LEADER 00860nam0-22003131i-450- 001 990007218470403321 005 20021010 035 $a000721847 035 $aFED01000721847 035 $a(Aleph)000721847FED01 035 $a000721847 100 $a20021010d--------km-y0itay50------ba 101 0 $aita 200 1 $a<>competenza esperta$eSapere professionale e contesti di lavoro$fAnna Maria Ajello, Marida Cevoli, Saul Meghnagi 210 $aRoma$cEdiesse$d1992 215 $a143 p., 21 cm 225 1 $aIRES 676 $a344 700 1$aAjello,$bAnna Maria$0148986 702 1$aCevoli,$bMarida 702 1$aMeghnagi,$bSaul 801 0$aIT$bUNINA$gRICA$2UNIMARC 901 $aBK 912 $a990007218470403321 952 $aB-XI-56$b2798$fDDRC 959 $aDDRC 996 $aCompetenza esperta$9274801 997 $aUNINA DB $aGEN01 LEADER 04330nam 22006615 450 001 9910734874703321 005 20251008140716.0 010 $a3-031-26945-4 024 7 $a10.1007/978-3-031-26945-5 035 $a(MiAaPQ)EBC30651885 035 $a(Au-PeEL)EBL30651885 035 $a(DE-He213)978-3-031-26945-5 035 $a(PPN)272255556 035 $a(CKB)27627167700041 035 $a(EXLCZ)9927627167700041 100 $a20230716d2023 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aPurinergic Signaling in Neurodevelopment, Neuroinflammation and Neurodegeneration /$fedited by Henning Ulrich, Peter Illes, Talita Glaser 205 $a1st ed. 2023. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2023. 215 $a1 online resource (381 pages) 311 08$aPrint version: Ulrich, Henning Purinergic Signaling in Neurodevelopment, Neuroinflammation and Neurodegeneration Cham : Springer International Publishing AG,c2023 9783031269448 320 $aIncludes bibliographical references and index. 327 $aThe Purinergic Signaling: Overview -- Adenosine A2A Receptor-containing Heteromers and Neuroprotection -- Purinergic Signaling in Brain Physiology -- Neurotrophic Actions of Adenosine and Guanosine: Implications for Neural Development and Regeneration? -- Purinergic Signaling in Neurogenesis and Neural Fate Determination: Current Knowledge and Future Challenges -- Purinergic Signaling in Autism Spectrum Disorder -- Purinergic Signaling in Depression -- Roles of Purinergic Receptors in Alzheimer's Disease -- Purinergic Signaling in Basal Ganglia Diseases: Parkinson's Disease -- A Step in the ALS Direction: Lessons from the Purinome -- Purinergic P2 Receptors in Epilepsy -- Purinergic Signaling in Neuroinflammation -- Purinergic Signaling in Brain Tumors -- Development of Purinergic Receptor Agonists and Antagonists -- Acupuncture for Counteracting P2X4 and P2X7 Receptor Involvement in Neuroinflammation. 330 $aThis volume explores the quickly evolving field of Purinergic signaling, and examines how receptors for ATP and other nucleotides, and receptors for adenosine, act in neuronal transmission, control of synaptic activity, proliferation, differentiation and cell death regulation in the CNS. This book focuses on the participation of purinergic receptors and ectonucleotidases, degrading ATP into adenosine, in embryonic and adult neurogenesis in vitro and in vivo as well as in synaptic transmission and pathophysiology. Further, the chapters discuss varying brain diseases, including Parkinson?s, and Alzheimer?s disease, autism, mood disorders and epilepsy, as well as brain tumors, in the context of purinergic signaling and its clinical aspects. The development of purinergic receptor agonists is also an important issue of this book. This book provides a critical review of the current state of science and will be useful for both scientists and students who are or would like to get involved in this area. Furthermore, this book addresses neuroscientists, physician and professionals from the industry, who would like to update themselves in this exciting and rapidly growing field of neuroscience. 606 $aNeurosciences 606 $aNeurochemistry 606 $aMedicine$xResearch 606 $aBiology$xResearch 606 $aRegenerative medicine 606 $aNeuroscience 606 $aNeurochemistry 606 $aBiomedical Research 606 $aRegenerative Medicine and Tissue Engineering 615 0$aNeurosciences. 615 0$aNeurochemistry. 615 0$aMedicine$xResearch. 615 0$aBiology$xResearch. 615 0$aRegenerative medicine. 615 14$aNeuroscience. 615 24$aNeurochemistry. 615 24$aBiomedical Research. 615 24$aRegenerative Medicine and Tissue Engineering. 676 $a616.80442 702 $aUlrich$b Henning 702 $aIlles$b Peter 702 $aGlaser$b Talita 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910734874703321 996 $aPurinergic signaling in neurodevelopment, neuroinflammation and neurodegeneration$93552556 997 $aUNINA