LEADER 01170nam0-2200301 --450 001 9910250954803321 005 20180129093505.0 100 $a20180129d1976----kmuy0itay5050 ba 101 0 $aita 102 $aIT 105 $a 001yy 200 1 $aClassificazione decimale universale$eclassi 622/629, industria mineraria, ingegneria militare civile idraulica sanitaria, tecnica dei mezzi di trasporto 210 $aRoma$c[s.n.]$d1976$eRoma$gTip. S. Pio X 215 $a269 p.$d25 cm 225 1 $aNote di bibliografia e di documentazione scientifica$v25 300 $aIn testa al frontespizio: Consiglio nazionale delle ricerche, Istituto di studi sulla ricerca e documentazione scientifica 610 0 $aClassificazione decimale universale 676 $a025.432$v19 676 $a025.432$v20 710 02$aInternational Federation for Documentation$4070$0131065 712 02$aIstituto di studi sulla ricerca e documentazione scientifica 801 0$aIT$bUNINA$gREICAT$2UNIMARC 901 $aBK 912 $a9910250954803321 952 $aINU B 1286$b2029$fFARBC 959 $aFARBC 996 $aClassificazione decimale universale$91504002 997 $aUNINA LEADER 04301nam 2200601 a 450 001 9910778429503321 005 20210519184633.0 010 $a1-282-39701-X 010 $a9786612397011 010 $a90-474-2214-7 035 $a(CKB)1000000000807018 035 $a(EBL)467607 035 $a(OCoLC)536021186 035 $a(SSID)ssj0000361155 035 $a(PQKBManifestationID)11249084 035 $a(PQKBTitleCode)TC0000361155 035 $a(PQKBWorkID)10349065 035 $a(PQKB)10519228 035 $a(MiAaPQ)EBC467607 035 $a(nllekb)BRILL9789047422143 035 $a(Au-PeEL)EBL467607 035 $a(CaPaEBR)ebr10359100 035 $a(CaONFJC)MIL239701 035 $a(PPN)170412245 035 $a(EXLCZ)991000000000807018 100 $a20070711d2007 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt 182 $cc 183 $acr 200 12$aA history of contemporary Chinese literature$b[electronic resource] /$fby Hong Zicheng ; translated by Michael M. Day 210 $aLeiden ;$aBoston $cBrill$d2007 215 $a1 online resource (656 p.) 225 1 $aBrill's humanities in China library,$x1874-8023 ;$vv. 1 300 $aDescription based upon print version of record. 311 $a90-04-15754-9 320 $aIncludes bibliographical references (p. [551]-572) and index. 327 $tPreliminary Material /$rZ. Hong and M.M. Day --$tChapter One. The ?transition? in literature /$rZ. Hong and M.M. Day --$tChapter Two. Literary norms and the literary environment /$rZ. Hong and M.M. Day --$tChapter Three. Contradictions and conflicts /$rZ. Hong and M.M. Day --$tChapter Four. Hidden poets and poetry groupings /$rZ. Hong and M.M. Day --$tChapter Five. The forms of poetry /$rZ. Hong and M.M. Day --$tChapter Six. Themes and forms of fiction /$rZ. Hong and M.M. Day --$tChapter Seven. Rural area fiction /$rZ. Hong and M.M. Day --$tChapter Eight. The narration of history /$rZ. Hong and M.M. Day --$tChapter Nine. The plight of other forms of fiction /$rZ. Hong and M.M. Day --$tChapter Ten. Beyond the mainstream /$rZ. Hong and M.M. Day --$tChapter Eleven. Prose /$rZ. Hong and M.M. Day --$tChapter Twelve. The theater /$rZ. Hong and M.M. Day --$tChapter Thirteen. Towards ?cultural revolution literature? /$rZ. Hong and M.M. Day --$tChapter fourteen. The re-construction of classics /$rZ. Hong and M.M. Day --$tChapter Fifteen. A divided literary world /$rZ. Hong and M.M. Day --$tChapter Sixteen. The literary environment during the 1980's /$rZ. Hong and M.M. Day --$tChapter Seventeen. A survey of 1980's literature /$rZ. Hong and M.M. Day --$tChapter Eighteen. Fiction during the first half of the 1980's /$rZ. Hong and M.M. Day --$tChapter Nineteen. 1980's poetry /$rZ. Hong and M.M. Day --$tChapter Twenty. The new poetry tide /$rZ. Hong and M.M. Day --$tChapter twenty-one. Fiction of the second half of the 1980's (A) /$rZ. Hong and M.M. Day --$tChapter twenty-two. Fiction of the second half of the 1980's (B) /$rZ. Hong and M.M. Day --$tChapter Twenty-Three. The art of woman writers /$rZ. Hong and M.M. Day --$tChapter Twenty-Four. The art of prose /$rZ. Hong and M.M. Day --$tChapter Twenty-Five. The situation of literature in the 1990's /$rZ. Hong and M.M. Day --$tA chronology of contemporary literature in china /$rZ. Hong and M.M. Day --$tPostscript /$rZ. Hong and M.M. Day --$tGlossary of terms, organizations, and periodicals /$rZ. Hong and M.M. Day --$tBibliography /$rZ. Hong and M.M. Day --$tTitles of works cited /$rZ. Hong and M.M. Day --$tIndex /$rZ. Hong and M.M. Day. 330 $a"A thorough overview and analysis of the literary scene in China during the 1949-1999 period, focusing primarily on fiction, poetry, drama, and prose writing"--Provided by publisher. 410 0$aBrill's humanities in China library ;$vv. 1. 606 $aChinese literature$y20th century$xHistory and criticism 615 0$aChinese literature$xHistory and criticism. 