LEADER 05032nam 22007575 450 001 9910766895503321 005 20251222143833.0 010 $a3-031-46026-X 024 7 $a10.1007/978-3-031-46026-5 035 $a(CKB)29092404700041 035 $a(MiAaPQ)EBC30977764 035 $a(Au-PeEL)EBL30977764 035 $a(DE-He213)978-3-031-46026-5 035 $a(EXLCZ)9929092404700041 100 $a20231128d2023 u| 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aAllergic to Life $eHow the Human Body Rejects the Modern World /$fby Frank Lichtenberger 205 $a1st ed. 2023. 210 1$aCham :$cSpringer Nature Switzerland :$cImprint: Springer,$d2023. 215 $a1 online resource (186 pages) 311 08$a9783031460258 320 $aIncludes bibliographical references and index. 327 $aPreface: Concerning humans -- Introduction: We?re not supposed to be here -- A Strange New World, Same Old Humans -- Mechanisms of Rejection -- House Dust Mites -- The Human Ecosystem -- Humans are What We Eat (Quantity v Quality) -- It?s About Time to Eat -- Indoor/Outdoor Air Quality -- Human Social Interactions -- The Human Brain Input/Output -- The Adjustment Mechanism of the Body: Mast Cell -- Desensitize from the World. 330 $aThis easy-to-read title provides a comprehensive discussion of the major changes in daily life that have led to states of increased bodily inflammation. Indeed, today there is an epidemic of allergic and autoimmune disease in the first and developing world. While outdoor climate change is now considered common knowledge, the impact of longer work hours, artificial lighting, increased food shelf life, and changes to the microbiome all have made a large impact in increasing allergies worldwide. An allergy, best defined as a ?damaging response from the Immune system due to a substance in the environment,? starts with warning signals, or generalized "symptoms," that are caused by something in the environment. Itching, aches, pains, swelling, coughing, and fatigue are all immune responses. Written in an engaging -- and often humorous -- style by an allergist/immunologist, the first three chapters outline how the humanbody is in an unquestionably harmful environment, and that, in general, the immune system is just doing its job. In subsequent chapters, the specific topics contributing to allergies are covered in detail, starting with microorganisms and a focus on indoor living. Dust mites, for example, are addressed in one full chapter -- and for good reason. The past few decades have seen an explosion of climate controlled, humidified indoor airspace that is ideally suited for more mass production of mites. In the end, emphasizes the author, all roads of inflammation from the environment lead to the ?mast cell compartment.? The stress responses of the body summarily drive up this compartment and have led to a world-wide prevalence of between 14% to 17% of ?mast cell activation syndrome.? While genetics and comorbid conditions are important in any symptom or disease process, the mast cell compartment feeds and grows off all the majorenvironmental changes of the past 50 or so years. This is why the human body in the 21st century is in a low level state of ?rejection,? of the world, says the author. Most of these changes are irreversible, but the situation is not hopeless. Understanding how the body changes itself in response to its environment will allow controlled desensitization to the environment. Allergic to Life: How the Human Body Rejects the Modern World serves as a concise and lively text for clinicians and general readers interested in a deep, expert dive into the world of allergy and immunology. . 606 $aAllergy 606 $aDermatology 606 $aFamily medicine 606 $aInternal medicine 606 $aPrimary care (Medicine) 606 $aNursing 606 $aAdulthood 606 $aAllergology 606 $aDermatology 606 $aGeneral Practice and Family Medicine 606 $aInternal Medicine 606 $aPrimary Care Medicine 606 $aAdult Nursing 606 $aAl·lèrgia$2thub 608 $aLlibres electrònics$2thub 615 0$aAllergy. 615 0$aDermatology. 615 0$aFamily medicine. 615 0$aInternal medicine. 615 0$aPrimary care (Medicine) 615 0$aNursing. 615 0$aAdulthood. 615 14$aAllergology. 615 24$aDermatology. 615 24$aGeneral Practice and Family Medicine. 615 24$aInternal Medicine. 615 24$aPrimary Care Medicine. 615 24$aAdult Nursing. 615 7$aAl·lèrgia 676 $a616.97 700 $aLichtenberger$b Frank$01450035 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910766895503321 996 $aAllergic to Life$93648880 997 $aUNINA