LEADER 04342nam 2200973z- 450 001 9910743279003321 005 20230911 035 $a(CKB)5690000000228517 035 $a(oapen)doab113916 035 $a(EXLCZ)995690000000228517 100 $a20230920c2023uuuu -u- - 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aNatural Products Chemistry: Advances in Synthetic, Analytical and Bioactivity Studies 210 $cMDPI - Multidisciplinary Digital Publishing Institute$d2023 215 $a1 online resource (228 p.) 311 08$a3-0365-8485-4 330 $aThe chemistry of natural products is rich in diversity, which can be noted from several perspectives. Plants, fungi, and marine organisms represent sources of small molecules characterized by unique complexity related to their varied scaffolds, functional groups, and stereochemistry. At the same time, extraction, de novo synthesis, derivatization, and semi-synthetic approaches represent challenging tasks for organic chemists. In parallel, analytical profiling of the content of organic compounds and microelements in natural matrices pushes experimental techniques to the edge of their potential due to the complex tasks involved in sample preparation and data elaboration. Additionally, flavonoids, alkaloids, and terpenes, as well as their semisynthetic derivatives, attract the interest of medicinal chemists due to their beneficial biological effects, which include antioxidant, antiproliferative, antibacterial, and anti-inflammatory activities. This Special Issue aimed to collect original contributions to describe the extraction, structural elucidation, and synthesis of natural, semisynthetic, and nature-inspired synthetic molecules. Moreover, articles that discuss the analysis of the content and bioactivity of natural compounds in complex matrices, as well as review articles that focus on the chemistry of natural products, were considered in combination with research articles that describe significant results in terms of their innovative synthetic and extractive, as well as advanced analytical, techniques (chromatography, 1D and 2D NMR, mass spectrometry, IR and UV spectroscopy, etc.). 517 $aNatural Products Chemistry 606 $aChemistry$2bicssc 606 $aResearch & information: general$2bicssc 610 $a1,2,3-triazole 610 $a5-HT 610 $aanti-metastasis 610 $aantibacterial 610 $aanticancer activity 610 $aapoptosis 610 $aArthrinium sp. 610 $aAspergillus 610 $abioactivity 610 $abiocatalysis 610 $achemoenzymatic 610 $achrysin 610 $acurcumin 610 $acurcuminoids 610 $acyclophosphamide 610 $acytotoxicity 610 $aD-IBS 610 $adeuterium labeling 610 $adocosahexaenoic acids 610 $aendophytic fungus 610 $aexpression analysis 610 $aflavones 610 $aGI dysfunction 610 $agranulosa cells 610 $agut microbiota 610 $ahybrids 610 $akaempferol 610 $alarvae of Musca domestica 610 $aliquid-chromatography tandem mass spectrometry 610 $aloonamycin 610 $amacamide 610 $amarine fungi 610 $ameasurement of vitamin D metabolites in blood 610 $amedicinal chemistry 610 $amolecular cloning 610 $an/a 610 $anatural compounds 610 $anatural product synthesis 610 $aO-glycan 610 $aovarian cancer 610 $aovary 610 $ap53 610 $aphenolics 610 $aPI3K/AKT/mTOR 610 $aprotocatechuic 610 $apyridone alkaloids 610 $aquinones 610 $asemi-synthetic compounds 610 $asesquiterpenoids 610 $astilbenes 610 $aTbUGGT 610 $aTrapa bispinosa Roxb. 610 $atriple negative breast cancer 610 $avitamin D 615 7$aChemistry 615 7$aResearch & information: general 906 $aBOOK 912 $a9910743279003321 996 $aNatural Products Chemistry: Advances in Synthetic, Analytical and Bioactivity Studies$93560308 997 $aUNINA