LEADER 05380nam 2200661Ia 450 001 9910458416503321 005 20200520144314.0 010 $a1-281-01892-9 010 $a9786611018924 010 $a0-08-053388-4 035 $a(CKB)1000000000384934 035 $a(EBL)307133 035 $a(OCoLC)162129036 035 $a(SSID)ssj0000169796 035 $a(PQKBManifestationID)12007467 035 $a(PQKBTitleCode)TC0000169796 035 $a(PQKBWorkID)10203398 035 $a(PQKB)11361927 035 $a(MiAaPQ)EBC307133 035 $a(PPN)131200429 035 $a(Au-PeEL)EBL307133 035 $a(CaPaEBR)ebr10186611 035 $a(CaONFJC)MIL101892 035 $a(EXLCZ)991000000000384934 100 $a20001128d2001 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aHeart physiology and pathophysiology$b[electronic resource] /$fedited by Nicholas Sperelakis (editor-in-chief) ... [et. al.] 205 $a4th ed. 210 $aSan Diego, Calif. ;$aLondon $cAcademic Press$d2001 215 $a1 online resource (1286 p.) 300 $aDescription based upon print version of record. 311 $a0-12-656975-4 320 $aIncludes bibliographical references and index. 327 $aFront Cover; Heart Physiology and Pathophysiology; Copyright Page; Contents; Contributors; Foreword; Preface; PART I: PUMPING ACTION AND ELECTRICAL ACTIVITY OF THE HEART; Chapter 1. Sequence of Cardiac Activation and Ventricular Mechanics; Chapter 2. Coronary Circulation and Hemodynamics; Chapter 3. Neurohumoral Control of Cardiac Function; Chapter 4. Control of Cardiac Output and its Alterations during Exercise and in Heart Failure; Chapter 5. Ultrastructure of Cardiac Muscle and Blood Vessels; Chapter 6. Excitability and Impulse Propagation 327 $aChapter 7. Electrocardiogram and Cardiac ExcitationChapter 8. Gap-Junction Channels and Healing-Over of Injury; PART II: CELLULAR ELECTROPHYSIOLOGY OF HEART AND VASCULAR SMOOTH MUSCLE; Chapter 9. Electrogenesis of the Resting Potential; Chapter 10. Cardiac Action Potentials; Chapter 11. Electrophysiology of Vascular Smooth Muscle; Chapter 12. Sodium Channels; Chapter 13. Voltage-Dependent Calcium Channels; Chapter 14. Voltage-Dependent K+ Channels; Chapter 15. Inwardly-Rectifying K+ Channels in the Heart; Chapter 16. Voltage and Calcium-Activated K+ Channels of Coronary Smooth Muscle 327 $aChapter 17. Ion Channels in Vascular Smooth MuscleChapter 18. Cardiac Pacemaker Currents; Chapter 19. Chloride Channels in Heart; Chapter 20. Regulation of Cardiac Ion Channels by Phosphorylation, Ca2+, Cytoskeleton, and Stretch; PART III: PUMPS AND EXCHANGERS; Chapter 21. Cardiac Na+/K+ Pump; Chapter 22. Cardiac Na+ -Ca2+ Exchanger: Pathophysiology and Pharmacology; Chapter 23. Na+/H+ Exchanger and pH Regulation; Chapter 24. Transport in Nucleus; Chapter 25. Sarcoplasmic Reticulum Ca2+ Transport; Chapter 26. Calcium Release from Cardiac Sarcoplasmic Reticulum; PART IV: VASCULAR ENDOTHELIUM 327 $aChapter 27. Function of Vascular EndotheliumChapter 28. Ion Channels in Vascular Endothelium; PART V: EXCITATION-CONTRACTION COUPLING AND PHARMACOMECHANICAL COUPLING; Chapter 29. Electromechanical and Pharmacomechanical Coupling in Vascular Smooth Muscle Cells; Chapter 30. Mechanisms Regulating Cardiac Myofilament Response to Calcium; Chapter 31. Vascular Smooth Muscle Contraction; PART VI: METABOLISM AND ENERGETICS; Chapter 32. Myocardial Energy Metabolism; Chapter 33. Metabolism and Energetics of Vascular Smooth Muscle; PART VII: SIGNALING SYSTEMS 327 $aChapter 34. Adrenergic Receptors in the Cardiovascular SystemChapter 35. Cardiac Action of Angiotensin II; Chapter 36. ATP and Adenosine Signal Transductions; Chapter 37. Kinase Signaling in the Cardiovascular System; Chapter 38. Calcium Signaling; Chapter 39. Diadenosine Polyphosphate Signaling in the Heart; PART VIII: DEVELOPMENTAL CHANGES AND AGING; Chapter 40. Cardiac Development and Regulation of Cardiac Transcription; Chapter 41. Developmental Changes of Ion Channels; Chapter 42. Aging of the Cardiovascular System; Chapter 43. Changes in Autonomic Responsiveness during Development 327 $aPART IX: MECHANISM OF ACTION OF CARDIOACTIVE DRUGS 330 $aHeart Physiology and Pathophysiology, 4E, provides the foundation for the scientific understanding of heart function and dysfunction, and bridges the gap between basic cardiovascular science and clinical cardiology. This comprehensive text covers all the important aspects of the heart and vascular system. The most important and relevant disorders are presented, with emphasis on the mechanisms involved. The first three editions of this book developed a reputation as the leading reference in cardiovascular science for researchers and academic cardiologists. This recent edition has bee 606 $aHeart$xPathophysiology 606 $aHeart$xPhysiology 608 $aElectronic books. 615 0$aHeart$xPathophysiology. 615 0$aHeart$xPhysiology. 676 $a612.1/7 21 701 $aSperelakis$b Nick$f1930-$0101016 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910458416503321 996 $aHeart physiology and pathophysiology$92160554 997 $aUNINA LEADER 03536oam 2200637I 450 001 9910778959003321 005 20230802004341.0 010 $a1-136-65218-3 010 $a9786613434883 010 $a1-136-65219-1 010 $a1-283-43488-1 010 $a0-203-80599-2 024 7 $a10.4324/9780203805992 035 $a(CKB)2550000000079210 035 $a(EBL)838155 035 $a(OCoLC)773565341 035 $a(SSID)ssj0000588834 035 $a(PQKBManifestationID)11364742 035 $a(PQKBTitleCode)TC0000588834 035 $a(PQKBWorkID)10655816 035 $a(PQKB)10952341 035 $a(MiAaPQ)EBC838155 035 $a(EXLCZ)992550000000079210 100 $a20180706d2012 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aAutism /$fStuart Murray 210 1$aNew York :$cRoutledge,$d2012. 215 $a1 online resource (131 p.) 225 1 $aThe Routledge series integrating science and culture 300 $aDescription based upon print version of record. 311 $a0-415-88498-5 311 $a0-415-88499-3 320 $aIncludes bibliographical references (p. 108-112) and index. 327 $aChapter 6. Conclusion: After the FactPart II: Social, Cultural, and Political Histories; Chapter 7. Autism before Modern Medicine; Chapter 8. The Development of Child Psychiatry: Kanner and Asperger; Chapter 9. Psychoanalysis, BrunoBettelheim, Parents, and Blame; Chapter 10. Organizations and Associations; Chapter 11. The Rise of Neurodiversity:Demands, Advocacy, and Legislation; Chapter 12.Cultural Representations: Outsider and Insider Accounts; Chapter 13.Conclusion: History in the Making; Part III: Major Controversies; Chapter 14. A Lack of Consensus; Chapter 15.Causing Autism 330 $a"Autism is the first book on the condition that seeks to combine medical, historical and cultural approaches to an understanding of the condition. Its purpose is to present a rounded portrayal of the ways in which autism is currently represented in the world, It focuses on three broad areas: the facts of scientific research, including new ideas surrounding research into genetics and neuroscience, as well as the details of diagnosis and therapy; the history of the condition as it developed through psychiatric approaches to the rise of parent associations, neurodiversity and autism advocacy; and the fictional and media narratives through which it is increasingly expressed in the contemporary moment. Accessible and written in clear English, Autism is designed for student audiences in English, Disability Studies, Cultural Studies, History, Sociology, and Medicine and Health, as well as medical practitioners and the general reader. Autism is a condition surrounded by misunderstanding and often defined by contestation and argument. The purpose of this book is to bring clarity to the subject of autism across the full range of its manifestations"--$cProvided by publisher. 410 0$aRoutledge series integrating science and culture. 606 $aAutism 606 $aAutism spectrum disorders 615 0$aAutism. 615 0$aAutism spectrum disorders. 676 $a362.19685882 676 $a616.85/882 676 $a616.85882 686 $aSOC026000$2bisacsh 700 $aMurray$b Stuart.$0530545 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910778959003321 996 $aAutism$93709635 997 $aUNINA