LEADER 04360nam 2200565Ia 450 001 9910741173803321 005 20200520144314.0 010 $a3-319-00389-5 024 7 $a10.1007/978-3-319-00389-4 035 $a(CKB)2670000000389000 035 $a(EBL)1317590 035 $a(SSID)ssj0000921456 035 $a(PQKBManifestationID)11539138 035 $a(PQKBTitleCode)TC0000921456 035 $a(PQKBWorkID)10960269 035 $a(PQKB)11666190 035 $a(DE-He213)978-3-319-00389-4 035 $a(MiAaPQ)EBC1317590 035 $a(PPN)170489728 035 $a(EXLCZ)992670000000389000 100 $a20111102d2013 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aDepression and drugs $ethe neurobehavioral structure of a psychological storm /$fMartin M. Katz 205 $a1st ed. 2013. 210 $aCham $cSpringer$d2013 215 $a1 online resource (101 p.) 225 0 $aSpringerBriefs in psychology 300 $aDescription based upon print version of record. 311 $a3-319-00388-7 320 $aIncludes bibliographical references and index. 327 $aIntroduction -- Uncovering the Interaction of Chemistry and Behavior in Depression: Dimensions vs. Diagnosis in Structuring Research -- Depression is a ?Storm? not a Lowering of Spirit: The Experience of the Severe Depressed State -- ?Rashomon? and the Componential Approach to Developing Measures of Mood and Behavior -- Dimensions of Depression: The Conflictual Structure of the Depressed State -- False Assumptions: The Multidimensional Quality and its Relationships to Functioning of the Central Nervous System -- Testing New Hypotheses about Neurochemistry, Depression and Drugs -- Developing a More Effective and More Efficient Clinical Trial Model -- Elaboration of the New Theory of Depression and Conclusions -- Postscript -- Appendix 1 The Multivantaged (MV) Assessment Methods -- Appendix 2 The Video Interview Behavior Evaluation Scales (VIBES). 330 $aIn the 1950s, psychiatric "miracle drugs" revolutionized the treatment of depression, improving the quality of life of countless patients. Over half a century and millions of prescriptions later, advances in brain structure, neurochemistry, and genetics are providing clues to the mechanisms of depression and pointing to new therapeutic possibilities.  Depression and Drugs makes the most of these recent developments, introducing both a neurobehavioral theory of chemical/behavioral interactions and a practical framework for modernizing the conceptualization, assessment, and treatment of depression. Its multidimensional analysis offers insights into the brain structures most affected by the disorder, and the complex phenomena involved in medication. By focusing on cognitive, behavioral, and mood effects as well as brain chemistry, the author identifies false leads that have led to impasses in developing better antidepressants and explains why "mild" cases are often the hardest to treat. These groundbreaking ideas bring readers their closest to scientifically answering the eternal questions How do depressive states form? and How do drugs resolve them? Included in the coverage:   Dimensions versus diagnosis in depression research. The experience of the severe depressed state. The componential approach to developing measures of mood and behavior. Testing new hypotheses about chemistry, depression, and drugs. Developing a more effective clinical trial model. Plus appendices detailing emerging assessment methods. This knowledge has the potential for sparking change across a number of fields, making Depression and Drugs of immediate interest to graduate students in psychology and medicine, practicing clinical psychologists, psychiatrists, clinical psychopharmacologists, and basic researchers in psychology and neuropsychopharmacology. 410 0$aSpringerBriefs in Psychology,$x2192-8363 606 $aNeuropsychology 606 $aDepression, Mental 615 0$aNeuropsychology. 615 0$aDepression, Mental. 676 $a616.8527061 700 $aKatz$b Martin M$0772578 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910741173803321 996 $aDepression and Drugs$93554344 997 $aUNINA