LEADER 03878nam  22005415  450 
001 9910767544903321
005 20251008140512.0
010   $a9783031196164$b(eBook)
010   $z9783031196157
024 7 $a10.1007/978-3-031-19616-4
035   $a(CKB)5580000000493710
035   $a(DE-He213)978-3-031-19616-4
035   $a(EXLCZ)995580000000493710
100   $a20221218d2023      u|         0
101 0 $aeng
135   $aurnn|008mamaa
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aMatrix Pathobiology and Angiogenesis /$fedited by Evangelia Papadimitriou, Constantinos M. Mikelis
205   $a1st ed. 2023.
210  1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2023.
215   $a1 online resource (XXVII, 320 p. 1 illus.) 
225 1 $aBiology of Extracellular Matrix,$x2191-1959 ;$v12
311 08$a3-031-19615-5 
327   $aChapter 1: Fibronectin Fibrillogenesis during Angiogenesis -- Chapter 2: Functional Interplay Between Fibronectin and Matricellular Proteins in the Control of Endothelial Tubulogenesis -- Chapter 3: Endothelial Cell-Matrix Interactions in Angiogenesis and Vessel Homeostasis: A Focus on Laminins and Their Integrin Receptors -- Chapter 4: Collagens and collagen-degrading enzymes in the regulation of angiogenesis -- Chapter 5: Kruppel-like factor 2 and matrix metalloproteinases in the context of vasculature -- Chapter 6: Extracellular Matrix-Remodeling Enzymes as Targets for Natural Antiangiogenic Compounds -- Chapter 7: Cell - extracellular matrix adhesions in vascular endothelium -- Chapter 8: Hypoxia: a potent regulator of angiogenesis through extracellular matrix remodeling -- Chapter 9: Leading roles of heparan sulfate in angiogenesis and cancer -- Chapter 10: The role of pericytes in tumor angiogenesis -- Chapter 11: Lymphatic Mechanoregulation in Development and Disease.
330   $aIn the vasculature, the extracellular matrix (ECM) is involved in the regulation of angiogenesis, vascular mechanosensing, and blood vessel stability. This book aims to provide the reader with an overview of the various roles of the ECM during angiogenesis and covers its important role for the maintenance of vascular integrity, capillary and arterial morphogenesis, as well as lymphangiogenesis. Furthermore, aspects of regulation of endothelial cell and pericyte functions by the ECM under physiological and pathological conditions are discussed. In addition, the reader will learn more about different approaches to exploit ECM molecules for designing therapeutic approaches or as biomarkers to improve therapeutic decisions. Comprehensive and cutting-edge, Matrix Pathobiology and Angiogenesis is a valuable resource for experienced researchers and early career scientist alike, who are interested in in learning more about this exciting and developing field. The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology and the International Society for Matrix Biology.
410  0$aBiology of Extracellular Matrix,$x2191-1959 ;$v12
606   $aBlood-vessels$xGrowth
606   $aCytology
606   $aClinical biochemistry
606   $aAngiogenesis
606   $aCell Biology
606   $aMedical Biochemistry
615  0$aBlood-vessels$xGrowth.
615  0$aCytology.
615  0$aClinical biochemistry.
615 14$aAngiogenesis.
615 24$aCell Biology.
615 24$aMedical Biochemistry.
676   $a571.8
676   $a573.18
702   $aPapadimitriou$b Evangelia$4edt$4http://id.loc.gov/vocabulary/relators/edt
702   $aMikelis$b Constantinos M$4edt$4http://id.loc.gov/vocabulary/relators/edt
906   $aBOOK
912   $a9910767544903321
996   $aMatrix Pathobiology and Angiogenesis$93655390
997   $aUNINA