LEADER 03661nam 22006975 450 001 9910768201003321 005 20251009095241.0 010 $a981-9965-07-1 024 7 $a10.1007/978-981-99-6507-6 035 $a(MiAaPQ)EBC30825221 035 $a(Au-PeEL)EBL30825221 035 $a(DE-He213)978-981-99-6507-6 035 $a(PPN)272915912 035 $a(CKB)28551868400041 035 $a(EXLCZ)9928551868400041 100 $a20231024d2023 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aTheranostic Iron-Oxide Based Nanoplatforms in Oncology $eSynthesis, Metabolism, and Toxicity for Simultaneous Imaging and Therapy /$fby Mohammad-Nabil Savari, Ali Jabali 205 $a1st ed. 2023. 210 1$aSingapore :$cSpringer Nature Singapore :$cImprint: Springer,$d2023. 215 $a1 online resource (416 pages) 225 1 $aNanomedicine and Nanotoxicology,$x2194-0460 311 08$aPrint version: Savari, Mohammad-Nabil Theranostic Iron-Oxide Based Nanoplatforms in Oncology Singapore : Springer,c2023 9789819965069 320 $aIncludes bibliographical references. 327 $aIntroduction -- Drug conjugation chemistry in iron oxide nanoparticles (IONPs) -- Superparamagnetic iron oxide nanoparticle (SPION) Synthesis -- Properties of Iron oxide nanoparticles (IONPs) -- Pharmacokinetics of IONPs -- Magnetic Nanoparticles in Stimuli-Responsive Drug Delivery Systems -- IONPs-based treatment methods -- Diagnosis -- Biosensing -- Bioassays Based on Magnetic Phenomena -- Cytotoxicity/toxicity -- Coatings -- Concluding remarks and future perspectives. 330 $aThis book highlights the most efficient and latest ways to deal with cancer, focusing on IONPs. The book describes some well-designed surface modifications performed through several functional materials over the surface of IONPs, which results in the development of multifunctional IONPs-based delivery nanoplatforms by enhancing solubility, stability, and avoiding side effects on healthy cells. Several types of stimuli-responsive IONPs-based strategies are also discussed. Owing to magnetic, structural, and thermal properties, IONPs themselves can be utilized for magnetic targeting, magnetic hyperthermia, and phototherapy. Significant advancements are presented in IONPs-based immunotherapy, radiotherapy, and sonodynamic therapy for the efficient treatment of cancer. Finally, the book presents RIONs which serve as the parent platform for the development of powerful DMCAs utilized in SPECT/MRI and PET/MRI applications. 410 0$aNanomedicine and Nanotoxicology,$x2194-0460 606 $aMedical physics 606 $aCancer$xImaging 606 $aNanochemistry 606 $aNanotechnology 606 $aBiophysics 606 $aMedical Physics 606 $aCancer Imaging 606 $aNanochemistry 606 $aNanoengineering 606 $aBioanalysis and Bioimaging 615 0$aMedical physics. 615 0$aCancer$xImaging. 615 0$aNanochemistry. 615 0$aNanotechnology. 615 0$aBiophysics. 615 14$aMedical Physics. 615 24$aCancer Imaging. 615 24$aNanochemistry. 615 24$aNanoengineering. 615 24$aBioanalysis and Bioimaging. 676 $a616.99406 700 $aSavari$b Mohammad-Nabil$01453406 702 $aJabali?$b ?Ali? 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910768201003321 996 $aTheranostic Iron-Oxide Based Nanoplatforms in Oncology$93656018 997 $aUNINA