LEADER 06564nam 2200697 450 001 996212249903316 005 20230125205708.0 010 $a1-280-73984-3 010 $a9786610739844 010 $a0-470-05219-8 010 $a1-60119-504-4 010 $a0-470-05218-X 024 7 $a10.1002/0470052198 035 $a(CKB)1000000000355567 035 $a(EBL)288353 035 $a(SSID)ssj0000072058 035 $a(PQKBManifestationID)11118899 035 $a(PQKBTitleCode)TC0000072058 035 $a(PQKBWorkID)10095029 035 $a(PQKB)11265163 035 $a(MiAaPQ)EBC288353 035 $a(CaBNVSL)mat05237890 035 $a(IDAMS)0b00006481095d90 035 $a(IEEE)5237890 035 $a(OCoLC)86228637 035 $a(PPN)267789556 035 $a(EXLCZ)991000000000355567 100 $a20070326h20152007 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aGenomics and proteomics engineering in medicine and biology$b[electronic resource] /$fedited by Metin Akay 210 1$aPiscataway, New Jersey :$cIEEE Press,$dc2007. 215 $a1 online resource (317 p.) 225 1 $aIEEE press series on biomedical engineering ;$v25 300 $a"IEEE Engineering in Medicine and Biology Society, sponsor." 311 $a0-471-63181-7 320 $aIncludes bibliographical references and index. 327 $aPreface. -- Contributors. -- 1. Qualitative Knowledge Models in Functional Genomics and Proteomics (Mor Peleg, Irene S. Gabashvili, and Russ B. Altman). -- 1.1. Introduction. -- 1.2. Methods and Tools. -- 1.3. Modeling Approach and Results. -- 1.4. Discussion. -- 1.5. Conclusion. -- References. -- 2. Interpreting Microarray Data and Related Applications Using Nonlinear System Identification (Michael Korenberg). -- 2.1. Introduction. -- 2.2. Background. -- 2.3. Parallel Cascade Identification. -- 2.4. Constructing Class Predictors. -- 2.5. Prediction Based on Gene Expression Profiling. -- 2.6. Comparing Different Predictors Over the Same Data Set. -- 2.7. Concluding Remarks. -- References. -- 3. Gene Regulation Bioinformatics of Microarray Data (Gert Thijs, Frank De Smet, Yves Moreau, Kathleen Marchal, and Bart De Moor). -- 3.1. Introduction. -- 3.2. Introduction to Transcriptional Regulation. -- 3.3. Measuring Gene Expression Profiles. -- 3.4. Preprocessing of Data. -- 3.5. Clustering of Gene Expression Profiles. -- 3.6. Cluster Validation. -- 3.7. Searching for Common Binding Sites of Coregulated Genes. -- 3.8. Inclusive: Online Integrated Analysis of Microarray Data. -- 3.9. Further Integrative Steps. -- 3.10. Conclusion. -- References. -- 4. Robust Methods for Microarray Analysis (George S. Davidson, Shawn Martin, Kevin W. Boyack, Brian N. Wylie, Juanita Martinez, Anthony Aragon, Margaret Werner-Washburne, Monica Mosquera-Caro, and Cheryl Willman). -- 4.1. Introduction. -- 4.2. Microarray Experiments and Analysis Methods. -- 4.3. Unsupervised Methods. -- 4.4. Supervised Methods. -- 4.5. Conclusion. -- References. -- 5. In Silico Radiation Oncology: A Platform for Understanding Cancer Behavior and Optimizing Radiation Therapy Treatment (G. Stamatakos, D. Dionysiou, and N. Uzunoglu). -- 5.1. Philosophiae Tumoralis Principia Algorithmica: Algorithmic Principles of Simulating Cancer on Computer. -- 5.2. Brief Literature Review. -- 5.3. Paradigm of Four-Dimensional Simulation of Tumor Growth and Response to Radiation Therapy In Vivo. 327 $a5.4. Discussion. -- 5.5. Future Trends. -- References. -- 6. Genomewide Motif Identification Using a Dictionary Model (Chiara Sabatti and Kenneth Lange). -- 6.1. Introduction. -- 6.2. Unified Model. -- 6.3. Algorithms for Likelihood Evaluation. -- 6.4. Parameter Estimation via Minorization-Maximization Algorithm. -- 6.5. Examples. -- 6.6. Discussion and Conclusion. -- References. -- 7. Error Control Codes and the Genome (Elebeoba E. May). -- 7.1. Error Control and Communication: A Review. -- 7.3. Reverse Engineering the Genetic Error Control System. -- 7.4. Applications of Biological Coding Theory. -- References. -- 8. Complex Life Science Multidatabase Queries (Zina Ben Miled, Nianhua Li, Yue He, Malika Mahoui, and Omran Bukhres). -- 8.1. Introduction. -- 8.2. Architecture. -- 8.3. Query Execution Plans. -- 8.4. Related Work. -- 8.5. Future Trends. -- References. -- 9. Computational Analysis of Proteins (Dimitrios I. Fotiadis, Yorgos Goletsis, Christos Lampros, and Costas Papaloukas). -- 9.1. Introduction: Definitions. -- 9.2. Databases. -- 9.3. Sequence Motifs and Domains. -- 9.4. Sequence Alignment. -- 9.5. Modeling. -- 9.6. Classification and Prediction. -- 9.7. Natural Language Processing. -- 9.8. Future Trends. -- References. -- 10. Computational Analysis of Interactions Between Tumor and Tumor Suppressor Proteins (E. Pirogova, M. Akay, and I. Cosic). -- 10.1. Introduction. -- 10.2. Methodology: Resonant Recognition Model. -- 10.3. Results and Discussions. -- 10.4. Conclusion. -- References. -- Index. -- About the Editor. 