LEADER 03657nam 22006495 450 001 9910739410003321 005 20200701001420.0 010 $a1-4614-8899-0 024 7 $a10.1007/978-1-4614-8899-6 035 $a(CKB)3710000000024857 035 $a(EBL)1466395 035 $a(OCoLC)861080783 035 $a(SSID)ssj0001049465 035 $a(PQKBManifestationID)11550228 035 $a(PQKBTitleCode)TC0001049465 035 $a(PQKBWorkID)11019821 035 $a(PQKB)11651048 035 $a(MiAaPQ)EBC1466395 035 $a(DE-He213)978-1-4614-8899-6 035 $a(PPN)176100008 035 $a(EXLCZ)993710000000024857 100 $a20131001d2014 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aHadron Therapy Physics and Simulations$b[electronic resource] /$fby Marcos d?Ávila Nunes 205 $a1st ed. 2014. 210 1$aNew York, NY :$cSpringer New York :$cImprint: Springer,$d2014. 215 $a1 online resource (108 p.) 225 1 $aSpringerBriefs in Physics,$x2191-5423 300 $aDescription based upon print version of record. 311 $a1-4614-8898-2 320 $aIncludes bibliographical references. 327 $aBrief History of Radiotherapy -- Time line of Hadron Therapy -- Mechanism of Hadron Therapy at molecular level -- Strengthening concepts about variations in therapy by radiation -- Which conditions can be treated by Hadron Therapy?- Hospitals and Research Centers for cancer treatment by Hadron -- Particle therapy facilities in operation (incl. patient statistics) -- Tumors: localization -- Using boro-therapy to treat tumors -- Which therapy must be used? Where? ?Conduct before and during treatment used at HIT -- After Modern Radiotherapy: estimating risk of second malignancies -- Particles and ions accelerators -- Simulations in Hadron Therapy. 330 $aThis brief provides an in-depth overview of the physics of hadron therapy, ranging from the history to the latest contributions to the subject. It covers the mechanisms of protons and carbon ions at the molecular level (DNA breaks and proteins 53BP1 and RPA), the physics and mathematics of accelerators (Cyclotron and Synchrotron), microdosimetry measurements (with new results so far achieved), and Monte Carlo simulations in hadron therapy using FLUKA (CERN) and MCHIT (FIAS) software. The text also includes information about proton therapy centers and carbon ion centers (PTCOG), as well as a comparison and discussion of both techniques in treatment planning and radiation monitoring. This brief is suitable for newcomers to medical physics as well as seasoned specialists in radiation oncology. 410 0$aSpringerBriefs in Physics,$x2191-5423 606 $aMedical physics 606 $aRadiation 606 $aBiophysics 606 $aBiological physics 606 $aMedical and Radiation Physics$3https://scigraph.springernature.com/ontologies/product-market-codes/P27060 606 $aBiological and Medical Physics, Biophysics$3https://scigraph.springernature.com/ontologies/product-market-codes/P27008 607 $aBrazil 615 0$aMedical physics. 615 0$aRadiation. 615 0$aBiophysics. 615 0$aBiological physics. 615 14$aMedical and Radiation Physics. 615 24$aBiological and Medical Physics, Biophysics. 676 $a571.4 700 $aNunes$b Marcos d?Ávila$4aut$4http://id.loc.gov/vocabulary/relators/aut$0791317 906 $aBOOK 912 $a9910739410003321 996 $aHadron Therapy Physics and Simulations$91768678 997 $aUNINA