LEADER 02447nam 2200409 450 001 9910720571703321 005 20230627153648.0 024 7 $a10.1201/b13591 035 $a(CKB)5710000000124018 035 $a(NjHacI)995710000000124018 035 $a(EXLCZ)995710000000124018 100 $a20230627d2010 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 04$aThe cost manual of laboratory animal care and use $erefinement, reduction, and research /$fedited by Bryan Howard, Timo Nevalainen, Gemma Perretta 210 1$aBoca Raton, FL :$cTaylor and Francis, an imprint of CRC Press,$d2010. 215 $a1 online resource (439 pages) $cillustrations 327 $aChapter 1 Introduction -- chapter 2 Design and Oversight of Laboratory Animal Facilities -- chapter 3 Housing and Care of Laboratory Animals -- chapter 4 Animal Needs and Environmental Refinement -- chapter 5 Ethical Evaluation of ScientificProcedures: Recommendations for Ethics Committees -- chapter 6 Reduction by Careful Design and Statistical Analysis -- chapter 7 Animal Models: Selecting and Preparing Animals for a Study -- chapter 8 Creation of Genetically Modified Animals -- chapter 9 Management of Genetically Modified Rodents -- chapter 10 Impact of Handling, Radiotelemetry, and Food Restriction -- chapter 11 Basic Procedures: Dosing, Sampling and Immunisation -- chapter 12 Imaging Techniques -- chapter 13 Anaesthesia and Analgesia -- chapter 14 Use of Humane Endpointsto Minimise Suffering -- chapter 15 Euthanasia -- chapter 16 Education, Training, and Competence -- chapter 17 Animal Experimentation and Open Communication. 330 $aCOST (European Cooperation in the field of Scientific and Technical Research) is an intergovernmental initiative in science and research intended to promote the coordination of nationally funded research in Europe. 517 $aCOST Manual of Laboratory Animal Care and Use 606 $aAnimal welfare 606 $aLaboratory animals 615 0$aAnimal welfare. 615 0$aLaboratory animals. 676 $a179.3 702 $aHoward$b Bryan 702 $aNevalainen$b Timo 702 $aPerretta$b Gemma 801 0$bNjHacI 801 1$bNjHacl 906 $aBOOK 912 $a9910720571703321 996 $aThe cost manual of laboratory animal care and use$92116906 997 $aUNINA