LEADER 06188nam 22008175 450 001 9910739473903321 005 20200705163456.0 010 $a3-319-22614-2 024 7 $a10.1007/978-3-319-22614-9 035 $a(CKB)3710000000486777 035 $a(EBL)4178500 035 $a(SSID)ssj0001585263 035 $a(PQKBManifestationID)16263057 035 $a(PQKBTitleCode)TC0001585263 035 $a(PQKBWorkID)14866318 035 $a(PQKB)10900047 035 $a(DE-He213)978-3-319-22614-9 035 $a(MiAaPQ)EBC4178500 035 $a(PPN)190532823 035 $a(EXLCZ)993710000000486777 100 $a20151008d2016 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aLIFE - AS A MATTER OF FAT $eLipids in a Membrane Biophysics Perspective /$fby Ole G. Mouritsen, Luis A. Bagatolli 205 $a2nd ed. 2016. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2016. 215 $a1 online resource (299 p.) 225 1 $aThe Frontiers Collection,$x1612-3018 300 $aDescription based upon print version of record. 311 $a3-319-22613-4 320 $aIncludes bibliographical references and index. 327 $aPrologue: Lipidology - the science of lipids -- I THE OVERLOOKED MOLECULES -- Life from molecules -- Head and tail -- Oil and water -- Lipids speak the language of curvature -- A matter of softness -- Soft shells shape up -- Biological membranes - models and fashion -- II LIPIDS MAKE SENSE -- Lipids in bilayers - a stress-full and busy life -- The more we are together -- Lipids in Flatland -- Social Lipids -- Lively lipids provide for function -- Proteins at lipid mattresses -- III LIPIDS IN ACTION -- Cholesterol on the scene -- Lipids in charge -- Being smart - a _shy matter of fat -- Liquor and drugs - as a matter of fat-. Lipid eaters -- Powerful and strange lipids at work -- Survival by lipids -- Epilogue: Fat for Future -- Bibliography -- Sources for Figures. ? Index. 330 $aThe present book gives a multi-disciplinary perspective on the physics of life and the particular role played by lipids (fats) and the lipid-bilayer component of cell membranes. The emphasis is on the physical properties of lipid membranes seen as soft and molecularly structured interfaces. By combining and synthesizing insights obtained from a variety of recent studies, an attempt is made to clarify what membrane structure is and how it can be quantitatively described. Furthermore, it is shown how biological function mediated by membranes is controlled by lipid membrane structure and organization on length scales ranging from the size of the individual molecule, across molecular assemblies of proteins and lipid domains in the range of nanometers, to the size of whole cells. Applications of lipids in nanotechnology and biomedicine are also described.   The first edition of the present book was published in 2005 when lipidomics was still very much an emerging science and lipids about to be recognized as being as important for life as proteins, sugars, and genes. This significantly expanded and revised edition takes into account the tremendous amount of knowledge gained over the past decade.  In addition, the book now includes more tutorial material on the biochemistry of lipids and the principles of lipid self-assembly.   The book is aimed at undergraduate students and young research workers within physics, chemistry, biochemistry, molecular biology, nutrition, as well as pharmaceutical and biomedical sciences.   From the reviews of the first edition:   "This is a highly interesting book and a pleasure to read. It represents a new and excellent pedagogical introduction to the field of lipids and the biophysics of biological membranes. I reckon that physicists and chemists as well as biologists will benefit from this approach to the field and Mouritsen shows a deep insight into the physical chemistry of lipids." (Göran Lindblom, Chemistry and Physics of Lipids 2005, vol. 135, page 105-106)   "The book takes the reader on an exciting journey through the lipid world, and Mouritsen attracts the attention with a lively style of writing ? . a comprehensive view of the ?lipid sea? can be easily achieved, gaining the right perspectives for envisaging future developments in the nascent field of lipidomics." (Carla Ferreri, ChemBioChem, Vol. 6 (8), 2005). 410 0$aThe Frontiers Collection,$x1612-3018 606 $aBiophysics 606 $aBiological physics 606 $aBioorganic chemistry 606 $aLipids 606 $aFood?Biotechnology 606 $aAmorphous substances 606 $aComplex fluids 606 $aBiological and Medical Physics, Biophysics$3https://scigraph.springernature.com/ontologies/product-market-codes/P27008 606 $aBioorganic Chemistry$3https://scigraph.springernature.com/ontologies/product-market-codes/C19010 606 $aLipidology$3https://scigraph.springernature.com/ontologies/product-market-codes/L14080 606 $aFood Science$3https://scigraph.springernature.com/ontologies/product-market-codes/C15001 606 $aSoft and Granular Matter, Complex Fluids and Microfluidics$3https://scigraph.springernature.com/ontologies/product-market-codes/P25021 615 0$aBiophysics. 615 0$aBiological physics. 615 0$aBioorganic chemistry. 615 0$aLipids. 615 0$aFood?Biotechnology. 615 0$aAmorphous substances. 615 0$aComplex fluids. 615 14$aBiological and Medical Physics, Biophysics. 615 24$aBioorganic Chemistry. 615 24$aLipidology. 615 24$aFood Science. 615 24$aSoft and Granular Matter, Complex Fluids and Microfluidics. 676 $a612.397 700 $aMouritsen$b Ole G$4aut$4http://id.loc.gov/vocabulary/relators/aut$049442 702 $aBagatolli$b Luis A$4aut$4http://id.loc.gov/vocabulary/relators/aut 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910739473903321 996 $aLIFE - AS A MATTER OF FAT$93553216 997 $aUNINA