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101 0 $aeng
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181   $ctxt$2rdacontent
182   $cc$2rdamedia
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200 10$aPrecision Medicine /$fedited by Ingolf Cascorbi, Matthias Schwab
205   $a1st ed. 2023.
210  1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2023.
215   $a1 online resource (285 pages)
225 1 $aHandbook of Experimental Pharmacology,$x1865-0325 ;$v280
311 08$aPrint version: Cascorbi, Ingolf Precision Medicine Cham : Springer International Publishing AG,c2023 9783031400469 
327   $aPart 1. Pharmacogenomics -- Building evidence in RCTs Implementation of pharmacogenomics in healthcare in the UK -- Part 2. Precision medicine in clinical entities -- Precision medicine in therapy of non-solid cancer -- Molecular Mechanisms of Tyrosine Kinase Inhibitor Resistance in Chronic Myeloid Leukemia -- Precision medicine in Asthma -- Precision medicine in Diabetes -- Precision Medicine in Antidepressants Treatment -- Precision Medicine in Neuropathic Pain -- Part 3. Techniques in Precision Medicine -- Imaging techniques in pharmacological precision medicine -- Challenges to use NGS data to optimize drug therapy -- Part 4. Economics -- Pharmacoeconomics in precision medicine. .
330   $aThe rapidly increased understanding of the molecular background of complex diseases facilitated the development of highly advanced therapeutic concepts. Such concepts aiming to consider individual signatures of genomic and proteomic biomarkers including pharmacogenomics as well as advanced diagnostic tools have been successfully implemented in clinical practice in various fields leading to significant improvement of treatment successes. This volume gives an up-to-date overview on applications of precision medicine in various clinical entities, on advanced techniques as well as on economic considerations.
410  0$aHandbook of Experimental Pharmacology,$x1865-0325 ;$v280
606   $aPharmacology
606   $aInternal medicine
606   $aCancer
606   $aPharmacology
606   $aInternal Medicine
606   $aCancer Biology
615  0$aPharmacology.
615  0$aInternal medicine.
615  0$aCancer.
615 14$aPharmacology.
615 24$aInternal Medicine.
615 24$aCancer Biology.
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700   $aCascorbi$b Ingolf$01426803
701   $aSchwab$b Matthias$01426804
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