LEADER 04018oam 22007814a 450 001 9910777516703321 005 20190503073334.0 010 $a0-262-25706-8 010 $a1-282-09679-6 010 $a9786612096792 010 $a1-4237-7254-7 035 $a(CKB)1000000000461545 035 $a(EBL)3338535 035 $a(SSID)ssj0000254896 035 $a(PQKBManifestationID)11191653 035 $a(PQKBTitleCode)TC0000254896 035 $a(PQKBWorkID)10209040 035 $a(PQKB)10290000 035 $a(StDuBDS)EDZ0000130826 035 $a(CaBNVSL)mat06267344 035 $a(IDAMS)0b000064818b4332 035 $a(IEEE)6267344 035 $a(OCoLC)68816342$z(OCoLC)182530572$z(OCoLC)473746717$z(OCoLC)648224453$z(OCoLC)655188713$z(OCoLC)704103076$z(OCoLC)888573911$z(OCoLC)961526465$z(OCoLC)962598445$z(OCoLC)988420642$z(OCoLC)992036296$z(OCoLC)1037506181$z(OCoLC)1037911808$z(OCoLC)1038673673$z(OCoLC)1083558586 035 $a(OCoLC-P)68816342 035 $a(MaCbMITP)6604 035 $a(Au-PeEL)EBL3338535 035 $a(CaPaEBR)ebr10173591 035 $a(CaONFJC)MIL209679 035 $a(OCoLC)815776335 035 $a(MiAaPQ)EBC3338535 035 $a(PPN)261608673 035 $a(EXLCZ)991000000000461545 100 $a20060515d2006 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aSystem modeling in cell biology $efrom concepts to nuts and bolts /$fedited by Zoltan Szallasi, Jo?rg Stelling, Vipul Periwal 210 $aCambridge, Mass. $cMIT Press$dİ2006 215 $a1 online resource (465 p.) 300 $a"A Bradford book." 311 $a0-262-19548-8 320 $aIncludes bibliographical references (p. [385]-433) and index. 327 $aContents; Preface; I GENERAL CONCEPTS; 1 The Role of Modeling in Systems Biology; 2 Complexity and Robustness of Cellular Systems; 3 On Modules and Modularity; II MODELING APPROACHES; 4 Bayesian Inference of Biological Systems: The Logic of Biology; 5 Stoichiometric and Constraint-based Modeling; 6 Modeling Molecular Interaction Networks with Nonlinear Ordinary Differential Equations; 7 Qualitative Approaches to the Analysis of Genetic Regulatory Networks; 8 Stochastic Modeling of Intracellular Kinetics; 9 Kinetics in Spatially Extended Systems; III MODELS AND REALITY 327 $a10 Biological Data Acquisition for System Level Modeling-An Exercise in the Art of Compromise11 Methods to Identify Cellular Architecture and Dynamics from Experimental Data; 12 Using Control Theory to Study Biology*; 13 Synthetic Gene Regulatory Systems; 14 Multilevel Modeling in Systems Biology: From Cells to Whole Organs; IV COMPUTATIONAL MODELING; 15 Computational Constraints on Modeling in Systems Biology; 16 Numerical Simulation for Biochemical Kinetics; 17 Software Infrastructure for Effective Communication and Reuse of Computational Models; A Software Tools for Biological Modeling 327 $aReferencesContributors; Index 330 8 $aThis is an introduction and overview of system modelling in biology that is accessible to researchers from different fields including biology, computer science, mathematics, statistics physics, and biochemistry. 517 1 $aSystem modeling in cellular biology 606 $aCytology$xData processing 606 $aCytology$xMathematical models 606 $aCytology$xComputer simulation 606 $aBiological systems 610 $aBIOMEDICAL SCIENCES/Quantitative Biology 615 0$aCytology$xData processing. 615 0$aCytology$xMathematical models. 615 0$aCytology$xComputer simulation. 615 0$aBiological systems. 676 $a571.601/1 701 $aSzallasi$b Zoltan$01467526 701 $aStelling$b Jo?rg$01467527 701 $aPeriwal$b Vipul$01467528 801 0$bOCoLC-P 801 1$bOCoLC-P 906 $aBOOK 912 $a9910777516703321 996 $aSystem modeling in cell biology$93678204 997 $aUNINA