LEADER 05864nam 22006255 450 001 9910766882803321 005 20231127010957.0 010 $a981-19-9605-9 024 7 $a10.1007/978-981-19-9605-4 035 $a(MiAaPQ)EBC30974056 035 $a(Au-PeEL)EBL30974056 035 $a(DE-He213)978-981-19-9605-4 035 $a(CKB)29084008100041 035 $a(EXLCZ)9929084008100041 100 $a20231127d2023 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aNatural Product Based Drug Discovery Against Human Parasites $eOpportunities and Challenges /$fedited by Archana Singh, Brijesh Rathi, Anita K. Verma, Indrakant K. Singh 205 $a1st ed. 2023. 210 1$aSingapore :$cSpringer Nature Singapore :$cImprint: Springer,$d2023. 215 $a1 online resource (602 pages) 311 08$aPrint version: Singh, Archana Natural Product Based Drug Discovery Against Human Parasites Singapore : Springer Singapore Pte. Limited,c2024 327 $aChapter 1. Recent advances on the discovery of plants derived bioactive scaffolds/extracts against parasitic diseases -- Chapter 2. Applications of Computational Methods in Natural Products based Drug Discovery -- Chapter 3. Natural Product-Based Drug Designing for treatment of Human parasitic diseases -- Chapter 4. Secondary Metabolites of Plant Origin in Parasitic manifestations -- Chapter 5. Exploring marine biodiversity as alternative resources for treatment of Human Parasitic Diseases -- Chapter 6. Marine Bioprospecting for the Treatment of Human Parasitic Diseases -- Chapter 7. Microorganisms-Derived Biochemicals: Potential Drugs for Human Parasitic Diseases -- Chapter 8. Plant-Based Vaccines against Human Parasitic Diseases -- Chapter 9. Nanotechnology: its usages in drug delivery for the treatment of Human Parasitic Diseases -- Chapter 10. Therapeutic Potential Of Benzopyrones Against Antiparasitic Diseases -- Chapter 11. Antimicrobial peptides (AMPs): current state and future prospects for the treatment of human parasitic diseases -- Chapter 12. Pathway To Register Natural Product-Derived Therapeutics -- Chapter 13. Recent Advances in the Treatment of Parasitic Diseases: Current Status and Future -- Chapter 14. Strategies and challenges for developing plant-based therapeutics against Protozoans -- Chapter 15. Recent approaches to combat toxoplasma gondii with plant-derived alternatives -- Chapter 16. Target-based rational improvement strategies and pitfalls in Leishmania drug discovery -- Chapter 17. Versatile Structurally Diverse Natural Products and Their Semisynthetic Analogs as Potential Anti-leishmanial Drugs -- Chapter 18. Promising compounds of plant origin and their synthetic analogs against Trypanosomes -- Chapter 19. Pathogenesis and Immune Response inT. cruzi infection: Quest for Natural compound-based drugs -- Chapter 20. Limitations of current drugs and prospects of plant-based compounds and their constructed analogues as therapeutics for treatment of malaria -- Chapter 21. An Analytical Approach to Progression in Malaria Therapeutics -- Chapter 22. Malaria Drug Discovery: How to tackle the problem of Drug Resistance -- Chapter 23. Approaches to drug discovery against Ascariasis: Opportunity and challenges in plant-based products -- Chapter 24. The Potential of Plant Secondary Metabolites as Drugs or Leads Against Helminths -- Chapter 25. Drug Resistance in Helminth parasites: Role of plant based natural therapeutics -- Chapter 26. Schistosomiasis: current and future strategies to develop novel therapeutics. 330 $aThis book comprehensively reviews current and novel treatment strategies against human parasites, including protozoans and helminths, using natural products. The initial chapters summarize the conventional treatment strategies and natural-product based therapeutics against these parasites. It discusses biochemical tools and techniques for the discovery of natural product based drugs against human parasites. The book also covers the ingenious and innovative mechanisms to achieve drug resistance by the protozoan parasites and strategies to overcome the resistance. It entails mechanistic insight into the modulation of host immune responses to delay or inhibit parasite clearance and explores host-pathogen interactions that mediate immunity against subsequent parasite challenge. In turn, the volume helps in understanding the immunobiology of the parasites and tools to identify candidate vaccine antigens and novel delivery systems against the protozoan parasites. Lastly, it explores the role of advanced methods, including nanotechnology, marine bioprospecting, and microorganisms-derived biochemicals against the protozoan parasites. This book is useful for students and researchers of pharmacology, parasitology, zoology and other allied fields. 606 $aParasitology 606 $aMedical microbiology 606 $aPharmacology 606 $aDrugs$xDesign 606 $aParasitology 606 $aMedical Microbiology 606 $aPharmacology 606 $aStructure-Based Drug Design 615 0$aParasitology. 615 0$aMedical microbiology. 615 0$aPharmacology. 615 0$aDrugs$xDesign. 615 14$aParasitology. 615 24$aMedical Microbiology. 615 24$aPharmacology. 615 24$aStructure-Based Drug Design. 676 $a616.96 700 $aSingh$b Archana$0972620 701 $aRathi$b Brijesh$01450618 701 $aVerma$b Anita K$01450619 701 $aSingh$b Indrakant K$01450620 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910766882803321 996 $aNatural Product Based Drug Discovery Against Human Parasites$93650099 997 $aUNINA