LEADER 03808nam 22006255 450 001 9910739487003321 005 20200705003257.0 010 $a1-4614-7351-9 024 7 $a10.1007/978-1-4614-7351-0 035 $a(CKB)3710000000024276 035 $a(EBL)1538540 035 $a(SSID)ssj0001049048 035 $a(PQKBManifestationID)11550205 035 $a(PQKBTitleCode)TC0001049048 035 $a(PQKBWorkID)11018905 035 $a(PQKB)10355376 035 $a(DE-He213)978-1-4614-7351-0 035 $a(MiAaPQ)EBC1538540 035 $a(PPN)176097988 035 $a(EXLCZ)993710000000024276 100 $a20131011d2013 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aSmoking and Lung Inflammation$b[electronic resource] $eBasic, Pre-Clinical and Clinical Research Advances /$fedited by Thomas J. Rogers, Gerard J. Criner, William D. Cornwell 205 $a1st ed. 2013. 210 1$aNew York, NY :$cSpringer New York :$cImprint: Springer,$d2013. 215 $a1 online resource (217 p.) 300 $aDescription based upon print version of record. 311 $a1-4614-7350-0 320 $aIncludes bibliographical references. 327 $aIntroduction -- Immunopathology of COPD -- Monocyte Populations Which Participate in Chronic Lung Inflammation -- Neutrophils Inflammation in COPD -- Role of Epithelial Cells in Chronic Inflammatory Lung Disease -- The Relationship Between Oxidative Stress Responses and Lung Inflammation with Cigarette Smoking -- Autoimmune Mechanisms Contributing to Chronic Obstructive Pulmonary Disease -- Chronic Obstructive Pulmonary Disease (COPD): Local and Systemic Disease -- Infectious Mechanisms Regulating Susceptibility to Acute Exacerbations of COPD -- COPD: Biomarkers and Phenotypes -- Anti-inflammatory Therapeutics in COPD: Past, Present and Future. 330 $aSmoking and Lung Inflammation is the first book directly related to chronic lung inflammation of its kind in several respects. First, the it focuses on both basic and clinical research on COPD, and the inflammatory mechanisms that function in these diseases. Second, it is unique with respect to scope of the discussion of the unusual characteristics of the immune response which occurs in these patients. Third, it includes knowledge being gained from translational research conducted through clinical trials at several Medical Schools in the United States. Not only is this research providing information about novel drugs and therapies, but it is also advancing our understanding of the genetics of these diseases. This work will illuminate the molecular basis for these diseases, and hopefully will permit us to individualize the therapies for these diseases. 606 $aImmunology 606 $aRespiratory organs?Diseases 606 $aPathology 606 $aImmunology$3https://scigraph.springernature.com/ontologies/product-market-codes/B14000 606 $aPneumology/Respiratory System$3https://scigraph.springernature.com/ontologies/product-market-codes/H33134 606 $aPathology$3https://scigraph.springernature.com/ontologies/product-market-codes/H4800X 615 0$aImmunology. 615 0$aRespiratory organs?Diseases. 615 0$aPathology. 615 14$aImmunology. 615 24$aPneumology/Respiratory System. 615 24$aPathology. 676 $a616.200471 702 $aRogers$b Thomas J$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aCriner$b Gerard J$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aCornwell$b William D$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910739487003321 996 $aSmoking and Lung Inflammation$93554610 997 $aUNINA