LEADER 03014nam 2200901z- 450 001 9910743274103321 005 20230911 035 $a(CKB)5690000000228567 035 $a(oapen)doab113881 035 $a(EXLCZ)995690000000228567 100 $a20230920c2023uuuu -u- - 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aChronic Kidney Disease: Underlying Molecular Mechanisms 210 $cMDPI - Multidisciplinary Digital Publishing Institute$d2023 215 $a1 online resource (216 p.) 311 08$a3-0365-8540-0 330 $aChronic kidney disease (CKD) is a worldwide public health problem that must be addressed. The global increase in CKD prevalence is associated with an increase in conventional disease risk factors (e.g., diabetes and hypertension), which may be exacerbated by additional variables such as environmental and occupational exposure to toxic compounds. Authors contributed to this Special Issue by highlighting the finding of potential novel biomarkers of the disease and more effective therapy alternatives, as well as works that enhance the understanding of CKD pathogenesis and its related complications. 517 $aChronic Kidney Disease 606 $aMedicine and Nursing$2bicssc 606 $aPharmacology$2bicssc 610 $aadipose tissue browning 610 $aarsenic 610 $abiomarkers 610 $acachexia 610 $acadmium 610 $acellular injury 610 $achildren 610 $achronic kidney disease 610 $aCKD 610 $adevelopmental origins of health and disease (DOHaD) 610 $aend-stage renal disease (ESRD) 610 $aexercise 610 $afibrosis 610 $aFSGS 610 $agrowth hormone 610 $agut microbiota 610 $aheavy metals 610 $ahypertension 610 $ainflammation 610 $akidney 610 $alipolysis 610 $alymphatics 610 $aMarinobufagenin (MBG) 610 $amass spectrometry 610 $aMCD 610 $amercury 610 $amuscle function 610 $amuscle mass 610 $an/a 610 $anervous and immune systems 610 $aNKCC1 transporter 610 $aNZO mice 610 $aoxidative stress 610 $apodocyte dysfunction 610 $aprebiotics 610 $aprobiotics 610 $areactive oxygen species (ROS) 610 $aSH045 610 $ashort-chain fatty acids 610 $askeletal muscle wasting 610 $asodium 610 $aTNF-alpha 610 $aTNFR 610 $atrimethylamine-N-oxide 610 $aTRPC6 610 $auremic toxins 610 $aurine proteome 610 $aUUO 615 7$aMedicine and Nursing 615 7$aPharmacology 906 $aBOOK 912 $a9910743274103321 996 $aChronic Kidney Disease: Underlying Molecular Mechanisms$93560539 997 $aUNINA