LEADER 02429nam 2200577 a 450 001 9910780005003321 005 20230607213841.0 010 $a0-309-17114-8 010 $a0-309-51345-6 035 $a(CKB)111069351122094 035 $a(EBL)3375259 035 $a(SSID)ssj0000246882 035 $a(PQKBManifestationID)11186331 035 $a(PQKBTitleCode)TC0000246882 035 $a(PQKBWorkID)10194596 035 $a(PQKB)10704404 035 $a(Au-PeEL)EBL3375259 035 $a(CaPaEBR)ebr10032465 035 $a(OCoLC)923255502 035 $a(MiAaPQ)EBC3375259 035 $a(EXLCZ)99111069351122094 100 $a20010823d2001 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aSmall clinical trials$b[electronic resource] $eissues and challenges /$fCharles H. Evans, Jr. and Suzanne T. Ildstad, editors ; Committee on Strategies for Small-Number-Participant Clinical Research Trials, Board on Health Sciences Policy, Institute of Medicine 210 $aWashington, D.C. $cNational Academy Press$dc2001 215 $a1 online resource (221 p.) 225 1 $aCompass series 300 $aDescription based upon print version of record. 311 $a0-309-07333-2 320 $aIncludes bibliographical references (p. 177-200). 327 $a""Front Matter""; ""Reviewers""; ""Preface""; ""Contents""; ""Executive Summary""; ""1 Introduction""; ""2 Design of Small Clinical Trials""; ""3 Statistical Approaches to Analysis of Small Clinical Trials""; ""4 General Guidelines""; ""References""; ""Appendix A Study Methods""; ""Appendix B Glossary of Statistical and Clinical Trials Terms""; ""Appendix C Selected Bibliography on Small Clinical Trials""; ""Appendix D Committee and Staff Biographies"" 410 0$aCompass series. 606 $aClinical trials 606 $aClinical trials$zUnited States 615 0$aClinical trials. 615 0$aClinical trials 676 $a610/.72/4 701 $aEvans$b Charles H$g(Charles Hawes),$f1940-$01485117 701 $aIldstad$b Suzanne T$01485118 712 02$aInstitute of Medicine (U.S.).$bCommittee on Strategies for Small-Number-Participant Clinical Research Trials. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910780005003321 996 $aSmall clinical trials$93704085 997 $aUNINA