LEADER 06170nam 2201057 a 450 001 9910777956003321 005 20230617042828.0 010 $a1-282-35762-X 010 $a9786612357626 010 $a0-520-93151-3 024 7 $a10.1525/9780520931510 035 $a(CKB)1000000000766121 035 $a(EBL)470882 035 $a(OCoLC)609849990 035 $a(SSID)ssj0000298927 035 $a(PQKBManifestationID)11196043 035 $a(PQKBTitleCode)TC0000298927 035 $a(PQKBWorkID)10236004 035 $a(PQKB)10479290 035 $a(MiAaPQ)EBC470882 035 $a(DE-B1597)520722 035 $a(DE-B1597)9780520931510 035 $a(Au-PeEL)EBL470882 035 $a(CaPaEBR)ebr10676252 035 $a(EXLCZ)991000000000766121 100 $a20040318d2004 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt 182 $cc 183 $acr 200 10$aHow the cows turned mad$b[electronic resource] $eunlocking the mysteries of mad cow disease /$fMaxime Schwartz ; translated by Edward Schneider ; with a new foreword by Marion Nestle 210 $aBerkeley $cUniversity of California Press$d2004 215 $a1 online resource (260 p.) 300 $aDescription based upon print version of record. 311 $a0-520-24337-4 320 $aIncludes bibliographical references and index. 327 $tFront matter --$tCONTENTS --$tFOREWORD TO THE PAPERBACK EDITION --$tPROLOGUE --$t1: THE SHEEP ARE STRANGELY DIZZY --$t2: MOLECULES AND MICROBES --$t3: MAO DOGS AND EARTHWORMS --$t4: SCRAPIE UNDER THE MICROSCOPE --$t5: CREUTZFELOT, JAKOB, AND OTHERS --$t6: SCRAPIE IS INOCULABLE --$t7: AND GOATS, AND MICE --$t8: SCRAPIE IS CONTAGIOUS --$t9: KURU AND THE FORE PEOPLE OF PAPUA NEW GUINEA --$t10: THE WALL COMES DOWN --$t11: FROM PEARL NECKLACE TO DOUBLE HELIX --$t12: THE PHANTOM VIRUS --$t13: A TRAGEDY I N THE MAKING --$t14: ONE CASE PER MILLION --$t15: PRIONS --$t16: APRIL 1985 --$t17: THE "KISS OF DEATH" --$t18: THE RETURN OF THE SPONTANEISTS --$t19: TO GROW-AND TO DIE --$t20: LESSONS LEARNED --$t21: HAVE THE COWS GONE MAD? --$t22: FROM COWS TO HUMANS --$t23: FROM COWS TO SHEEP? FROM HUMANS TO HUMANS? --$t24: THE SECRET IN THE CLOSET --$t25: UNMASKING "THE DISEASE" --$t26: HAVE WE CONllUERED "THE DISEASE"? --$t27: 2001 --$tEPILOGUE --$tNOTES --$tBIBLIOGRAPHY --$tCHRONOLOGY --$tACKNOWLEDGMENTS --$tINDEX 330 $aFear of mad cow disease, a lethal illness transmitted from infected beef to humans, has spread from Europe to the United States and around the world. Originally published to much acclaim in France, this scientific thriller, available in English for the first time and updated with a new chapter on developments in 2001, tells of the hunt for the cause of an enigmatic class of fatal brain infections, of which mad cow disease is the latest incarnation. In gripping, nontechnical prose, Maxime Schwartz details the deadly manifestations of these diseases throughout history, describes the major players and events that led to discoveries about their true nature, and outlines our current state of knowledge. The book concludes by addressing the question we all want answered: should we be afraid? The story begins in the eighteenth century with the identification of a mysterious illness called scrapie that was killing British sheep. It was not until the 1960's that scientists understood that several animal and human diseases, including scrapie, were identical, and together identified them as transmissible spongiform encephalopathy (TSE). The various guises assumed throughout history by TSE include an illness called kuru in a cannibalistic tribe in Papua New Guinea, an infectious disease that killed a group of children who had been treated for growth hormone deficiencies, and mad cow disease. Revealing the fascinating process of scientific discovery that led to our knowledge of TSE, Schwartz relates pivotal events in the history of biology, including the Pasteurian