LEADER 02575nam 2200361 450 001 9910765892203321 005 20230219094513.0 010 $a3-03842-607-5 035 $a(CKB)5400000000000468 035 $a(NjHacI)995400000000000468 035 $a(EXLCZ)995400000000000468 100 $a20230219d2017 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aLC-MS/MS method for mycotoxin analysis /$fedited by Aldo Lagana? 210 1$aBasel, Switzerland :$cMDPI,$d[2017] 210 4$dİ2017 215 $a1 online resource (194 pages) $cillustrations 320 $aIncludes bibliographical references. 330 $aMycotoxins are secondary metabolites produced by some species of filamentous fungi belonging to Fusarium, Aspergillus, Penicillium, Claviceps and Alternaria genera. The biochemical significance of mycotoxins in fungal metabolism has not always been fully clarified; however, the main concern for mycotoxins is driven by the deleterious effects they can exert on human and animal health. Structurally, the mycotoxins currently known belong to heterogeneous chemical classes, therefore the toxic effects they can induce are highly diverse (e.g., cancerogenic and immunosuppressive effects). The main route of human exposure to mycotoxins is by intake of contaminated food, either directly from contaminated agricultural products, or indirectly from residues and metabolites present in foods of animal origin. Immunochemical methods are generally used for the fast screening of mycotoxin presence; however, for confirmation purposes, analytical methods based on high-performance liquid chromatography (LC) are preferred, especially when coupled with tandem mass spectrometry (MS/MS), which allows the determination of multiclass mycotoxins in a single analysis. Moreover, the technical innovations available in LC-MS/MS instrumentation are prompting its application to the monitoring of contaminants in food and feed. The aim of this paper collection, constituted by ten research articles and one review, is to provide the reader with an overview on the novelties and capabilities in LC-MS/MS-based multi-mycotoxin methods, also including the investigation of emerging and modified mycotoxins. 606 $aMycotoxins 615 0$aMycotoxins. 676 $a615.95295 702 $aLagana?$b Aldo 801 0$bNjHacI 801 1$bNjHacl 906 $aBOOK 912 $a9910765892203321 996 $aLC-MS$92936244 997 $aUNINA