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100   $a20060516d2007      uy             0
101 0 $aeng
135   $aurcn|||||||||
181   $ctxt
182   $cc
183   $acr
200 10$aGene sharing and evolution$b[electronic resource] $ethe diversity of protein functions /$fJoram Piatigorsky
210   $aCambridge, Mass. $cHarvard University Press$d2007
215   $a1 online resource (337 p.) 
300   $aBibliographic Level Mode of Issuance: Monograph
311   $a0-674-02341-2 
320   $aIncludes bibliographical references (p. 241-305) and index.
327   $tFrontmatter -- $tContents -- $tIllustrations -- $tPreface -- $t1. What Is "Gene Sharing"? -- $t2. Multifunctions and Functional Shifts: Echos from the Past -- $t3. The Elusive Concept of a "Gene" -- $t4. Eyes and Lenses: Gene Sharing by Crystallins -- $t5. The Enigmatic "Corneal Crystallins": Putative Cases of Gene Sharing -- $t6. Gene Sharing as a Common Event: Many Multifunctional Proteins -- $t7. Gene Sharing during Gene Expression -- $t8. Gene Sharing As a Dynamic Evolutionary Process: Antifreeze Proteins and Hemoglobins -- $t9. Gene Duplication and the Evolution of New Functions -- $t10. Gene Sharing and Systems Biology: Implications and Speculations -- $t11. Recapitulations: Ambiguities and Possibilities -- $tGlossary -- $tReferences -- $tIndex
330   $aIn Gene Sharing and Evolution Piatigorsky explores the generality and implications of gene sharing throughout evolution and argues that most if not all proteins perform a variety of functions in the same and in different species, and that this is a fundamental necessity for evolution.
606   $aGenetic regulation
606   $aProteins$xEvolution
606   $aEye$xMolecular aspects
606   $aCrystalline lens
615  0$aGenetic regulation.
615  0$aProteins$xEvolution.
615  0$aEye$xMolecular aspects.
615  0$aCrystalline lens.
676   $a572/.6
686   $aWG 1940$2rvk
700   $aPiatigorsky$b Joram$01512542
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910778453603321
996   $aGene sharing and evolution$93746489
997   $aUNINA