LEADER 04239nam 22007455 450 001 9910733728803321 005 20251008140550.0 010 $a3-031-23965-2 024 7 $a10.1007/978-3-031-23965-6 035 $a(CKB)5580000000531635 035 $a(DE-He213)978-3-031-23965-6 035 $a(MiAaPQ)EBC7240944 035 $a(Au-PeEL)EBL7240944 035 $a(PPN)269657940 035 $a(MiAaPQ)EBC7239119 035 $a(EXLCZ)995580000000531635 100 $a20230419d2023 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aCardiac Mechanobiology in Physiology and Disease /$fedited by Markus Hecker, Dirk J. Duncker 205 $a1st ed. 2023. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2023. 215 $a1 online resource (VIII, 353 p. 1 illus.) 225 1 $aCardiac and Vascular Biology,$x2509-7849 ;$v9 311 08$a3-031-23964-4 320 $aIncludes bibliographical references. 327 $aForeword -- Cardiac mechanoperception and mechanotransduction - Mechanisms of stretch sensing in cardiomyocytes and implications for cardiomyopathy -- Mechanotransduction in heart development -- Mechanobiology of cardiac growth in health and disease -- The role of mechanosensitive signaling cascades in repair and fibrotic remodeling of the infarcted heart -- Mechanobiology of cardiac fibroblasts in cardiac remodelling -- Mechanobiology of cardiac remodelling in cardiomyopathy -- Biophysical Stretch Induced Differentiation and Maturation of Induced Pluripotent Stem Cell-derived Cardiomyocytes -- Mechanical Considerations of Myocardial Tissue and Cardiac Regeneration -- Mechanobiology of Exercise-Induced Cardiac Remodeling in Health and Disease -- Cardiac microvascular endothelial cells and pressure overload-induced cardiac fibrosis -- Cellular and Subcellular Mechanisms of Ventricular Mechano-Arrhythmogenesis -- Computational biomechanics of ventricular dyssynchrony and resynchronization therapy -- Therapeutic innovations for heart failure. 330 $aThis book presents the latest findings in the field of cardiac mechanobiology in health and disease. Cardiac mechanobiology provides knowledge of all aspects of mechanobiology of the heart. Cardiomyogenesis is discussed as well as the mechanobiology of cardiac remodeling and regeneration. The molecular mechanisms of mechanoperception and mechanotransduction in cardiomyocytes are explained, as well as stretch induced differentiation of cardiomyocytes derived from induced pluripotent stem cells. This volume of the series Cardiac and Vascular Biology complements the volume Vascular Mechanobiology in Physiology and Disease (volume 8) published in this series. The book is aimed at clinicians as well as researchers in cardiovascular biology, bioengineering and biophysics, and also represents an educational resource for young researchers and students in these fields. 410 0$aCardiac and Vascular Biology,$x2509-7849 ;$v9 606 $aCardiovascular system 606 $aPhysiology 606 $aBiophysics 606 $aCell interaction 606 $aMedicine$xResearch 606 $aBiology$xResearch 606 $aRegenerative medicine 606 $aCardiovascular Physiology 606 $aMechanobiological Cell Signaling 606 $aBiomedical Research 606 $aRegenerative Medicine and Tissue Engineering 615 0$aCardiovascular system. 615 0$aPhysiology. 615 0$aBiophysics. 615 0$aCell interaction. 615 0$aMedicine$xResearch. 615 0$aBiology$xResearch. 615 0$aRegenerative medicine. 615 14$aCardiovascular Physiology. 615 24$aMechanobiological Cell Signaling. 615 24$aBiomedical Research. 615 24$aRegenerative Medicine and Tissue Engineering. 676 $a658 676 $a612.17 702 $aHecker$b Markus 702 $aDuncker$b Dirk J. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910733728803321 996 $aCardiac Mechanobiology in Physiology and Disease$93397697 997 $aUNINA