LEADER 03902oam 22006374a 450 001 9910778348303321 005 20231101221706.0 010 $a0-8018-8936-7 035 $a(CKB)1000000000482243 035 $a(OCoLC)232160429 035 $a(CaPaEBR)ebrary10188465 035 $a(SSID)ssj0000262512 035 $a(PQKBManifestationID)11220704 035 $a(PQKBTitleCode)TC0000262512 035 $a(PQKBWorkID)10269993 035 $a(PQKB)10221284 035 $a(MiAaPQ)EBC3318266 035 $a(Au-PeEL)EBL3318266 035 $a(CaPaEBR)ebr10188465 035 $a(OCoLC)923192431 035 $a(EXLCZ)991000000000482243 100 $a20050727d2006 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 14$aThe troubled dream of genetic medicine $eethnicity and innovation in Tay-Sachs, cystic fibrosis, and sickle cell disease /$fKeith Wailoo and Stephen Pemberton 210 1$aBaltimore :$cJohns Hopkins University Press,$d2006. 215 $a1 online resource (viii, 249 pages) 300 $aBibliographic Level Mode of Issuance: Monograph 311 0 $a0-8018-8326-1 311 0 $a0-8018-8325-3 320 $aIncludes bibliographical references (p. [175]-222) and index. 327 $aEthnic symbols in conflicted times Eradicating a "Jewish gene": promises and pitfalls in the fight against Tay-Sachs disease Risky business in white America: gene therapy and other ventures in the treatment of cystic fibrosis A perilous lottery for the Black family: sickle cells, social justice, and the new therapeutic gamble Dreams amid diversity 330 $aWhy do racial and ethnic controversies become attached, as they often do, to discussions of modern genetics? How do theories about genetic difference become entangled with political debates about cultural and group differences in America? Such issues are a conspicuous part of the histories of three hereditary diseases: Tay-Sachs, commonly identified with Jewish Americans; cystic fibrosis, often labeled a "Caucasian" disease; and sickle cell disease, widely associated with African Americans. In this captivating account, historians Keith Wailoo and Stephen Pemberton reveal how these diseases - fraught with ethnic and racial meanings for many Americans - became objects of biological fascination and crucibles of social debate. Peering behind the headlines of breakthrough treatments and coming cures, they tell a complex story: about different kinds of suffering and faith, about unequal access to the promises and perils of modern medicine, and about how Americans consume innovation and how they come to believe in, or resist, the notion of imminent medical breakthroughs. With Tay-Sachs, cystic fibrosis, and sickle cell disease as a powerful backdrop, the authors provide a glimpse into a diverse America where racial ideologies, cultural politics, and conflicting beliefs about the power of genetics shape disparate health care expectations and experiences. 606 $aGenetic disorders$xResearch$xMoral and ethical aspects 606 $aEthnic groups$xDiseases 606 $aTay-Sachs disease$xGenetic aspects 606 $aCystic fibrosis$xGenetic aspects 606 $aSickle cell anemia$xGenetic aspects 615 0$aGenetic disorders$xResearch$xMoral and ethical aspects. 615 0$aEthnic groups$xDiseases. 615 0$aTay-Sachs disease$xGenetic aspects. 615 0$aCystic fibrosis$xGenetic aspects. 615 0$aSickle cell anemia$xGenetic aspects. 676 $a616/.042 700 $aWailoo$b Keith$0916256 701 $aPemberton$b Stephen Gregory$01540728 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910778348303321 996 $aThe troubled dream of genetic medicine$93821698 997 $aUNINA