LEADER 03246nam 22005055 450 001 9910733726503321 005 20200629152746.0 010 $a3-319-91220-8 024 7 $a10.1007/978-3-319-91220-2 035 $a(CKB)4100000005679209 035 $a(DE-He213)978-3-319-91220-2 035 $a(MiAaPQ)EBC5493428 035 $z(PPN)258872284 035 $a(PPN)229918263 035 $a(EXLCZ)994100000005679209 100 $a20180813d2018 u| 0 101 0 $aeng 135 $aurnn#008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aPharmaceutical Powder and Particles /$fby Anthony J. Hickey, Stefano Giovagnoli 205 $a1st ed. 2018. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2018. 215 $a1 online resource (IX, 104 p. 35 illus., 13 illus. in color.) 225 1 $aAAPS Introductions in the Pharmaceutical Sciences,$x2522-834X 311 08$aPrint version Hickey, Anthony J., 1955- Pharmaceutical powder and particles 3-319-91219-4 327 $aIntroduction -- Importance of Finely Divided Solids in Pharmaceutical Dosage Forms -- Solid State Chemistry -- Crystallization -- Physical Properties -- Particle Size and Size Distribution -- Particle Size Characterization -- Fundamental of Particle Interactions -- Powder and Particle Dependent Traditional Manufacturing Processes (unit operations) -- Powder and Particle Dependent Biopharmaceutical Processes -- Recent and Evolving Manufacturing Processes -- Principles of Quality by Design -- General Discussion. 330 $aThis first monograph in the new AAPS book series concisely reviews important aspects of powder and particle systems and the critical quality attributes that should be used as a guide to future developments intended to maximize the control of product quality and performance. Drs. Hickey and Giovagnoli have written an essential primer for any scientists involved in powder or particle research and manufacturing. Pharmaceutical Powder and Particles is appropriate for those just entering the field or as a rapid reference for the experienced pharmaceutical scientist.The authors have both academic and industrial experience and the coverage includes solid state chemistry; crystallization; physical processes; particle size and distribution; particle interaction; manufacturing processes; quality by design;and a general discussion of the industry. . 410 0$aAAPS Introductions in the Pharmaceutical Sciences,$x2522-834X 606 $aPharmacology 606 $aPharmacy 606 $aPharmacology/Toxicology$3https://scigraph.springernature.com/ontologies/product-market-codes/B21007 606 $aPharmacy$3https://scigraph.springernature.com/ontologies/product-market-codes/F00008 615 0$aPharmacology. 615 0$aPharmacy. 615 14$aPharmacology/Toxicology. 615 24$aPharmacy. 676 $a615 700 $aHickey$b Anthony J$4aut$4http://id.loc.gov/vocabulary/relators/aut$0554307 702 $aGiovagnoli$b Stefano$4aut$4http://id.loc.gov/vocabulary/relators/aut 906 $aBOOK 912 $a9910733726503321 996 $aPharmaceutical Powder and Particles$93397681 997 $aUNINA