LEADER 03222nam 22006015 450 001 9910733724203321 005 20230613192800.0 010 $a3-319-45618-0 024 7 $a10.1007/978-3-319-45618-8 035 $a(CKB)3710000001045316 035 $a(DE-He213)978-3-319-45618-8 035 $a(MiAaPQ)EBC4800173 035 $a(PPN)19887099X 035 $a(EXLCZ)993710000001045316 100 $a20170203d2017 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aProgress in the Chemistry of Organic Natural Products 104 /$fedited by A. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Jun'ichi Kobayashi 205 $a1st ed. 2017. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2017. 215 $a1 online resource (V, 246 p. 240 illus., 69 illus. in color.) 225 1 $aProgress in the Chemistry of Organic Natural Products,$x2192-4309 ;$v104 311 $a3-319-45616-4 320 $aIncludes bibliographical references at the end of each chapters. 330 $aThe first contribution describes apolar and polar molecular fossils and, in particular biomarkers, along the lines usually followed in organic chemistry textbooks, and points to their bioprecursors when available. Thus, the apolar compounds are divided in linear and branched alkanes followed by alicyclic compounds and aromatic and heterocyclic molecules, and, in particular, the geoporphyrins. The polar molecular fossils contain as functional groups or constituent units ethers, alcohols, phenols, carbonyl groups, flavonoids, quinones, and acids, or are polymers like kerogen, amber, melanin, proteins, or nucleic acids. The final sections discuss the methodology used and the fundamental processes encountered by the biomolecules described, including diagenesis, catagenesis, and metagenesis. The second contribution covers the distribution of phthalides in nature and the findings in the structural diversity, chemical reactivity, biotransformations, syntheses, and bioactivity of natural and semisynthetic phthalides. 410 0$aProgress in the Chemistry of Organic Natural Products,$x2192-4309 ;$v104 606 $aChemistry, Organic 606 $aPharmaceutical chemistry 606 $aMedicinal chemistry 606 $aOrganic Chemistry 606 $aPharmaceutics 606 $aMedicinal Chemistry 615 0$aChemistry, Organic. 615 0$aPharmaceutical chemistry. 615 0$aMedicinal chemistry. 615 14$aOrganic Chemistry. 615 24$aPharmaceutics. 615 24$aMedicinal Chemistry. 676 $a547 702 $aKinghorn$b A. Douglas$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aFalk$b Heinz$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aGibbons$b Simon$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aKobayashi$b Jun'ichi$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910733724203321 996 $aProgress in the Chemistry of Organic Natural Products 104$93393769 997 $aUNINA