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010   $a981-19-9925-2
024 7 $a10.1007/978-981-19-9925-3
035   $a(CKB)26748172900041
035   $a(MiAaPQ)EBC7248778
035   $a(Au-PeEL)EBL7248778
035   $a(DE-He213)978-981-19-9925-3
035   $a(PPN)270618643
035   $a(EXLCZ)9926748172900041
100   $a20230510d2023      u|         0
101 0 $aeng
135   $aurcnu||||||||
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aGenetics and Epigenetics of Breast Cancer /$fby Madhumita Roy, Jaydip Biswas, Amitava Datta
205   $a1st ed. 2023.
210  1$aSingapore :$cSpringer Nature Singapore :$cImprint: Springer,$d2023.
215   $a1 online resource $cillustrations
311   $a9789811999246 
320   $aIncludes bibliographical references.
327   $aChapter 1. Breast cancer -- Chapter 1.1. Epidemiology -- Chapter 1.2. Etiology -- Chapter 1.3. Types of breast cancer -- Chapter 1.4. Signs and symptoms -- Chapter 1.5. Stages -- Chapter 1.6. Diagnosis -- Chapter 1.7. Treatment -- Chapter 2. Genetic landscape of breast carcinogenesis -- Chapter 2.1. Hormone receptor positive breast cancer -- Chapter 2.1. Her2 positive breast cancer -- Chapter 2.2. Triple negative breast cancer  -- Chapter 3. Epigenetic involvement in breast carcinogenesis -- Chapter 3.1. Histone modification -- Chapter 3.2. DNA methylation -- Chapter 3.3. miRNA -- Chapter 4. Breast cancer control -- Chapter 4.1. Conventional drugs targeting Genetic and Epigenetics in Breast cancer -- Chapter 4.2. Pitfalls of conventional therapy -- Chapter 4.3. Natural remediation -- Chapter 5. Conclusion.
330   $aThis book discusses the contribution of genetics and epigenetics alterations in the initiation, development, and recurrence of breast cancer. It also reviews the potential of translating the epigenetic alterations into diagnosis, prognosis, and breast cancer therapy. The initial chapters explore the epigenetics, etiology, and conventional treatment strategies for breast cancer. The subsequent chapters discuss the genetic landscape and cover three main epigenetic modulation mechanisms; histone modification, DNA methylation, and miRNA silencing. Further, the book explores the potential of epigenetic drugs in treating breast cancer. Lastly, it covers the phytochemicals targeting epigenetic modulators in breast cancer treatment. This book is an essential source for researchers and practitioners interested in exploring the potential of epigenetics modulators in breast cancer treatment.
606   $aCancer
606   $aCancer?Genetic aspects
606   $aCancer?Treatment
606   $aCancer Biology
606   $aCancer Genetics and Genomics
606   $aCancer Therapy
615  0$aCancer.
615  0$aCancer?Genetic aspects.
615  0$aCancer?Treatment.
615 14$aCancer Biology.
615 24$aCancer Genetics and Genomics.
615 24$aCancer Therapy.
676   $a616.99449042
700   $aRoy$b Madhumita$0872807
702   $aBiswas$b Jaydip
702   $aDatta$b A$g(Amitava),
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910726293803321
996   $aGenetics and epigenetics of breast cancer$93382897
997   $aUNINA