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024 7 $a10.1007/0-306-46850-6
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100   $a19960515d1996      uy             0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 00$aInsect cell cultures$b[electronic resource] $efundamental and applied aspects /$fedited by J.M. Vlak ... [et al.]
205   $a1st ed. 2002.
210   $aDordrecht [Netherlands] ;$aBoston $cKluwer$dc1996
215   $a1 online resource (325 p.)
225 1 $aCurrent applications in cell culture engineering ;$vvol. 2
300   $aDescription based upon print version of record.
311   $a0-7923-3403-5 
320   $aIncludes bibliographical references and index.
327   $aInsect Cell Lines -- Development and characterization of insect cell lines -- New approaches to insect tissue culture -- Transgenic insect cells: mosquito cell mutants and the dihydrofolate reductase gene -- Insect cell physiology -- Insect cell cultivation: growth and kinetics -- Medium design for insect cell culture -- Viruses -- Baculovirus-insect cell interactions -- Replication patterns and cytopathology of cells infected with baculoviruses -- Construction of baculovirus recombinants -- Passage effect of virus infection in insect cells -- Post-translational modifications in insect cells -- Productivity of insect cells for recombinant proteins -- Chaperone and foldase coexpression in the baculovirus-insect cell expression system -- Engineering Aspects -- Shear sensitivity of insect cells -- Insect cell bioreactors -- Perfusion bioreactors for the production of recombinant proteins in insect cells -- Immobilization of insect cells -- Modelling baculovirus infection of insect cells in culture -- Scale up aspects of sparged insect-cell bioreactors -- Oxygen gradients in small and big sparged insect-cell bioreactors -- Downstream processing of insect cell cultures -- Applications -- Parvovirus diagnostics and vaccine production in insect cells -- Classical swine fever virus diagnostics and vaccine production in insect cells -- Production of multidomain complement glycoproteins in insect cells -- Economic and Regulatory Aspects -- Economics of baculovirus-insect cell production systems -- Safety aspects of insect cell culture -- Regulatory issues in the use of insect-cell culture.
410  0$aCurrent applications of cell culture engineering ;$vv. 2.
606   $aInsect cell biotechnology
606   $aInsects$xViruses
606   $aInsects$xCytology
615  0$aInsect cell biotechnology.
615  0$aInsects$xViruses.
615  0$aInsects$xCytology.
676   $a660/.6
701   $aVlak$b J. M$01531189
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910780037203321
996   $aInsect cell cultures$93776614
997   $aUNINA