LEADER 04424nam 22006255 450 001 9910737300103321 005 20200702172849.0 010 $a3-030-13035-5 024 7 $a10.1007/978-3-030-13035-0 035 $a(CKB)4100000007817060 035 $a(MiAaPQ)EBC5741621 035 $a(DE-He213)978-3-030-13035-0 035 $a(PPN)235232084 035 $a(EXLCZ)994100000007817060 100 $a20190325d2019 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aYeasts in Biotechnology and Human Health $ePhysiological Genomic Approaches /$fedited by Isabel Sá-Correia 205 $a1st ed. 2019. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2019. 215 $a1 online resource (v, 242 pages) 225 1 $aProgress in Molecular and Subcellular Biology,$x0079-6484 ;$v58 311 $a3-030-13034-7 327 $aIndustrial Applications and Model Systems -- Physiological genomics of multistress resistance in the yeast cell model and factory: focus on MDR/MXR transporters -- Mechanisms of yeast adaptation to wine fermentations -- Development of robust yeast strains for lignocellulosic bio-refineries based on genome-wide studies -- Physiological genomics of the highly weak-acid-tolerant food spoilage yeasts of Zygosaccharomyces bailii sensu lato -- Yeast genome-scale metabolic models for simulating genotype-phenotype relations -- Human Health and Disease -- Emerging mechanisms of drug resistance in Candida albicans -- Genome-wide response to drugs and stress in the pathogenic yeast Candida glabrata -- Lipidomics approaches: applied to the study of pathogenesis in Candida species -- Yeast at the forefront of research on ageing and age-related diseases. 330 $aThis book discusses genome-based strategies to provide a holistic understanding of yeasts in Human Health and as model organisms in basic research or industrial production. Using numerous Saccharomyces cerevisiae strains and various non-conventional yeast species isolated from diverse origins, it describes essential biological processes, the biotechnological exploitation of yeast and pathogenesis control. It also demonstrates how functional and comparative genomics and the development of genome engineering tools are used in modern yeast research. The use of yeasts as experimental eukaryotic models increasingly gained prominence when several Nobel Prizes in Physiology/Medicine and Chemistry were awarded for innovative research, using yeast strains to elucidate molecular mechanisms in a wide range of human physiological processes and diseases, such as autophagy, cell cycle regulation and telomerase activity. This book offers useful insights for scientists in yeast research, clinical scientists working with yeast infectious models and for industrial researchers using applied microbiology. 410 0$aProgress in Molecular and Subcellular Biology,$x0079-6484 ;$v58 606 $aMicrobiology 606 $aMicrobial genetics 606 $aMicrobial genomics 606 $aMedical microbiology 606 $aBiomedical engineering 606 $aEukaryotic Microbiology$3https://scigraph.springernature.com/ontologies/product-market-codes/L23020 606 $aMicrobial Genetics and Genomics$3https://scigraph.springernature.com/ontologies/product-market-codes/L32010 606 $aApplied Microbiology$3https://scigraph.springernature.com/ontologies/product-market-codes/C12010 606 $aMedical Microbiology$3https://scigraph.springernature.com/ontologies/product-market-codes/B16003 606 $aBiomedical Engineering/Biotechnology$3https://scigraph.springernature.com/ontologies/product-market-codes/B24000 615 0$aMicrobiology. 615 0$aMicrobial genetics. 615 0$aMicrobial genomics. 615 0$aMedical microbiology. 615 0$aBiomedical engineering. 615 14$aEukaryotic Microbiology. 615 24$aMicrobial Genetics and Genomics. 615 24$aApplied Microbiology. 615 24$aMedical Microbiology. 615 24$aBiomedical Engineering/Biotechnology. 676 $a660.62 702 $aSá-Correia$b Isabel$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910737300103321 996 $aYeasts in Biotechnology and Human Health$93459249 997 $aUNINA