LEADER 00977nam 2200337 450 001 9910765513503321 005 20231211121749.0 010 $a9978-10-817-3 035 $a(CKB)5860000000447910 035 $a(NjHacI)995860000000447910 035 $a(EXLCZ)995860000000447910 100 $a20231211d2022 uy 0 101 0 $apor 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aCambio clima?tico $eAcuerdos y contradicciones /$fTania Chicaiza Villalba 210 1$a[Place of publication not identified] :$cEditorial Abya-Yala,$d2022. 215 $a1 online resource 311 $a9978-10-762-2 606 $aClimate change 615 0$aClimate change. 676 $a363.73874 700 $aChicaiza Villalba$b Tania$01450227 801 0$bNjHacI 801 1$bNjHacl 906 $aBOOK 912 $a9910765513503321 996 $aCambio clima?tico$93649302 997 $aUNINA LEADER 02067nam 2200469z- 450 001 9910345962003321 005 20210211 035 $a(CKB)4920000000094094 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/42011 035 $a(oapen)doab42011 035 $a(EXLCZ)994920000000094094 100 $a20202102d2019 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aBeyond Borders: Myotonic Dystrophies - A European Perception 210 $cFrontiers Media SA$d2019 215 $a1 online resource (148 p.) 225 1 $aFrontiers Research Topics 311 08$a2-88945-709-5 330 $aMyotonic dystrophies (DMs) are pleotropic multisystemic diseases. These dominantly transmitted repeat disorders affect multiple organs of the human body at all ages - from the newborns to the elderly. The present Research Topic represents a timely addition to the expanding body of evidence which aims to provide novel perspectives in our understanding of myotonic dystrophies. This collection of original contributions and standpoint reviews from multiple leading DM centres in Europe describes the state of the art for the characterization of the DMs diseases, the development of molecular strategies to target its multisystemic nature, and provides evidence of screening and testing novel therapeutic avenues. 517 $aBeyond Borders 606 $aMedicine$2bicssc 610 $aanimal models 610 $abrain imaging 610 $acell models 610 $aCNS involvement 610 $aDM1 610 $aDM2 610 $amultisystemic diseases 610 $amyotonic dystrophy type 1 and type 2 610 $aphenotypes 610 $arepeat disorders 615 7$aMedicine 700 $aSchoser$b Benedikt$4auth$01767366 702 $aMeola$b Giovanni 906 $aBOOK 912 $a9910345962003321 996 $aBeyond Borders: Myotonic Dystrophies - A European Perception$94212515 997 $aUNINA