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010   $a3-031-35811-2
024 7 $a10.1007/978-3-031-35811-1
035   $a(MiAaPQ)EBC30881075
035   $a(Au-PeEL)EBL30881075
035   $a(DE-He213)978-3-031-35811-1
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100   $a20231110d2023      u|         0
101 0 $aeng
135   $aurcnu||||||||
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aPharmaceutical Formulations for Older Patients /$fedited by Mine Orlu, Fang Liu
205   $a1st ed. 2023.
210  1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2023.
215   $a1 online resource (294 pages)
225 1 $aAAPS Advances in the Pharmaceutical Sciences Series,$x2210-738X ;$v51
311 08$aPrint version: Orlu, Mine Pharmaceutical Formulations for Older Patients Cham : Springer International Publishing AG,c2023 9783031358104 
327   $aPart 1: Patient-Centric Considerations.-Medicine Optimisation in Older  -- Acceptability of drug formulations in older patients and effect on patient adherence -- Geriatric biopharmaceutics -- Excipient safety in older adults -- Part 2: Pharmaceutical Formulations Development for older Patients -- Oral and oromucosal formulation development and in vitro characterisation ? patient-centric approaches for older adults -- Pulmonary drug delivery systems for older people -- Transdermal drug delivery systems for older patients -- Part 3 :Advanced Drug Delivery Systems for Older Patients -- Advanced oral drug delivery systems for older patients -- The ageing microbiome, pharmaceutical considerations and therapeutic opportunities -- Application of 3D printing in geriatric medicines, -- Application of electrospraying and advanced fabrication methods in geriatric medicines -- Vaccine development for older patients.
330   $aPharmaceutical formulation design affects patient acceptability/adherence and pharmacokinetics of the drug. This is particularly important for older patients because of the physiological changes due to ageing and clinical/social circumstances related to medicine taking. This book provides a comprehensive review in the design of formulations to meet the needs of older patients. An overview of the key clinical, social and pharmaceutical factors affecting medication optimization, safety and acceptability in older adults is included, followed by patient-centric considerations including regulatory requirements, dosage form design and human factor studies. Advanced pharmaceutical technologies are discussed for their potential use in older adults such as 3D printing, long-acting oral formulations and novel vaccine technologies. The unique focus of the book will be of interest to pharmaceutical scientists in both industry and academia in searching for better formulations for older patients.
410  0$aAAPS Advances in the Pharmaceutical Sciences Series,$x2210-738X ;$v51
606   $aDrug delivery systems
606   $aPharmaceutical chemistry
606   $aPharmacology
606   $aMedicine$xResearch
606   $aBiology$xResearch
606   $aDrug Delivery
606   $aPharmaceutics
606   $aPharmacology
606   $aBiomedical Research
615  0$aDrug delivery systems.
615  0$aPharmaceutical chemistry.
615  0$aPharmacology.
615  0$aMedicine$xResearch.
615  0$aBiology$xResearch.
615 14$aDrug Delivery.
615 24$aPharmaceutics.
615 24$aPharmacology.
615 24$aBiomedical Research.
676   $a615.70846
700   $aOrlu$b Mine$01439068
701   $aLiu$b Fang$0674440
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910763595403321
996   $aPharmaceutical Formulations for Older Patients$93601295
997   $aUNINA