LEADER 04082nam 22006135 450 001 9910743687303321 005 20230901081830.0 010 $a3-031-37981-0 024 7 $a10.1007/978-3-031-37981-9 035 $a(MiAaPQ)EBC30727055 035 $a(Au-PeEL)EBL30727055 035 $a(DE-He213)978-3-031-37981-9 035 $a(PPN)272736090 035 $a(CKB)28141334000041 035 $a(EXLCZ)9928141334000041 100 $a20230901d2023 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aPhysical Principles of Electro-Mechano-Biology $eMultiphysics and Supramolecular Approaches /$fby Christian Brosseau 205 $a1st ed. 2023. 210 1$aCham :$cSpringer Nature Switzerland :$cImprint: Springer,$d2023. 215 $a1 online resource (304 pages) 225 1 $aStudies in Mechanobiology, Tissue Engineering and Biomaterials,$x1868-2014 ;$v25 311 08$aPrint version: Brosseau, Christian Physical Principles of Electro-Mechano-Biology Cham : Springer International Publishing AG,c2023 9783031379802 320 $aIncludes bibliographical references and index. 327 $aPart 1. Background -- Chapter 1. Elementary concepts and definitions -- Chapter 2. A Brief Sketch of the History of EMB: Where Good Ideas Come From -- Part 2. Calculation Methods -- Chapter 3. Supramolecular Analytical Approaches of EMB -- Chapter 4. Computational approaches of EMB -- Generic Final Remarks -- Challenges Ahead. 330 $aThis book covers the recently developed understanding of Electro-Mechano-Biology (EMB) in which the focus is primarily on the couplings between the electric and mechanical fields. The emphasis lies on the analytical and computational aspects of EMB at the cellular level. The book is divided into two parts. In the first part, the author starts by defining and discussing the relevant basic aspects of the electrical and mechanical properties of cell membranes. He provides an overview of some of the ways analytical modelling of cell membrane electrodeformation (ED) and electroporation (EP) appears in a variety of contexts as well as a contemporary account of recent developments in computational approaches that can feature in the theory initiative, particularly in its attempt to describe the cohort of activities currently underway. Intended to serve as an introductory text and aiming to facilitate the understanding of the field to non-experts, this part does not dwell on the set of topics, such as cellular mechanosensing and mechanotransduction, irreversible EP, and atomistic molecular dynamics modelling of membrane EP. The second (and larger) part of the book is devoted to a presentation of the necessary analytical and computational tools to illustrate the ideas behind EMB and illuminate physical insights. Brief notes on the history of EMB and its many applications describing the variety of ideas and approaches are also included. In this part, the background of the first principles and practical calculation methods are discussed to highlight aspects that cannot be found in a single volume. 410 0$aStudies in Mechanobiology, Tissue Engineering and Biomaterials,$x1868-2014 ;$v25 606 $aBiophysics 606 $aCell interaction 606 $aMathematical physics 606 $aComputer simulation 606 $aBiophysics 606 $aMechanobiological Cell Signaling 606 $aComputational Physics and Simulations 615 0$aBiophysics. 615 0$aCell interaction. 615 0$aMathematical physics. 615 0$aComputer simulation. 615 14$aBiophysics. 615 24$aMechanobiological Cell Signaling. 615 24$aComputational Physics and Simulations. 676 $a612.01427 700 $aBrosseau$b Christian$f1959-$01427255 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910743687303321 996 $aPhysical principles of electro-mechano-biology$93560167 997 $aUNINA