LEADER 05564nam 22008415 450 001 9910767506003321 005 20251226200253.0 010 $a3-540-45768-2 024 7 $a10.1007/11875741 035 $a(CKB)1000000000283773 035 $a(SSID)ssj0000316800 035 $a(PQKBManifestationID)11274448 035 $a(PQKBTitleCode)TC0000316800 035 $a(PQKBWorkID)10276360 035 $a(PQKB)11196538 035 $a(DE-He213)978-3-540-45768-8 035 $a(MiAaPQ)EBC3068258 035 $a(PPN)123138663 035 $a(BIP)34164349 035 $a(BIP)13637548 035 $a(EXLCZ)991000000000283773 100 $a20100324d2006 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt 182 $cc 183 $acr 200 10$aComputational Life Sciences II $eSecond International Symposium, CompLife 2006, Cambridge, UK, September 27-29, 2006, Proceedings /$fedited by Michael R. Berthold, Robert Glen, Ingrid B. Fischer 205 $a1st ed. 2006. 210 1$aBerlin, Heidelberg :$cSpringer Berlin Heidelberg :$cImprint: Springer,$d2006. 215 $a1 online resource (XIII, 269 p.) 225 1 $aLecture Notes in Bioinformatics,$x2366-6331 ;$v4216 300 $aBibliographic Level Mode of Issuance: Monograph 311 08$a3-540-45767-4 320 $aIncludes bibliographical references and index. 327 $aGenomics -- Improved Robustness in Time Series Analysis of Gene Expression Data by Polynomial Model Based Clustering -- A Hybrid Grid and Its Application to Orthologous Groups Clustering -- Promoter Prediction Using Physico-Chemical Properties of DNA -- Parametric Spectral Analysis of Malaria Gene Expression Time Series Data -- An Efficient Algorithm for Finding Long Conserved Regions Between Genes -- The Reversal Median Problem, Common Intervals, and Mitochondrial Gene Orders -- Data Mining -- Building Structure-Property Predictive Models Using Data Assimilation -- Set-Oriented Dimension Reduction: Localizing Principal Component Analysis Via Hidden Markov Models -- Relational Subgroup Discovery for Descriptive Analysis of Microarray Data -- Applicability of Loop Recombination in Ciliates Using the Breakpoint Graph -- High-Throughput Identification of Chemistry in Life Science Texts -- Beating the Noise: New Statistical Methods for Detecting Signals in MALDI-TOF Spectra Below Noise Level -- Molecular Simulation -- Dynamic Complexity of Chaotic Transitions in High-Dimensional Classical Dynamics: Leu-Enkephalin Folding -- Solvent Effects and Conformational Stability of a Tripeptide -- Grid Assisted Ensemble Molecular Dynamics Simulations of HIV-1 Proteases Reveal Novel Conformations of the Inhibitor Saquinavir -- Molecular Informatics -- A Structure-Based Analysis of Single Molecule Force Spectroscopy (SMFS) Data for Bacteriorhodopsin and Four Mutants -- Classifying the World Anti-Doping Agency?s 2005 Prohibited List Using the Chemistry Development Kit Fingerprint -- A Point-Matching Based Algorithm for 3D Surface Alignment of Drug-Sized Molecules -- Systems Biology -- Adaptive Approach for Modelling Variability in Pharmacokinetics -- A New Approach to Flux Coupling Analysis of MetabolicNetworks -- Biological Networks / Metabolism -- Software Supported Modelling in Pharmacokinetics -- On the Interpretation of High Throughput MS Based Metabolomics Fingerprints with Random Forest -- Construction of Correlation Networks with Explicit Time-Slices Using Time-Lagged, Variable Interval Standard and Partial Correlation Coefficients -- Computational Neuroscience -- The Language of Cortical Dynamics -- A Simple Method to Simultaneously Track the Numbers of Expressed Channel Proteins in a Neuron. 330 $aThis book constitutes the refereed proceedings of the Second International Symposium on Computational Life Sciences, CompLife 2006. The 25 revised full papers presented were carefully reviewed and selected from 56 initial submissions. The papers are organized in topical sections on genomics, data mining, molecular simulation, molecular informatics, systems biology, biological networks/metabolism, and computational neuroscience. 410 0$aLecture Notes in Bioinformatics,$x2366-6331 ;$v4216 606 $aLife sciences 606 $aComputer science 606 $aInformation storage and retrieval systems 606 $aMedical informatics 606 $aDatabase management 606 $aApplication software 606 $aLife Sciences 606 $aTheory of Computation 606 $aInformation Storage and Retrieval 606 $aHealth Informatics 606 $aDatabase Management 606 $aComputer and Information Systems Applications 615 0$aLife sciences. 615 0$aComputer science. 615 0$aInformation storage and retrieval systems. 615 0$aMedical informatics. 615 0$aDatabase management. 615 0$aApplication software. 615 14$aLife Sciences. 615 24$aTheory of Computation. 615 24$aInformation Storage and Retrieval. 615 24$aHealth Informatics. 615 24$aDatabase Management. 615 24$aComputer and Information Systems Applications. 676 $a572.80285 701 $aBerthold$b M$g(Michael)$0133096 701 $aGlen$b Robert$g(Robert Charles)$01751732 701 $aFischer$b Ingrid$01751733 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910767506003321 996 $aComputational life sciences II$94186830 997 $aUNINA