 $aStem cells 615 0$aHeart$xDiseases$xTreatment. 615 0$aStem cells$xTransplantation. 615 0$aStem cells. 676 $a616.1206 676 $a616/.02774 701 $aDimarakis$b Ioannis$01561414 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910781086103321 996 $aHandbook of cardiac stem cell therapy$93828097 997 $aUNINA