676 $a895.1/09005 700 $aHong$b Zicheng$0673707 701 $aDay$b Michael M$01552386 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910778429503321 996 $aA history of contemporary Chinese literature$93812237 997 $aUNINA LEADER 05513nam 2200637 450 001 9910821292903321 005 20230807213534.0 010 $a1-910190-02-0 035 $a(CKB)3710000000355113 035 $a(EBL)1977390 035 $a(SSID)ssj0001467634 035 $a(PQKBManifestationID)11872181 035 $a(PQKBTitleCode)TC0001467634 035 $a(PQKBWorkID)11518573 035 $a(PQKB)10133086 035 $a(MiAaPQ)EBC1977390 035 $a(MiAaPQ)EBC5897869 035 $a(Au-PeEL)EBL5897869 035 $a(OCoLC)904518422 035 $a(EXLCZ)993710000000355113 100 $a20191016d2015 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aAntifungals $efrom genomics to resistance and the development of novel agents /$fedited by Alix T. Coste, Institute of Microbiology, University Hospital Lausanne, and University Hospital Center, Lausanne, Switzerland, and Patrick Vandeputte, Host-Pathogen Interactions Study Group, UPRES-EA 3142, L'UNAM Angers University, and Parasitology-Mycology Laboratory, University Hospital Center, Angers, France 210 1$aNorfolk, England :$cCaister Academic Press,$d[2015] 210 4$dİ2015 215 $a1 online resource (346 p.) 300 $aDescription based upon print version of record. 311 $a1-910190-01-2 320 $aIncludes bibliographical references (some color) and index. 327 $aContents; Contributors; Preface; 1: Molecular Mechanisms of Resistance of Candida spp. to Membrane-targeting Antifungals; Introduction; Azoles; Non-azole ergosterol biosynthesis inhibitors; Polyenes; Concluding remarks; 2: Point Mutations and Membrane-targeting Antifungal Resistance in Aspergillus fumigatus and Other Non-Candida Species; Introduction; Aspergillus fumigatus azole resistance in clinical settings; The molecular target of azoles, allylamines and polyenes: ergosterol and ergosterol biosynthesis pathway; Differences in ergosterol pathway between Aspergillus spp. and yeasts 327 $aFungal 14-a sterol demethylases (SDMs): the main target for azole antifungalsA. fumigatus azole susceptibility patterns and mechanisms of azole resistance linked with CYP51 point mutations; Azole resistance in non-fumigatus Aspergillus; Azole secondary resistance linked with point mutations in the 14-? sterol demethylase enzyme in non-Candida and non-Aspergillus species; Polyene resistance; Resistance to allylamines; General conclusion; 3: Echinocandins: Resistance Mechanisms; Introduction; Structures; Echinocandin target: Fks1; Fks gene family; Fks1 structure-function 327 $aCell-free ?-1,3-glucan synthase systemsEchinocandin uptake and efflux; Acquired echinocandin resistance: Fks hot spots 1 and 2; Differential echinocandin resistance: discovery of hot spot 3; Impact of Fks heterozygosity and redundancy on acquired resistance; Fks-independent acquired echinocandin resistance; Intrinsic echinocandin resistance: hot spot 1 substitutions; Intrinsic echinocandin resistance: hot spot 3 substitutions; Intrinsic resistance: mechanism to be determined; Stage-specific intrinsic resistance; Conclusions and future prospects; 4: Biofilms and Antifungal Resistance 327 $aIntroduction to fungal biofilmsFungal biofilm infections of humans; Current standard of care for fungal biofilm infections; Mechanisms of fungal biofilm drug resistance; Challenges and strategies to developing therapeutics for fungal biofilm infections; 5: Drug Combinations as a Strategy to Potentiate Existing Antifungal Agents; Introduction; In vitro and in vivo combinations with known antifungal agents; In vitro and in vivo combinations of non-antifungals with known antifungal agents; Systematic drug combination screenings 327 $aChemogenetic approaches in the exploration of drug interaction mechanismsConclusions; 6: Approaches to Detect Alternative Mechanisms of Resistance to Systemic Antifungals; Introduction; 'Omics' approaches; Mutants collections screening; Comparison with others species; Concluding remarks; 7: New Antifungal Discovery from Existing Chemical Compound Collections; Introduction; A new career for acetylsalicylic acid as an antifungal; Other non-traditional antimicrobial agents; Conclusion and future perspectives; 8: Exploring New Insights into Fungal Biology as Novel Antifungal Drug Targets 327 $aIntroduction 330 $aInfections caused by pathogenic fungi are a significant global problem; a situation exacerbated by the limited availability of good antifungal options. Being eukaryotic organisms, these pathogens are phylogenetically much closer to the human host than bacterial pathogens. This sets serious limits to the range of exploitable fungal-specific drug targets. The advent of 'omics' and other high throughput technologies in recent years has revolutionized the field of antifungal research permitting researchers to quickly identify novel compounds and gain greater insights into drug resistance mechanism 606 $aImmunotherapy 606 $aAntifungal agents 606 $aBiofilms 615 0$aImmunotherapy. 615 0$aAntifungal agents. 615 0$aBiofilms. 676 $a616.969061 702 $aCoste$b Alix T. 702 $aVandeputte$b Patrick$f1979- 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910821292903321 996 $aAntifungals$94081074 997 $aUNINA