LEADER 03842nam 2200673 450 001 9910777829403321 005 20221224005820.0 010 $a1-281-72210-3 010 $a9786611722104 010 $a0-300-13037-6 024 7 $a10.12987/9780300130379 035 $a(CKB)1000000000472159 035 $a(StDuBDS)AH23049666 035 $a(SSID)ssj0000134207 035 $a(PQKBManifestationID)11147962 035 $a(PQKBTitleCode)TC0000134207 035 $a(PQKBWorkID)10053919 035 $a(PQKB)10270346 035 $a(MiAaPQ)EBC3419893 035 $a(DE-B1597)484852 035 $a(OCoLC)952732295 035 $a(DE-B1597)9780300130379 035 $a(Au-PeEL)EBL3419893 035 $a(CaPaEBR)ebr10167943 035 $a(CaONFJC)MIL172210 035 $a(OCoLC)923588284 035 $a(MiAaPQ)EBC7021950 035 $a(Au-PeEL)EBL7021950 035 $a(EXLCZ)991000000000472159 100 $a20221224d2005 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt 182 $cc 183 $acr 200 14$aThe Cutter incident $ehow America's first polio vaccine led to the growing vaccine crisis /$fPaul A. Offit 210 1$aNew Haven, Connecticut :$cYale University Press,$d[2005] 210 4$dİ2005 215 $a1 online resource (256 p.) 300 $aBibliographic Level Mode of Issuance: Monograph 311 0 $a0-300-10864-8 320 $aIncludes bibliographical references (pages [225]-227) and index. 327 $tFront matter --$tContents --$tPrologue --$tIntroduction --$tChapter 1. Little White Coffins --$tChapter 2. Back to the Drawing Board --$tChapter 3. The Grand Experiment --$tChapter 4. How Does It Feel to Be a Killer of Children? --$tChapter 5. A Man-Made Polio Epidemic --$tChapter 6. What Went Wrong at Cutter Laboratories --$tChapter 7. Cutter in Court --$tChapter 8. Cigars, Parasites, and Human Toes --$tChapter 9. Death for the Lambs --$tEpilogue --$tNotes --$tSelected Bibliography --$tAcknowledgments --$tIndex 330 $aVaccines have saved more lives than any other single medical advance. Yet today only four companies make vaccines, and there is a growing crisis in vaccine availability. Why has this happened? This remarkable book recounts for the first time a devastating episode in 1955 at Cutter Laboratories in Berkeley, California, that has led many pharmaceutical companies to abandon vaccine manufacture. Drawing on interviews with public health officials, pharmaceutical company executives, attorneys, Cutter employees, and victims of the vaccine, as well as on previously unavailable archives, Dr. Paul Offit offers a full account of the Cutter disaster. He describes the nation's relief when the polio vaccine was developed by Jonas Salk in 1955, the production of the vaccine at industrial facilities such as the one operated by Cutter, and the tragedy that occurred when 200,000 people were inadvertently injected with live virulent polio virus: 70,000 became ill, 200 were permanently paralyzed, and 10 died. Dr. Offit also explores how, as a consequence of the tragedy, one jury's verdict set in motion events that eventually suppressed the production of vaccines already licensed and deterred the development of new vaccines that hold the promise of preventing other fatal diseases. 606 $aPoliomyelitis$xVaccination$zUnited States$xHistory 606 $aVaccines$zUnited States 606 $aPoliomyelitis vaccine$xHistory 615 0$aPoliomyelitis$xVaccination$xHistory. 615 0$aVaccines 615 0$aPoliomyelitis vaccine$xHistory. 676 $a614.5490973 700 $aOffit$b Paul A.$0866942 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910777829403321 996 $aThe Cutter incident$93848678 997 $aUNINA