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101 0 $aeng
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181   $ctxt$2rdacontent
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200 10$aLassa Fever: Epidemiology, Immunology, Diagnostics, and Therapeutics /$fedited by Robert Garry
205   $a1st ed. 2023.
210  1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2023.
215   $a1 online resource (199 pages)
225 1 $aCurrent Topics in Microbiology and Immunology,$x2196-9965 ;$v440
311 08$aPrint version: Garry, Robert Lassa Fever: Epidemiology, Immunology, Diagnostics, and Therapeutics Cham : Springer International Publishing AG,c2023 9783031358067 
320   $aIncludes bibliographical references.
327   $a50 years of Lassa fever research -- Lassa Virus Genetics -- Ecology of Lassa virus -- Epidemiology of Lassa Fever -- Lassa virus countermeasures -- Lassa virus structural biology and replication -- Lassa Fever Natural History and Clinical Management.
330   $aThis volume provides a comprehensive and up-to-date overview of the various aspects of Lassa virus (LASV), the causative agent of Lassa fever, a frequently fatal zoonotic disease endemic to West Africa. Compiled by world-leading experts in the field, this book provides an introduction to the 50-year history of Lassa fever research, the genetic diversity of LASV, and its geographic distribution. Subsequent chapters focus on the ecology and epidemiology of LASV, discussing in-depth the interactions of the virus with its hosts - multimammate mice and other rodents - and the interactions between these animal reservoirs and humans. The book also details the many advances in understanding the structural biology and replication of LASV, including new insights into the structure and function of its proteins. These advances in the basic understanding of LASV biology have enabled the development of LASV countermeasures, including sensitive and specific diagnostic assays. Promising drug candidates, including monoclonal antibodies, and vaccines are also discussed. A final and essential chapter addresses current and future clinical practice for clinical management of Lassa fever. This volume is intended for researchers and clinicians in the fields of virology, epidemiology, and microbiology.
410  0$aCurrent Topics in Microbiology and Immunology,$x2196-9965 ;$v440
606   $aVirology
606   $aMedical microbiology
606   $aInternal medicine
606   $aTropical medicine
606   $aVirology
606   $aMedical Microbiology
606   $aInternal Medicine
606   $aTropical Medicine
615  0$aVirology.
615  0$aMedical microbiology.
615  0$aInternal medicine.
615  0$aTropical medicine.
615 14$aVirology.
615 24$aMedical Microbiology.
615 24$aInternal Medicine.
615 24$aTropical Medicine.
676   $a616.91
702   $aGarry$b Robert
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801  1$bMiAaPQ
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906   $aBOOK
912   $a9910734856603321
996   $aLassa Fever$93403949
997   $aUNINA