LEADER 04878nam 22005773 450 001 9910772097003321 005 20220528060209.0 010 $a9781003024941 010 $a1003024947 010 $a9781000567410 010 $a1000567419 010 $a9781000567366 010 $a1000567362 024 7 $a10.1201/9781003024941 035 $a(MiAaPQ)EBC6998388 035 $a(Au-PeEL)EBL6998388 035 $a(CKB)22893540700041 035 $a(NjHacI)9922893540700041 035 $a(ScCtBLL)22fa0513-0b20-4ede-b742-30450b07ab48 035 $a(OCoLC)1323254453 035 $a(EXLCZ)9922893540700041 100 $a20220528d2022 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aHandbook of Genetic Diagnostic Technologies in Reproductive Medicine $eImproving Patient Success Rates and Infant Health 205 $a2nd ed. 210 1$aMilton :$cTaylor & Francis Group,$d2022. 210 4$d©2022. 215 $a1 online resource (480 pages) 311 08$a9780367457181 311 08$a0367457180 320 $aIncludes bibliographical references and index. 327 $aCover -- Title Page -- Copyright Page -- Table of Contents -- Contributors -- Preface -- Chapter 1 The Brave New World of Genomics -- Chapter 2 Genetics at the Cell Level: The Human Cell Atlas -- Chapter 3 The Genetic Risk of a Couple Aiming to Conceive -- Chapter 4 Carrier Screening for Single-Gene Disorders -- Chapter 5 Meiotic Abnormalities in Infertile Males -- Chapter 6 Chromosomal Analysis of Sperm -- Chapter 7 Epigenetics in Sperm, Epigenetic Diagnostics, and Transgenerational Inheritance -- Chapter 8 Aneuploidy in Human Oocytes and Preimplantation Embryos -- Chapter 9 Epigenetics from Oocytes to Embryos -- Chapter 10 Embryo Kinetics and Aneuploidy -- Chapter 11 Preimplantation Genetic Testing of Aneuploidies (PGT-A) -- Chapter 12 Preimplantation Genetic Testing for Structural Rearrangements -- Chapter 13 Mosaicism in Preimplantation Embryos -- Chapter 14 Embryo Cell-Free DNA in the Culture Medium and Its Potential for Non-Invasive Aneuploidy Testing -- Chapter 15 Mitochondria and Embryo Viability -- Chapter 16 Preimplantation Genetic Diagnosis for Single Gene Disorders -- Chapter 17 Preimplantation Genetic Testing for Polygenic Disorders -- Chapter 18 Should Genome Editing Replace Embryo Selection Following PGT? -- Chapter 19 Molecular Diagnosis of Endometrial Receptivity -- Chapter 20 The Vaginal Microbiome -- Chapter 21 The Uterine Microbiota -- Chapter 22 Endometritis: New Times, New Opportunities -- Chapter 23 Decidualization Resistance: A New Condition Identified in Severe Preeclampsia -- Chapter 24 Advanced Cell Therapy for Asherman's Syndrome -- Chapter 25 Differential Genetic Diagnosis between Leiomyoma and Leiomyosarcoma -- Chapter 26 Non-Invasive Prenatal Testing (NIPT) -- Chapter 27 Advances in Non-Invasive Diagnosis of Single-Gene Disorders and Fetal Exome Sequencing. 327 $aChapter 28 Chromosome Abnormalities in Human Pregnancy Loss: A Review of Cytogenetic and Molecular Analyses -- Chapter 29 Products of Conception: Current Methodologies and Clinical Applications -- Chapter 30 Mother and Embryo Cross Communication during Conception -- Chapter 31 Perinatal and Pediatric Outcome of Pregnancies Following PGT-M/SR/A -- Chapter 32 Genetic Counseling in Assisted Reproductive Technology -- Index. 330 $aDifferent genetic diagnostic and treatment options are used worldwide to improve routine IVF procedures for the benefit of patients. This handbook updates the new genetic diagnostic technologies that have been translated to the clinic, aiming to improve outcomes in the clinic and result in a healthy baby in the home. Chapters cover the use of genetic technologies in a personalized manner to unravel the possible genetic risks for the couple wishing to conceive, in terms of sperm, the embryo, the endometrium, miscarriage, and finally the fetus. This expanded new edition covers the range of the latest genetic diagnostic technologies being translated into practice internationally to improve routine IVF procedures for the benefit of patients. Bringing together international experts to discuss their work, this text gives a context for the developments in this very fast-moving area of research and offers a comprehensive and rounded appraisal of hot topics. 606 $aPrenatal diagnosis 615 0$aPrenatal diagnosis. 676 $a618.1/78042 676 $a618.178042 700 $aSimón$b Carlos$01242032 701 $aRubio$b Carmen$01461497 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910772097003321 996 $aHandbook of Genetic Diagnostic Technologies in Reproductive Medicine$93669428 997 $aUNINA