LEADER 01431nam0 22003251i 450 001 SUN0014336 005 20061105120000.0 010 $a88-15-03228-2 020 $aIT$b92 8493 100 $a20031204d1991 |0itac50 ba 101 $aita 102 $aIT 105 $a|||| ||||| 200 1 $aMetodi della ricerca sociale$fKenneth D. Bailey 205 $a[2. ed.] 210 $aBologna$cIl mulino$d[1991] 215 $a566 p.$cill.$d25 cm. - Ed. italiana a cura di Maurizio Rossi. - Segue: Appendice. 410 1$1001SUN0005273$12001 $aStrumenti. Scienze sociali$1210 $aBologna$cIl mulino. 620 $dBologna$3SUNL000003 676 $a301.07$v21 700 1$aBailey$b, Kenneth D.$3SUNV010447$090373 712 $aIl mulino$3SUNV000011$4650 801 $aIT$bSOL$c20181109$gRICA 912 $aSUN0014336 950 $aUFFICIO DI BIBLIOTECA DEL DIPARTIMENTO DI GIURISPRUDENZA$d00 CONS XXI.Cc.13 $e00 3127 950 $aUFFICIO DI BIBLIOTECA DEL DIPARTIMENTO DI PSICOLOGIA$d16 CONS 141 $e16 VS 1822 995 $aUFFICIO DI BIBLIOTECA DEL DIPARTIMENTO DI GIURISPRUDENZA$h3127$kCONS XXI.Cc.13$op$qa 995 $aUFFICIO DI BIBLIOTECA DEL DIPARTIMENTO DI PSICOLOGIA$bIT-CE0119$gVS$h1822$kCONS 141$oc$qa 996 $aMethods of social research$914715 997 $aUNICAMPANIA LEADER 05671nam 2201465z- 450 001 9910743282503321 005 20230911 035 $a(CKB)5690000000228482 035 $a(oapen)doab113977 035 $a(EXLCZ)995690000000228482 100 $a20230920c2023uuuu -u- - 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aIonizing Radiation, Antioxidant Response and Oxidative Damage: Radiomodulators 210 $cMDPI - Multidisciplinary Digital Publishing Institute$d2023 215 $a1 online resource (322 p.) 311 08$a3-0365-8189-8 330 $aIonizing radiation (IR) exposure can be deleterious for living tissues and eventually lead to illness or even death. DNA breakdown and the overproduction of highly reactive free radicals, reactive oxygen species (ROS) and reactive nitrogen species (RNS) are considered initiators of IR-induced molecular and cellular damages, whereas NO, TGF-? and other pro-inflammatory cytokines are the primary effectors involved in radiation bystander effects (RIBE). Radiomodulators can reduce (radioprotectors and radiomitigators) or increase (radiosensitizers) IR damage. Past world events have highlighted the urgent need to develop predictive biomarkers of the IR absorbed dose and radiation countermeasures to reduce IR damage. Despite the strong economic and scientific efforts over the last decades, at present, drugs for effective protection against lethal IRs remain an unmet need. Moreover, the development of radiosensitizers that selectively increase IR damage in cancer cells but protecting, or at least do not affect, healthy tissues is also of unquestionable importance to improving patient survival and quality of life. It includes contributions that will help to understand the mechanisms involved in radiation-derived cellular responses and damage, the importance of free radical scavengers and antioxidant cellular defenses in preventing harm, and the relevance of the antiinflammatory response to improve recovery. In accordance, the mechanism of action and effectiveness of relevant radiomodulators are described and discussed, and novel clinical models and IR biomarker technologies are presented. 517 $aIonizing Radiation, Antioxidant Response and Oxidative Damage 606 $aMedicine and Nursing$2bicssc 606 $aPharmacology$2bicssc 610 $a3T3 fibroblasts 610 $aacute gamma irradiation 610 $aamino acid sequences 610 $aantioxidant 610 $aantioxidant defense system 610 $aapoptosis 610 $aATP 610 $aAuranofin 610 $abacterial dietary supplement 610 $abioinformatics 610 $abone marrow injury 610 $abone marrow microenvironment 610 $aC57Bl/6 mice 610 $acancer 610 $acellular stress 610 $acombination therapy 610 $adysbiosis 610 $aelectron beam radiation 610 $aelectron paramagnetic resonance (EPR) 610 $aferulic acid 610 $aFT-IR 610 $agene signature 610 $aGSH 610 $aH2O2 610 $ahuman lactoferrin 610 $ahyperthermia 610 $ahypoxia 610 $aimmune response 610 $aintestine 610 $aionising radiation 610 $aionizing radiation 610 $airradiation 610 $aleukocytes 610 $aMDA 610 $amelatonin 610 $amicrobiome 610 $amicrobiota 610 $amitigation 610 $amodel animal 610 $amtDNA-mutations 610 $amucositis 610 $an/a 610 $anDNA-repair 610 $anormal tissue 610 $anuclear and radiological emergencies 610 $aOlea europaea L. cv. Caiazzana 610 $aoleacein 610 $aoncometabolites 610 $aopen field test 610 $aoxidation stress 610 $aoxidative modification profiling 610 $aoxidative phosphorylation 610 $aoxidative stress 610 $aoxygenation 610 $apancreatic cancer 610 $aperoxiredoxin 610 $aperoxiredoxin 6 610 $apharmacologic ascorbate 610 $aplanarians 610 $aPrdx6 610 $aproliferation 610 $aprotection 610 $aproteomic analysis 610 $aradiation 610 $aradiation biodosimetry 610 $aradiation biomarker 610 $aradiation response 610 $aradiobiology database 610 $aradiomitigator 610 $aradiomitigators 610 $aradiomodulation 610 $aradionuclide scavengers 610 $aradioprotection 610 $aradioprotector 610 $aradioprotectors 610 $aradioresistance 610 $aradiosensitization 610 $aradiotherapy 610 $areactive oxygen species 610 $aregeneration 610 $asenescence 610 $aserum albumin 610 $aserum homeostasis 610 $aspleen 610 $astem cell senescence 610 $astilbenoid 610 $asurvival rate 610 $asynergistic effect 610 $aTameron 610 $athioredoxin 610 $athioredoxin reductase 610 $atotal body irradiation 610 $atranscriptomics 610 $avitamin C 610 $aX-ray radiation 615 7$aMedicine and Nursing 615 7$aPharmacology 906 $aBOOK 912 $a9910743282503321 996 $aIonizing Radiation, Antioxidant Response and Oxidative Damage: Radiomodulators$93560343 997 $aUNINA