330 $aCurrent applications and recent advances in genomics and proteomics Genomics and Proteomics Engineering in Medicine and Biology presents a well-rounded, interdisciplinary discussion of a topic that is at the cutting edge of both molecular biology and bioengineering. Compiling contributions by established experts, this book highlights up-to-date applications of biomedical informatics, as well as advancements in genomics-proteomics areas. Structures and algorithms are used to analyze genomic data and develop computational solutions for pathological understanding. Topics discussed include: . Qualitative knowledge models. Interpreting micro-array data. Gene regulation bioinformatics. Methods to analyze micro-array. Cancer behavior and radiation therapy. Error-control codes and the genome. Complex life science multi-database queries. Computational protein analysis. Tumor and tumor suppressor proteins interactions. 410 0$aIEEE Press Series on Biomedical Engineering ;$v25 606 $aProteomics 606 $aGenomics 606 $aBioinformatics 615 0$aProteomics. 615 0$aGenomics. 615 0$aBioinformatics. 676 $a572.86 676 $a572/.6 676 $a660.65 701 $aAkay$b Metin$0772085 801 0$bCaBNVSL 801 1$bCaBNVSL 801 2$bCaBNVSL 906 $aBOOK 912 $a996212249903316 996 $aGenomics and proteomics engineering in medicine and biology$91886527 997 $aUNISA LEADER 03217nam 2200649 a 450 001 9910778829203321 005 20230120042056.0 010 $a1-4696-0266-0 010 $a0-8078-7767-0 035 $a(CKB)2550000000080112 035 $a(EBL)837892 035 $a(OCoLC)773036454 035 $a(SSID)ssj0000571416 035 $a(PQKBManifestationID)11341096 035 $a(PQKBTitleCode)TC0000571416 035 $a(PQKBWorkID)10618173 035 $a(PQKB)10613561 035 $a(StDuBDS)EDZ0000245723 035 $a(MdBmJHUP)muse23391 035 $a(Au-PeEL)EBL837892 035 $a(CaPaEBR)ebr10521875 035 $a(MiAaPQ)EBC837892 035 $a(MiAaPQ)EBC4401461 035 $a(EXLCZ)992550000000080112 100 $a20110218d2011 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aVoices of the enslaved in nineteenth-century Cuba$b[electronic resource] $ea documentary history /$fGloria Garci?a Rodri?guez ; translated by Nancy L. Westrate ; foreword by Ada Ferrer 205 $a1st ed. 210 $aChapel Hill, N.C. $cUniversity of North Carolina Press$dc2011 215 $a1 online resource (241 p.) 225 1 $aLatin America in translation/en traduccio?n/em traduc?a?o 300 $aOriginally published: Me?xico : Centro de Investigaci?on Cienti?fica "Ing. Jorge L Tamayo," 1996. 311 $a0-8078-3218-9 311 $a0-8078-7194-X 320 $aIncludes bibliographical references and index. 327 $aSlavery and its legal regulation : the slave code : royal decree and instructional circular for the indies on the education, treatment, and work regimen of slaves : May 31, 1789 -- Slaveholders and the slave code : statement from Havana's ingenio owners to the king : Havana, January 19, 1790 -- Toward a new slave code -- Slavery and family life -- The plantation social network -- Solidarity in the face of injustice -- The labor relations of Coartado slaves. 330 $aPutting the voices of the enslaved front and center, Gloria Garcia Rodriguez's study presents a compelling overview of African slavery in Cuba and its relationship to the plantation system that was the economic center of the New World. A major essay by Garcia, who has done decades of archival research on Cuban slavery, introduces the work, providing a history of the development, maintenance, and economy of the slave system in Cuba, which was abolished in 1886, later than in any country in the Americas except Brazil. The second part of the book features eighty previously unpublished primary doc 410 0$aLatin America in translation/en traduccio?n/em traduc?a?o. 606 $aSlavery$zCuba$xHistory$vSources 606 $aSlavery$zCuba 615 0$aSlavery$xHistory 615 0$aSlavery 676 $a306.3/62097291 700 $aGarci?a Rodri?guez$b Gloria$01573407 701 $aWestrate$b Nancy L$01573408 701 $aFerrer$b Ada$01483612 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910778829203321 996 $aVoices of the enslaved in nineteenth-century Cuba$93849132 997 $aUNINA