revolution, the birth of genetics, the emergence of molecular biology, and the latest developments in biotechnology. He also explains the Nobel Prize-winning prion hypothesis, which has rewritten the rules of biological heredity and is a key link between the distinctive diseases of TSE. Up-to-date, informative, and thoroughly captivating, How the Cows Turned Mad tells the story of a disease that continues to elude on many levels. Yet science has come far in understanding its origins, incubation, and transmission. This authoritative book is a stunning case history that illuminates the remarkable progression of science. 606 $aBovine spongiform encephalopathy 606 $aPrion diseases in animals$xHistory 610 $aagriculture. 610 $abeef. 610 $abiology. 610 $abrain infection. 610 $acannibalism. 610 $acarnism. 610 $acarnivore. 610 $acattle. 610 $acows. 610 $adisease. 610 $afood and culture. 610 $afood studies. 610 $afood. 610 $agenetics. 610 $ahealth. 610 $aheredity. 610 $ainfectious disease. 610 $akuru. 610 $alife sciences. 610 $amad cow. 610 $amammals. 610 $ameat eating. 610 $ameat. 610 $amedical nonfiction. 610 $amedical science. 610 $amedicine. 610 $amolecular biology. 610 $aneuroscience. 610 $anonfiction. 610 $apapua new guinea. 610 $apasteur. 610 $aprion disease. 610 $aprion hypothesis. 610 $ascience. 610 $ascrapie. 610 $asheep. 610 $atransmissible spongiform encephalopathy. 610 $atse. 610 $azoology. 615 0$aBovine spongiform encephalopathy. 615 0$aPrion diseases in animals$xHistory. 676 $a616.8/3 700 $aSchwartz$b Maxime$f1940-$01548712 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910777956003321 996 $aHow the cows turned mad$93805928 997 $aUNINA LEADER 02325nam 2200397 450 001 9910812519503321 005 20230807203147.0 010 $a3-8325-9501-5 035 $a(CKB)4340000000244071 035 $a(MiAaPQ)EBC5231160 035 $a58a1c68b-a4bc-40ae-b93d-3edeb0dd2d03 035 $a(EXLCZ)994340000000244071 100 $a20180523d2015 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 12$aA general framework for robust analysis and control $ean integral quadratic constraint based approach /$fJoost Veenman 210 1$aBerlin :$cLogos Verlag Berlin,$d[2015] 210 4$dİ2015 215 $a1 online resource (275 pages) 300 $aPublicationDate: 20150420 311 $a3-8325-3963-8 330 $aLong description: In this thesis we are concerned with the robustness analysis and control of uncertain systems. We built upon a powerful framework, the so-called integral quadratic constraint (IQC) approach, which enables us, not only to efficiently perform robust stability and performance analysis for a large class of uncertain systems, but also to systematically design robust controllers via solving linear matrix inequalities (LMIs) and convex optimization problems. Indeed, as main contribution, we reveal that the IQC-framework is not only useful for analysis purposes, but also has great potential for a rather diverse class of synthesis questions, some of which have already been addressed in the literature, while others have not. This includes scenarios such as nominal output feedback control, nominal gain-scheduling control, robust estimator or observer design, robust feedforward control, generalized l2-synthesis, multi-objective and structured controller synthesis, robust open-loop controller synthesis, gain-scheduling control with uncertain performance weights and robust controller synthesis with unstable weight, among others. 606 $aRobust control 615 0$aRobust control. 676 $a629.8312 700 $aVeenman$b Joost$01721348 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910812519503321 996 $aA general framework for robust analysis and control$94120885 997 $aUNINA