LEADER 02586nas 2200493 n 450 001 990008943580403321 005 20240229084257.0 011 $a1251-8050 035 $a000894358 035 $aFED01000894358 035 $a(Aleph)000894358FED01 035 $a000894358 091 $2CNR$aP 00155025 100 $a20090724b19942001km-y0itaa50------ba 101 0 $afre 102 $aFR 110 $aauu-------- 200 1 $aComptes rendus de l'Académie des Sciences. Série 2: Sciences de la terre et des Planètes 207 1$a1994-2001 210 $aMontrouge$cGauthier-Villars;Elsevier;Elsevier 440 0$12001$aComptes Rendus. Académie des Sciences. Geoscience 443 0$1001000894356$12001$aComptes rendus de l'Académie des Sciences Série 2: Méchanique, physique, chimie, sciences de l'univers, sciences de la terre 452 0$12001$aComptes rendus de l'Académie des Sciences. Série 2: Sciences de la terre et des Planètes (On-line) 517 0 $aComptes rendus de l'Académie des sciences. Série II. Fascicule a, Sciences de la terre et des planètes 530 0 $aComptes rendus de l'Académie des Sciences. Série 2: Sciences de la terre et des Planètes 675 $a551 676 $a551 676 $a560 676 $a064 676 $a505 676 $a550.5 801 0$aIT$bACNP$c20090723 859 4 $uhttp://acnp.cib.unibo.it/cgi-ser/start/it/cnr/dc-p1.tcl?catno=917536&person=false&language=ITALIANO&libr=&libr_th=unina1$zBiblioteche che possiedono il periodico 901 $aSE 912 $a990008943580403321 958 $aBiblioteca del Gruppo Geomineralogico - Università degli studi di Napoli Federico II$b1994-2001.$fGM1 958 $aBiblioteca. Dipartimento di Patologia e Sanità Animale Sezione di Anatomia Patologica dell'Università Federico II$b1994-2001.$fDMVAP 959 $aGM1 959 $aDMVAP 996 $aComptes rendus de l'Académie des Sciences. Série 2: Sciences de la terre et des Planètes$9797171 997 $aUNINA AP1 8 $6866-01$aNA081 Biblioteca del Gruppo Geomineralogico - Università degli studi di Napoli Federico II$elargo San Marcellino, 10, 80138 Napoli (NA)$m0812538157$nit AP1 8 $6866-02$aNA091 Biblioteca. Dipartimento di Patologia e Sanità Animale Sezione di Anatomia Patologica dell'Università Federico II$ev. Delpino,1, Napoli (NA)$m(081) 2536467$nit AP2 40$aacnp.cib.unibo.it$nACNP Italian Union Catalogue of Serials$uhttp://acnp.cib.unibo.it/cgi-ser/start/it/cnr/df-p.tcl?catno=917536&language=ITALIANO&libr=&person=&B=1&libr_th=unina&proposto=NO LEADER 04455nam 2200613Ia 450 001 9910739403103321 005 20200520144314.0 010 $a1-62703-456-0 024 7 $a10.1007/978-1-62703-456-2 035 $a(CKB)2670000000388023 035 $a(EBL)1317564 035 $a(SSID)ssj0000925960 035 $a(PQKBManifestationID)11599201 035 $a(PQKBTitleCode)TC0000925960 035 $a(PQKBWorkID)10894658 035 $a(PQKB)11078377 035 $a(DE-He213)978-1-62703-456-2 035 $a(MiAaPQ)EBC1317564 035 $a(iGPub)SPNA0027091 035 $a(PPN)170489094 035 $a(EXLCZ)992670000000388023 100 $a20130508d2013 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aNew advances on disease biomarkers and molecular targets in biomedicine /$fNikki P. Lee, C. Y. Cheng, John M. Luk, editors 205 $a1st ed. 2013. 210 $aNew York $cHumana Press/Springer$dc2013 215 $a1 online resource (283 p.) 300 $aDescription based upon print version of record. 311 $a1-62703-901-5 311 $a1-62703-455-2 320 $aIncludes bibliographical references. 327 $aNon-receptor Protein Kinases c-Src, c-Yes and FAK are Biomarkers for Male Contraceptive Research -- Ankyrin Repeat and Suppressor of Cytokine Signaling Box (ASB) Family Members for Cancer Diagnosis, Prognosis, and Treatment -- MicroRNA as Cancer Biomarkers and Targets -- Oncofetal Molecules as Biomarkers and Drug Targets for Hepatic Cancer -- Ion channels as novel pancreatic cancer biomarkers and targets -- Circulating Biomarkers for Sophageal Squamous Cell Carcinoma -- Using Genomic Biomarkers to Predict Patient Prognosis and Treatment Response in Gastric Cancer -- CARF Regulates Cellular Senescence and Apoptosis by p53 Dependant and Independent Pathways -- Targeting Cancer Metabolisms -- Modulation of Autophagy as a Novel Cancer Therapeutic Strategy -- Functional proteomics screening for novel anti-viral drug targets -- Identification of Tumor Antigens as Targets for Novel Anti-tumor Therapies -- Mesoporous Silica Nanoparticles for Cancer Therapy -- Chemoresistance in Glioma. 330 $aRising occurrences of various diseases and epidemics have pressurized the already-burdened health system across the globe, and this imposes an unprecedented challenge on our current research in identifying disease-specific biomarkers and molecular targets, in particular for cancers, neurological disorders and unexplained infertility. Despite decades of efforts in deciphering the fundamental biology underlying various diseases at discrete levels using an array of advanced technologies, attempts to identify reliable and disease-indicating markers for detection and biomolecules or cellular structures for targeting are still in vain. This monograph describes and discusses the updated findings in this field with a specific aim to compile prior and recent literature and from there to acquire some insights to facilitate future research to expand our options of understanding, detecting and treating diseases. Among the many possible areas of biomedical research, this content comprises two themes: disease biomarkers and molecular targets. We also cover topics that are more advanced in development to emerging scientific discoveries. In particular, we have included in this monograph concepts on the renovated use of oncofetal molecules in cancer prediction and treatment, the evolving development in cancer biology at the cellular and molecular levels and the recent involvement on new classes of molecules in diseases. We hope that this book can renew established concepts in the field, and at the same time lead to important insights for research and development of drugs, diagnostics, and interventions for managing diseases of unmet medical needs. 606 $aBiochemical markers 606 $aGenomics 606 $aProteomics 615 0$aBiochemical markers. 615 0$aGenomics. 615 0$aProteomics. 676 $a610.157 701 $aLee$b Nikki P$01757404 701 $aCheng$b C. Y$01757405 701 $aLuk$b John M$01757406 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910739403103321 996 $aNew advances on disease biomarkers and molecular targets in biomedicine$94195241 997 $aUNINA