LEADER 03439nam 22006735 450 001 9910736984503321 005 20251008163434.0 010 $a9789811974199 010 $a9811974195 024 7 $a10.1007/978-981-19-7419-9 035 $a(MiAaPQ)EBC30674564 035 $a(CKB)27922755700041 035 $a(Au-PeEL)EBL30674564 035 $a(DE-He213)978-981-19-7419-9 035 $a(PPN)272269352 035 $a(OCoLC)1392340343 035 $a(EXLCZ)9927922755700041 100 $a20230803d2023 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aEpigenetic Mechanisms of Cell Programming and Reprogramming /$fedited by Gang Pei 205 $a1st ed. 2023. 210 1$aSingapore :$cSpringer Nature Singapore :$cImprint: Springer,$d2023. 215 $a1 online resource (68 pages) 225 1 $aReports of China?s Basic Research,$x2731-8915 311 0 $a9789811974182 327 $a1. Project Overview -- 2. Domestic and Foreign Research -- 3. Major Research Achievements -- 4.Outlook. 330 $aThis book presents a major research program on epigenetic mechanisms of cell programming and reprogramming. The program was launched by the National Natural Science Foundation of China during the 11th Five-Year Plan period, which was started in October 2008 and concluded at the end of 2016. It first summarizes the epigenetic research plans and the current situation of epigenetic research in China and the international frontier. With the application of interdisciplinary research methods, the book discusses the development trends of epigenetic research, such as mechanisms of establishment and maintenance of epigenetic information and epigenetic regulation on reproduction and development. It also presents a variety of research achievements. For example, the discovery of new epigenetic regulators and chromatin remodulaters and their biological functions and mechanisms are highlighted. Several regulation mechanisms of cell differentiation and trans-differentiation are discussed, especially the discovery of the key factors to promote the trans-differentiation of somatic cells to hepatocytes. In addition, this book puts forward some key academic fields with increasing importance, such as biochemistry, cell biology, and clinical medicine. Given its scope, the book is of interest to researchers who work in cell biology, biochemistry, structural biology, bioinformatics, clinical medicine, and other related fields. . 410 0$aReports of China?s Basic Research,$x2731-8915 606 $aBiochemistry 606 $aCytology 606 $aMedical genetics 606 $aBiomaterials 606 $aNucleic acids 606 $aBiochemistry 606 $aCell Biology 606 $aMedical Genetics 606 $aNucleic Acid 615 0$aBiochemistry. 615 0$aCytology. 615 0$aMedical genetics. 615 0$aBiomaterials. 615 0$aNucleic acids. 615 14$aBiochemistry. 615 24$aCell Biology. 615 24$aMedical Genetics. 615 24$aNucleic Acid. 676 $a572 701 $aPei$b Gang$01381736 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910736984503321 996 $aEpigenetic Mechanisms of Cell Programming and Reprogramming$93424586 997 $aUNINA